Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Marshall W Hogarth"'
Effect of endurance exercise on microRNAs in myositis skeletal muscle-A randomized controlled study.
Autor:
Jessica F Boehler, Marshall W Hogarth, Matthew D Barberio, James S Novak, Svetlana Ghimbovschi, Kristy J Brown, Li Alemo Munters, Ingela Loell, Yi-Wen Chen, Heather Gordish-Dressman, Helene Alexanderson, Ingrid E Lundberg, Kanneboyina Nagaraju
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183292 (2017)
To identify changes in skeletal muscle microRNA expression after endurance exercise and associate the identified microRNAs with mRNA and protein expression to disease-specific pathways in polymyositis (PM) and dermatomyositis (DM) patients.Following
Externí odkaz:
https://doaj.org/article/d90075eef8b740c6bdb09916a05214c1
Autor:
Marshall W. Hogarth, Aurelia Defour, Christopher Lazarski, Eduard Gallardo, Jordi Diaz Manera, Terence A. Partridge, Kanneboyina Nagaraju, Jyoti K. Jaiswal
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Fibroadipogenic precursor cells (FAPs) contribute to fibrosis and adipogenic replacement in muscular dystrophies. Here, the authors show that FAPs contribute to adipogenic loss in mouse models of limb girdle muscular dystrophy 2B via a mechanism depe
Externí odkaz:
https://doaj.org/article/0de39a40d2af49bb9bb31819d111a9f9
Autor:
James S. Novak, Marshall W. Hogarth, Jessica F. Boehler, Marie Nearing, Maria C. Vila, Raul Heredia, Alyson A. Fiorillo, Aiping Zhang, Yetrib Hathout, Eric P. Hoffman, Jyoti K. Jaiswal, Kanneboyina Nagaraju, Sebahattin Cirak, Terence A. Partridge
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Exon skipping is a strategy for the treatment of Duchenne muscular dystrophy, but has variable efficacy. Here, the authors show that dystrophin restoration occurs preferentially in areas of myofiber regeneration, where antisense oligonucleotides are
Externí odkaz:
https://doaj.org/article/2bba740be75c451786064cc88308d9ee
Autor:
Marshall W. Hogarth, Peter J. Houweling, Kristen C. Thomas, Heather Gordish-Dressman, Luca Bello, Cooperative International Neuromuscular Research Group (CINRG), Elena Pegoraro, Eric P. Hoffman, Stewart I. Head, Kathryn N. North
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Duchenne muscular dystrophy is a disease caused by a single gene, characterized by progressive muscle weakness, but is variable between patients partly due to interactions of other genes. Here, the authors show that a commonACTN3polymorphism can modi
Externí odkaz:
https://doaj.org/article/818c34e56abe46399fd41cf88d337f97
Autor:
Valentina Debattisti, Adam Horn, Raghavendra Singh, Erin L. Seifert, Marshall W. Hogarth, Davi A. Mazala, Kai Ting Huang, Rita Horvath, Jyoti K. Jaiswal, György Hajnóczky
Publikováno v:
Cell Reports, Vol 29, Iss 5, Pp 1274-1286.e6 (2019)
Summary: Muscle function is regulated by Ca2+, which mediates excitation-contraction coupling, energy metabolism, adaptation to exercise, and sarcolemmal repair. Several of these actions rely on Ca2+ delivery to the mitochondrial matrix via the mitoc
Externí odkaz:
https://doaj.org/article/701195f520d343c5a1569669fb45b003
Autor:
Gerald Coulis, Diego Jaime, Christian Guerrero-Juarez, Jenna M. Kastenschmidt, Philip K. Farahat, Quy Nguyen, Nicholas Pervolarakis, Katherine McLinden, Lauren Thurlow, Saba Movahedi, Jorge Duarte, Andrew Sorn, Elizabeth Montoya, Izza Mozaffar, Morgan Dragan, Shivashankar Othy, Trupti Joshi, Chetan P. Hans, Virginia Kimonis, Adam L. MacLean, Qing Nie, Lindsay M. Wallace, Scott Q. Harper, Tahseen Mozaffar, Marshall W. Hogarth, Surajit Bhattacharya, Jyoti K. Jaiswal, David R. Golann, Qi Su, Kai Kessenbrock, Michael Stec, Melissa J. Spencer, Jesse R. Zamudio, S. Armando Villalta
Publikováno v:
bioRxiv
The monocytic/macrophage system is essential for skeletal muscle homeostasis, but its dysregulation contributes to the pathogenesis of muscle degenerative disorders. Despite our increasing knowledge of the role of macrophages in degenerative disease,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e5353e2ada6cb20a8b3fd8cc1d6f1fe
https://doi.org/10.1101/2023.04.18.537253
https://doi.org/10.1101/2023.04.18.537253
Publikováno v:
Trends in Molecular Medicine. 28:8-11
Aside from myofibers, numerous mononucleated cells reside in the skeletal muscle. These include the mesenchymal cells called fibro-adipogenic progenitors (FAPs), that support muscle development and regeneration in adult muscles. Recent evidence shows
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f59a03aed71efc2968189b523f6c221e
https://doi.org/10.1016/j.molmed.2021.10.003
https://doi.org/10.1016/j.molmed.2021.10.003
Autor:
James S. Novak, Marshall W. Hogarth, Jessica F. Boehler, Marie Nearing, Maria C. Vila, Raul Heredia, Alyson A. Fiorillo, Aiping Zhang, Yetrib Hathout, Eric P. Hoffman, Jyoti K. Jaiswal, Kanneboyina Nagaraju, Sebahattin Cirak, Terence A. Partridge
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
The originally published version of this Article contained an error in Figure 6. In panel b, the top graph (BrdU 21–24d) and the bottom graph (BrdU 28–31d) were inadvertently swapped. This error has now been corrected in both the PDF and HTML ver
Externí odkaz:
https://doaj.org/article/a9e3c5af6e8f42de973b74b8f858aefb
Autor:
Katie A. Edwards, James S. Novak, Kanneboyina Nagaraju, Qi Long Lu, Margaret Benny Klimek, Jessica F. Boehler, Bonnie Douglas, Yi-Wen Chen, Melissa Morales, Ning Li, Maria Candida Vila, Davi A. G. Mázala, Yetrib Hathout, John van den Anker, Eric P. Hoffman, Alyson A. Fiorillo, Alexander G. Fritz, Terence A. Partridge, Marshall W. Hogarth, Travis B. Kinder, Aiping Zhang
Publikováno v:
J Pathol
Exon skipping is a promising genetic therapeutic strategy for restoring dystrophin expression in the treatment of Duchenne muscular dystrophy (DMD). The potential for newly synthesized dystrophin to trigger an immune response in DMD patients, however
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82d88880d71c9fdce29503a7ff16d24c
https://doi.org/10.1002/path.5263
https://doi.org/10.1002/path.5263
TGF-β–driven muscle degeneration and failed regeneration underlie disease onset in a DMD mouse model
Autor:
Christopher B. Tully, James S. Novak, Terence A. Partridge, Prabhat Adusumalli, Yi-Wen Chen, Davi A. G. Mázala, Nayab F. Habib, Marie Nearing, Marshall W. Hogarth, Jyoti K. Jaiswal, Heather Gordish-Dressman
Publikováno v:
JCI Insight
Duchenne muscular dystrophy (DMD) is a chronic muscle disease characterized by poor myogenesis and replacement of muscle by extracellular matrix. Despite the shared genetic basis, severity of these deficits varies among patients. One source of these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a898dfc8c2026bb8ef6d91ece4680c0
https://doi.org/10.1172/jci.insight.135703
https://doi.org/10.1172/jci.insight.135703