Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Marshall G. Frazer"'
Publikováno v:
Journal of Maternal-Fetal and Neonatal Medicine. 1:177-180
Endothelin-1 is a potent vasoconstrictor peptide released by vascular endothelial cells. Preeclampsia is a unique hypertensive disorder of pregnancy. Endothelial (ET) cell injury has been implicated in the pathophysiology of this disorder. Endothelia
Autor:
Kazumoto Iijima, Tomoh Masaki, Marshall G. Frazer, Lang Lin, Masashi Yanagisawa, Kamal F. Badr, Michael S. Goligorsky, Alberto Nasjletti, Maureen A. Morgan, Frederick J. Kaskel
Publikováno v:
Journal of Cardiovascular Pharmacology. 17:S484-491
To evaluate the possible role of endothelin in the development and/or maintenance of hypertension in Dahl rats, we examined the responsiveness of isolated vascular smooth muscle and glomerular mesangial cells, as well as deendothelialized vascular ri
Autor:
Robert J. Deegan, Margaret Wood, Alastair J. J. Wood, Richard Nelson, C. Michael Stein, Tadashi Inagami, Kamal F. Badr, Marshall G. Frazer, Huaibing He
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 25(6)
Abstract In vitro and limited in vivo data suggest that rapid desensitization of β-adrenoceptor responses occurs after exposure to agonist. Tachyphylaxis to a β-adrenoceptor agonist would represent a potentially important mechanism for the short-te
Publikováno v:
Hepatology (Baltimore, Md.). 18(4)
Autoradiographic studies have shown that the liver accumulates endothelin. High-affinity binding sites for endothelin have been identified on rat liver plasma membranes. We investigated the role of endothelin isopeptides as mediators of cholestasis w
Publikováno v:
The New England journal of medicine. 327(25)
Severe renal vasoconstriction is central to the pathogenesis of renal failure in the hepatorenal syndrome. Endothelin-1 and endothelin-3 are potent, long-acting vasoconstrictors, and endothelin-1 has selective potency as a renal vasoconstrictor. Thes
Autor:
Kenneth L. Brigham, Marshall G. Frazer, Jeffrey E. Hazlewood, Masanori Okamoto, Barbara Meyrick, Robert J. Workman
Publikováno v:
Blood. 66:1379-1383
Whether migration of granulocytes across pulmonary vascular endothelium in the absence of structural evidence of endothelial injury causes increased production of thromboxane or prostacyclin is not known. Using bovine pulmonary artery intimal explant
Autor:
Marshall G. Frazer, Hollifield Jw
Publikováno v:
Clinical Biochemistry. 13:34-37
The organic acids potassium hydrogen phthalate (KHphthalate), maleic, critic, acetic, formic, and oxalic were used to adjust the pH of plasma to 5.6 +/- 0.2 in the incubation step of the procedure for the determination of plasma renin activity (PRA).
Autor:
Donald E. Pearson, Marshall G. Frazer
Publikováno v:
Clinical Biochemistry. 14:94-97
(1) In order to explore the possible mechanism that organic reagents used in the incubation step of the plasma renin activity (PRA) analysis act as angiotensinase inhibitors we did angiotensin I (AI) recovery studies from plasma with such reagents. T
Autor:
Marshall G. Frazer, Donald E. Pearson
Publikováno v:
Clinica Chimica Acta. 105:117-122
The tris(hydroxymethyl)aminomethane salts of the organic acids acetylsalicylic, phenoxyacetic, salicylic, benzoic, acetic, and maleic were used to buffer the pH of plasma between 7.4 and 7.7 in a 1 h incubation step of the procedure for the determina
Publikováno v:
The Journal of Organic Chemistry. 37:358-362