Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Martín E. García Solá"'
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Akademický článek
A Non-Coding RNA Network Involved in KSHV Tumorigenesis
Autor: Julián Naipauer, Martín E. García Solá, Daria Salyakina, Santas Rosario, Sion Williams, Omar Coso, Martín C. Abba, Enrique A. Mesri, Ezequiel Lacunza
Publikováno v: Frontiers in Oncology, Vol 11 (2021)
Regulatory pathways involving non-coding RNAs (ncRNAs), such as microRNAs (miRNAs) and long non-coding RNAs (lncRNA), have gained great relevance due to their role in the control of gene expression modulation. Using RNA sequencing of KSHV Bac36 trans
Externí odkaz: https://doaj.org/article/dc4bc52eeeac495798c79437d7886da7
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2
An Integrative Single-cell Transcriptomic Atlas of the Post-natal Mouse Mammary Gland Allows Discovery of New Developmental Trajectories in the Luminal Compartment
Autor: Inés Beckerman, Edith C. Kordon, Micaela Nadia Stedile, Martín E García Solá
Publikováno v: Journal of Mammary Gland Biology and Neoplasia. 26:29-42
The mammary gland is a highly dynamic organ which undergoes periods of expansion, differentiation and cell death in each reproductive cycle. Partly because of the dynamic nature of the gland, mammary epithelial cells (MECs) are extraordinarily hetero
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42bb2621e836a255305aa4e00c15bab2
https://doi.org/10.1007/s10911-021-09488-1
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3
R‐spondin‐mediatedWNTsignaling potentiation in mammary and breast cancer development
Autor: Carla M. Felcher, Martín E García Solá, Johanna M. Tocci, Edith C. Kordon
Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
The mammary gland is a secretory organ, which develops as a network of growing epithelial ducts composed of luminal and basal cells that invade the surrounding adipose tissue through a series of developmental cycles. Mammary stem cells (MaSCs) mainta
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e11cf098c70bf0c6a3f57eaa5c2ab44a
https://doi.org/10.1002/iub.2278
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4
Dengue virus targets RBM10 deregulating host cell splicing and innate immune response
Autor: Maria Florencia Torti, Leopoldo German Gebhard, Rita Vaz-Drago, Martín E García Solá, Pablo Mammi, Berta Pozzi, Andrea V. Gamarnik, Cybele C. García, Nicolás Gaioli, Laureano Bragado, Nestor Gabriel Iglesias, Anabella Srebrow
Publikováno v: Nucleic Acids Research
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
© The Author(s) 2020. Published by Oxford University Press on behalf of Nucleic Acids Research. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/license
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b17a2664c5fa2fbd41edd0cb07d86dc0
https://pubmed.ncbi.nlm.nih.gov/32432721
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5
Regulation of the Expression of Heme Oxygenase-1: Signal Transduction, Gene Promoter Activation, and Beyond
Autor: Daiana Sapochnik, Martín E García Solá, Omar A. Coso, María Victoria Medina
Publikováno v: Antioxid Redox Signal
Significance: Heme oxygenase-1 (HO-1) is a ubiquitous 32-kDa protein expressed in many tissues and highly inducible. They catalyze the degradation of the heme group and the release of free iron, carbon monoxide, and biliverdin; the latter converted t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ae8cd1ce0a7184d981cda61c755fce2
https://europepmc.org/articles/PMC7153632/
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6
Chronic expression of wild-type Ret receptor in the mammary gland induces luminal tumors that are sensitive to Ret inhibition
Autor: Nancy E. Hynes, Edith C. Kordon, Albana Gattelli, Robert D. Cardiff, Martín E. García Solá, Lewis A. Chodosh, Tim Roloff
Publikováno v: Oncogene. 37:4046-4054
The receptor tyrosine kinase Ret, a key gain-of-function mutated oncoprotein in thyroid carcinomas, has recently been implicated in other cancer types. While Ret copy number gains and mutations have been reported at low frequencies in breast tumors,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed733e3dd0215671087977c354a3a5ff
https://doi.org/10.1038/s41388-018-0235-y
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7
Abstract 5041: Inhibition of RUNX-CBFβ binding reduces RSPO3 expression and EMT features in breast cancer cells
Autor: Lucio H. Castilla, Martín E García Solá, Carla M. Felcher, Edith C. Kordon, John H. Bushweller, Johanna M. Tocci
Publikováno v: Cancer Research. 80:5041-5041
We have recently identified R-spondin3 (RSPO3) as a novel key modulator of breast cancer development that may become a potential target for treatment of the basal subtype, which lacks efficient therapeutic options to date. RSPO3 is expressed in the b
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d1c7e6e6543c19c0c30b44472224e9b7
https://doi.org/10.1158/1538-7445.am2020-5041
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8
Abstract 3685: Sustained Ret expression during mammary gland post-lactation induces premature involution and enhances cancer potential
Autor: Nancy E. Hynes, Lewis A. Chodosh, Edith C. Kordon, Robert D. Cardiff, Roberto Meiss, Carolina Shere-Levy, Albana Gattelli, Sabrina A. Vallone, Martín E García Solá
Publikováno v: Cancer Research. 80:3685-3685
Loss of normal development is a hallmark of cancer. Thus, understanding the mechanisms of tissue-specific developmental regulation and the changes that occur during tumorigenesis may provide insights of both diagnostic and therapeutic importance. In
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::14ec0f5ed4a296c4ccae1c53fa138673
https://doi.org/10.1158/1538-7445.am2020-3685
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9
R-spondin3 Is Associated with Basal-Progenitor Behavior in Normal and Tumor Mammary Cells
Autor: Omar A. Coso, Anabella Srebrow, Roberto Meiss, Johanna M. Tocci, Edith C. Kordon, Martín E García Solá, María Victoria Goddio, Natalia Rubinstein, Carla M. Felcher, María Noel Zimberlin, Martín Carlos Abba
Publikováno v: SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
R-spondin3 (RSPO3) is a member of a family of secreted proteins that enhance Wnt signaling pathways in diverse processes, including cancer. However, the role of RSPO3 in mammary gland and breast cancer development remains unclear. In this study, we s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19e465e6ac047a82af1a0e5a270a96a7
http://sedici.unlp.edu.ar/handle/10915/124844
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10
Akademický článek
PTHrP induces STAT5 activation, secretory differentiation and accelerates mammary tumor development
Autor: Diego Y. Grinman, Kata Boras-Granic, Farzin M. Takyar, Pamela Dann, Julie R. Hens, Christina Marmol, Jongwon Lee, Jungmin Choi, Lewis A. Chodosh, Martin E. Garcia Sola, John J. Wysolmerski
Publikováno v: Breast Cancer Research, Vol 24, Iss 1, Pp 1-23 (2022)
Abstract Background Parathyroid hormone-related protein (PTHrP) is required for embryonic breast development and has important functions during lactation, when it is produced by alveolar epithelial cells and secreted into the maternal circulation to
Externí odkaz: https://doaj.org/article/0866506a580944328c436ede225ea652
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