Zobrazeno 1 - 10
of 238
pro vyhledávání: '"Marschall S, Runge"'
Autor:
Aleksandr E. Vendrov, Andrey Lozhkin, Takayuki Hayami, Julia Levin, Jamille Silveira Fernandes Chamon, Ahmed Abdel-Latif, Marschall S. Runge, Nageswara R. Madamanchi
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionAging increases the risk of atherosclerotic vascular disease and its complications. Macrophages are pivotal in the pathogenesis of vascular aging, driving inflammation and atherosclerosis progression. NOX4 (NADPH oxidase 4) expression inc
Externí odkaz:
https://doaj.org/article/97421a6ff6ab4ef4b790e27bfcceab63
Autor:
Aleksandr E. Vendrov, Han Xiao, Andrey Lozhkin, Takayuki Hayami, Guomin Hu, Matthew J. Brody, Junichi Sadoshima, You-Yi Zhang, Marschall S. Runge, Nageswara R. Madamanchi
Publikováno v:
Redox Biology, Vol 67, Iss , Pp 102937- (2023)
In acute sympathetic stress, catecholamine overload can lead to stress cardiomyopathy. We tested the hypothesis that cardiomyocyte NOX4 (NADPH oxidase 4)-dependent mitochondrial oxidative stress mediates inflammation and diastolic dysfunction in stre
Externí odkaz:
https://doaj.org/article/3c1a6afa2f4b4816ba1bb6bf16cdd07c
Autor:
Roberto Ramos-Mondragón, Andrey Lozhkin, Aleksandr E. Vendrov, Marschall S. Runge, Lori L. Isom, Nageswara R. Madamanchi
Publikováno v:
Antioxidants, Vol 12, Iss 10, p 1833 (2023)
Atrial fibrillation (AF) is the most common type of cardiac arrhythmia and its prevalence increases with age. The irregular and rapid contraction of the atria can lead to ineffective blood pumping, local blood stasis, blood clots, ischemic stroke, an
Externí odkaz:
https://doaj.org/article/e3407661e46b4a829b9b7196e0ad1637
Autor:
Andrey Lozhkin, Aleksandr E. Vendrov, R. Ramos-Mondragón, Chandrika Canugovi, Mark D. Stevenson, Todd J. Herron, Scott L. Hummel, C Alberto Figueroa, Dawn E. Bowles, Lori L. Isom, Marschall S. Runge, Nageswara R. Madamanchi
Publikováno v:
Redox Biology, Vol 57, Iss , Pp 102474- (2022)
Diastolic dysfunction (DD) underlies heart failure with preserved ejection fraction (HFpEF), a clinical syndrome associated with aging that is becoming more prevalent. Despite extensive clinical studies, no effective treatment exists for HFpEF. Recen
Externí odkaz:
https://doaj.org/article/dc83512223294a7ca072f2906aa86579
Autor:
Roberto Ramos-Mondragon, Nnamdi Edokobi, Samantha L. Hodges, Shuyun Wang, Alexandra A. Bouza, Chandrika Canugovi, Caroline Scheuing, Lena Juratli, William R. Abel, Sami F. Noujaim, Nageswara R. Madamanchi, Marschall S. Runge, Luis F. Lopez-Santiago, Lori L. Isom
Publikováno v:
JCI Insight, Vol 7, Iss 10 (2022)
Loss-of-function (LOF) variants in SCN1B, encoding the voltage-gated sodium channel β1/β1B subunits, are linked to neurological and cardiovascular diseases. Scn1b-null mice have spontaneous seizures and ventricular arrhythmias and die by approximat
Externí odkaz:
https://doaj.org/article/d5c4382c17d04144bec174f8c5eb54a6
Autor:
Mark D. Stevenson, Aleksandr E. Vendrov, Xi Yang, Yuenmu Chen, Hernán A. Navarro, Nicholas Moss, Marschall S. Runge, William J. Arendshorst, Nageswara R. Madamanchi
Publikováno v:
American Journal of Physiology-Renal Physiology. 324:F335-F352
Renal reactivity to angiotensin II (ANG II) is mediated by superoxide signaling produced by NADPH oxidase (NOX)A1/NOX1. Acute vasoconstriction of renal arteries by ANG was blunted in Noxa1−/− compared with wild-type mice. NOXA1/NOX1/O2•− sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4facfabfcb3097e8424b9bc87e7927aa
https://doi.org/10.1152/ajprenal.00236.2022
https://doi.org/10.1152/ajprenal.00236.2022
Autor:
Guomin, Hu, Jimin, Wu, Huijun, Gu, Xiangning, Deng, Wenli, Xu, Shan, Feng, Shuaixing, Wang, Yao, Song, Zhengda, Pang, Xiuling, Deng, Aleksandr E, Vendrov, Nageswara R, Madamanchi, Marschall S, Runge, Xinyu, Wang, Youyi, Zhang, Han, Xiao, Erdan, Dong
Publikováno v:
Science China Life Sciences. 66:1067-1078
Rapid over-activation of β-adrenergic receptors (β-AR) following acute stress initiates cardiac inflammation and injury by activating interleukin-18 (IL-18), however, the process of inflammation cascades has not been fully illustrated. The present
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2de285ab6671e3060e144cbe0216d4e9
https://doi.org/10.1007/s11427-022-2189-x
https://doi.org/10.1007/s11427-022-2189-x
Autor:
Chandrika Canugovi, Mark D. Stevenson, Aleksandr E. Vendrov, Takayuki Hayami, Jacques Robidoux, Han Xiao, You-Yi Zhang, Daniel T. Eitzman, Marschall S. Runge, Nageswara R. Madamanchi
Publikováno v:
Redox Biology, Vol 26, Iss , Pp - (2019)
Aging is characterized by increased aortic stiffness, an early, independent predictor and cause of cardiovascular disease. Oxidative stress from excess reactive oxygen species (ROS) production increases with age. Mitochondria and NADPH oxidases (NOXs
Externí odkaz:
https://doaj.org/article/b8c1df8409b84504910d37bbb75f0f0e
Autor:
Aleksandr E. Vendrov, Arihiro Sumida, Chandrika Canugovi, Andrey Lozhkin, Takayuki Hayami, Nageswara R. Madamanchi, Marschall S. Runge
Publikováno v:
Redox Biology, Vol 21, Iss , Pp - (2019)
Increased reactive oxygen species (ROS) production and inflammation are key factors in the pathogenesis of atherosclerosis. We previously reported that NOX activator 1 (NOXA1) is the critical functional homolog of p67phox for NADPH oxidase activation
Externí odkaz:
https://doaj.org/article/46ebe320d2cc4821bc3448d2ca2a7940
Autor:
Elena Mironova, Crystal R. Archer, Aleksandr E. Vendrov, Marschall S. Runge, Nageswara R. Madamanchi, William J. Arendshorst, James D. Stockand, Tarek Mohamed Abd El-Aziz
Publikováno v:
American journal of physiology. Renal physiology. 323(6)
Activity of the epithelial Na+ channel (ENaC) in the distal nephron fine-tunes renal Na+ excretion. Angiotensin II (ANG II) has been reported to enhance ENaC activity. Emerging evidence suggests that NADPH oxidase (NOX) signaling plays an important r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::253428199a3cfbae1ac195c5a07e12a5
https://pubmed.ncbi.nlm.nih.gov/36201326
https://pubmed.ncbi.nlm.nih.gov/36201326