Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Martín G, Martín"'
Autor:
Geoanna M. Bautista, Genia Dubrovsky, Nicolle K. Sweeney, R.S. Solórzano-Vargas, Daniel J. Tancredi, Michael Lewis, Mattias Stelzner, Martín G. Martín, James C.Y. Dunn
Publikováno v:
Frontiers in Gastroenterology, Vol 3 (2024)
IntroductionSevere forms of short bowel syndrome (SBS) resulting in chronic intestinal failure (IF) have limited therapeutic options, all of which are associated with significant morbidities. Spring-mediated distraction enterogenesis (SMDE) uses an i
Externí odkaz:
https://doaj.org/article/889499c589ac48a9b27f5a96d65aacaf
Autor:
Andrew Scott, Barbara Olack, Joshua D. Rouch, Hassan A. Khalil, Brent A. Kokubun, Nan Ye Lei, Jiafang Wang, Sergio Solorzano, Michael Lewis, James C.Y. Dunn, Matthias G. Stelzner, Joyce C. Niland, Martín G. Martín
Publikováno v:
Cell Transplantation, Vol 29 (2020)
Human small intestinal crypts are the source of intestinal stem cells (ISCs) that are capable of undergoing self-renewal and differentiation to an epithelial layer. The development of methods to expand the ISCs has provided opportunities to model hum
Externí odkaz:
https://doaj.org/article/f175a77a2732420e9c1157f0f7206595
Autor:
Qianqian Wang, Ke Wang, R Sergio Solorzano-Vargas, Po-Yu Lin, Christopher M Walthers, Anne-Laure Thomas, Martín G Martín, James C Y Dunn
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0195315 (2018)
Although critical for studies of gut motility and intestinal regeneration, the in vitro culture of intestinal muscularis with peristaltic function remains a significant challenge. Periodic contractions of intestinal muscularis result from the coordin
Externí odkaz:
https://doaj.org/article/3035547c8dcc4a8d9a7fe06dbcc03d3d
Development of Functional Microfold (M) Cells from Intestinal Stem Cells in Primary Human Enteroids.
Autor:
Joshua D Rouch, Andrew Scott, Nan Ye Lei, R Sergio Solorzano-Vargas, Jiafang Wang, Elaine M Hanson, Masae Kobayashi, Michael Lewis, Matthias G Stelzner, James C Y Dunn, Lars Eckmann, Martín G Martín
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0148216 (2016)
BACKGROUND & AIMS:Intestinal microfold (M) cells are specialized epithelial cells that act as gatekeepers of luminal antigens in the intestinal tract. They play a critical role in the intestinal mucosal immune response through transport of viruses, b
Externí odkaz:
https://doaj.org/article/07d8f5cad876469394a0a3f303e6097e
Autor:
Qianqian Wang, Jiafang Wang, Elmira Tokhtaeva, Zhen Li, Martín G. Martín, Xuefeng B. Ling, James C. Y. Dunn
Publikováno v:
Advanced Materials. :2207255
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cfea94063a95f47535b7bd7dc6f188a
https://doi.org/10.1002/adma.202207255
https://doi.org/10.1002/adma.202207255
Autor:
Hassan A Khalil, Nan Ye Lei, Wenxian Nie, Michael S Lewis, Matthias G Stelzner, Martín G Martín, James C Y Dunn, James Yoo
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0127258 (2015)
The myofibroblast is an important stromal cell of the gastrointestinal tract. Current in vitro and in vivo models either do not accurately recreate stromal-epithelial interactions or are not specific to myofibroblasts. We sought to create an animal m
Externí odkaz:
https://doaj.org/article/6412448df3d54bc5801e2d39071dd27f
Autor:
Nan Ye Lei, Ziyad Jabaji, Jiafang Wang, Vaidehi S Joshi, Garrett J Brinkley, Hassan Khalil, Fengchao Wang, Artur Jaroszewicz, Matteo Pellegrini, Linheng Li, Michael Lewis, Matthias Stelzner, James C Y Dunn, Martín G Martín
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e84651 (2014)
Intestinal epithelial stem cells (ISCs) are the focus of recent intense study. Current in vitro models rely on supplementation with the Wnt agonist R-spondin1 to support robust growth, ISC self-renewal, and differentiation. Intestinal subepithelial m
Externí odkaz:
https://doaj.org/article/2eafb19bbe58498395971442cc53b9f9
Autor:
Ziyad Jabaji, Garrett J Brinkley, Hassan A Khalil, Connie M Sears, Nan Ye Lei, Michael Lewis, Matthias Stelzner, Martín G Martín, James C Y Dunn
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107814 (2014)
BACKGROUND:We previously reported in vitro maintenance and proliferation of human small intestinal epithelium using Matrigel, a proprietary basement membrane product. There are concerns over the applicability of Matrigel-based methods for future huma
Externí odkaz:
https://doaj.org/article/779ce25d251b4da1a717cce68e2bc446
Autor:
Lindsay A Pickett, Michael Yourshaw, Valeria Albornoz, Zijun Chen, R Sergio Solorzano-Vargas, Stanley F Nelson, Martín G Martín, Iris Lindberg
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e55065 (2013)
BACKGROUND:Common single nucleotide polymorphisms (SNPs) in proprotein convertase subtilisin/kexin type 1 with modest effects on PC1/3 in vitro have been associated with obesity in five genome-wide association studies and with diabetes in one genome-
Externí odkaz:
https://doaj.org/article/ede830b32c694d45b918c1de297f7e28
Autor:
Nicholas Lahar, Nan Ye Lei, Jiafang Wang, Ziyad Jabaji, Stephaine C Tung, Vaidehi Joshi, Michael Lewis, Matthias Stelzner, Martín G Martín, James C Y Dunn
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e26898 (2011)
The intestinal crypt-niche interaction is thought to be essential to the function, maintenance, and proliferation of progenitor stem cells found at the bases of intestinal crypts. These stem cells are constantly renewing the intestinal epithelium by
Externí odkaz:
https://doaj.org/article/310e33631ab744889ea7d85fa4dd02e3