A Fusion Protein Complex that Combines IL-12, IL-15, and IL-18 Signaling to Induce Memory-Like NK Cells for Cancer Immunotherapy.

Autor: Becker-Hapak MK; Washington University School of Medicine, Division of Oncology, Saint Louis, Missouri., Shrestha N; HCW Biologics Inc., Miramar, Florida., McClain E; Washington University School of Medicine, Division of Oncology, Saint Louis, Missouri., Dee MJ; HCW Biologics Inc., Miramar, Florida., Chaturvedi P; HCW Biologics Inc., Miramar, Florida., Leclerc GM; HCW Biologics Inc., Miramar, Florida., Marsala LI; Washington University School of Medicine, Division of Oncology, Saint Louis, Missouri., Foster M; Washington University School of Medicine, Division of Oncology, Saint Louis, Missouri., Schappe T; Washington University School of Medicine, Division of Oncology, Saint Louis, Missouri., Tran J; Washington University School of Medicine, Division of Oncology, Saint Louis, Missouri., Desai S; Washington University School of Medicine, Division of Oncology, Saint Louis, Missouri., Neal CC; Washington University School of Medicine, Division of Oncology, Saint Louis, Missouri., Pence P; Washington University School of Medicine, Division of Oncology, Saint Louis, Missouri., Wong P; Washington University School of Medicine, Division of Oncology, Saint Louis, Missouri., Wagner JA; Washington University School of Medicine, Division of Oncology, Saint Louis, Missouri., Russler-Germain DA; Washington University School of Medicine, Division of Oncology, Saint Louis, Missouri., Zhu X; HCW Biologics Inc., Miramar, Florida., Spanoudis CM; HCW Biologics Inc., Miramar, Florida., Gallo VL; HCW Biologics Inc., Miramar, Florida., Echeverri CA; HCW Biologics Inc., Miramar, Florida., Ramirez LL; HCW Biologics Inc., Miramar, Florida., You L; HCW Biologics Inc., Miramar, Florida., Egan JO; HCW Biologics Inc., Miramar, Florida., Rhode PR; HCW Biologics Inc., Miramar, Florida., Jiao JA; HCW Biologics Inc., Miramar, Florida., Muniz GJ; HCW Biologics Inc., Miramar, Florida., Jeng EK; HCW Biologics Inc., Miramar, Florida., Prendes CA; HCW Biologics Inc., Miramar, Florida., Sullivan RP; Wugen, Inc., Saint Louis, Missouri., Berrien-Elliott MM; Washington University School of Medicine, Division of Oncology, Saint Louis, Missouri., Wong HC; HCW Biologics Inc., Miramar, Florida., Fehniger TA; Washington University School of Medicine, Division of Oncology, Saint Louis, Missouri. tfehnige@wustl.edu.

Publikováno v: Cancer immunology research [Cancer Immunol Res] 2021 Sep; Vol. 9 (9), pp. 1071-1087. Date of Electronic Publication: 2021 Jul 09.