Zobrazeno 1 - 10
of 483
pro vyhledávání: '"Marshall, GM"'
BACKGROUND: The cost of socioeconomic inequality in health service use among Australian children with chronic health conditions is poorly understood. OBJECTIVES: To quantify the cost of socioeconomic inequality in health service use among Australian
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::d470f0652f5b3ca6dddf5c7e9f82e693
https://hdl.handle.net/10453/166066
https://hdl.handle.net/10453/166066
Autor:
Chen, J, Nelson, C, Wong, M, Tee, AE, Liu, PY, La, T, Fletcher, JI, Kamili, A, Mayoh, C, Bartenhagen, C, Trahair, TN, Xu, N, Jayatilleke, N, Peng, H, Atmadibrata, B, Cheung, BB, Lan, Q, Bryan, TM, Mestdagh, P, Vandesompele, J, Combaret, V, Boeva, V, Wang, JY, Janoueix-Lerosey, I, Cowley, MJ, MacKenzie, KL, Dolnikov, A, Li, J, Polly, P, Marshall, GM, Reddel, RR, Norris, MD, Haber, M, Fischer, M, Zhang, XD, Pickett, HA, Liu, T
PurposeTERT gene rearrangement with transcriptional superenhancers leads to TERT overexpression and neuroblastoma. No targeted therapy is available for clinical trials in patients with TERT-rearranged neuroblastoma.Experimental designAnticancer agent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::e304684dc45deac0e7292e9fe1f60923
https://hdl.handle.net/10453/148374
https://hdl.handle.net/10453/148374
Autor:
Tee, AE, Ciampa, OC, Wong, M, Fletcher, JI, Kamili, A, Chen, J, Ho, N, Sun, Y, Carter, DR, Cheung, BB, Marshall, GM, Liu, PY, Liu, T
Patients with neuroblastoma due to MYCN oncogene amplification and consequent N-Myc oncoprotein overexpression have very poor prognosis. The cyclin-dependent kinase 7 (CDK7)/super-enhancer inhibitor THZ1 suppresses MYCN gene transcription, reduces ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::b75aefb39f03d33a9c833c730d5822d8
https://hdl.handle.net/10453/143977
https://hdl.handle.net/10453/143977
© 2019, The Author(s). Purpose: The tripartite motif (TRIM)16 acts as a tumour suppressor in both squamous cell carcinoma (SCC) and melanoma. TRIM16 is known to be secreted by keratinocytes, but no studies have been reported yet to assess the relati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::ed0b74baa71b6f2aa183057333bdaabf
https://hdl.handle.net/10453/138259
https://hdl.handle.net/10453/138259
Autor:
Ooi, CY, Carter, DR, Liu, B, Mayoh, C, Beckers, A, Lalwani, A, Nagy, Z, De Brouwer, S, Decaesteker, B, Hung, TT, Norris, MD, Haber, M, Liu, T, De Preter, K, Speleman, F, Cheung, BB, Marshall, GM
© 2018 American Association for Cancer Research. Neuroblastoma is a pediatric cancer of the sympathetic nervous system where MYCN amplification is a key indicator of poor prognosis. However, mechanisms by which MYCN promotes neuroblastoma tumorigene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::3e6e8935f80c67c2dc5be9ff6480f4d2
https://hdl.handle.net/10453/133116
https://hdl.handle.net/10453/133116
Autor:
Dorneburg, C, Fischer, M, Barth, TFE, Mueller-Klieser, W, Hero, B, Gecht, J, Carter, DR, de Preter, K, Mayer, B, Christner, L, Speleman, F, Marshall, GM, Debatin, KM, Beltinger, C
© 2018 American Association for Cancer Research. Purpose: To investigate whether lactate dehydrogenase A (LDHA), an important component of the LDH tetramer crucial for aerobic glycolysis, is associated with patient outcome and constitutes a therapeu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::4d8bc160803f67c7eefe1fbdd7d19068
https://hdl.handle.net/10453/133058
https://hdl.handle.net/10453/133058
Autor:
Sutton, SK, Carter, DR, Kim, P, Tan, O, Arndt, GM, Zhang, XD, Baell, J, Noll, BD, Wang, S, Kumar, N, McArthur, GA, Cheung, BB, Marshall, GM
There is an urgent need for better therapeutic options for advanced melanoma patients, particularly those without the BRAFV600E/K mutation. In melanoma cells, loss of TRIM16 expression is a marker of cell migration and metastasis, while the BRAF inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::056173978bd980eb10e8d76f29c82777
https://hdl.handle.net/10453/159919
https://hdl.handle.net/10453/159919
Glutathione biosynthesis is upregulated at the initiation of MYCN-driven neuroblastoma tumorigenesis
Autor:
Carter, DR, Sutton, SK, Pajic, M, Murray, J, Sekyere, EO, Fletcher, J, Beckers, A, De Preter, K, Speleman, F, George, RE, Haber, M, Norris, MD, Cheung, BB, Marshall, GM
The MYCN gene is amplified and overexpressed in a large proportion of high stage neuroblastoma patients and has been identified as a key driver of tumorigenesis. However, the mechanism by which MYCN promotes tumor initiation is poorly understood. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::9f267bbbbb04d3f0e9411f369da78b18
https://hdl.handle.net/10453/159921
https://hdl.handle.net/10453/159921
Background: We assessed the risk of developing second malignancies in children treated for Hodgkin's lymphoma (HL), the majority of whom received chemotherapy only.Patients and methods: The development of second malignancies in children with HL, trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::ba0990c07a641e4c981b23df5ef60717
https://hdl.handle.net/10453/113159
https://hdl.handle.net/10453/113159
Autor:
Marshall, Gm, Liu, Py, Gherardi, S, Scarlett, Cj, Bedalov, A, Xu, N, Iraci, Nunzio, Mackenzie, Kl, Haber, M, Norris, Md, Biankin, Av, Perini, G, Liu, T.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______4731::2b07f2186a184bff2b5b91ae70d61d27
http://hdl.handle.net/20.500.11769/247709
http://hdl.handle.net/20.500.11769/247709