Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Mars G, Sharapov"'
Publikováno v:
Reviews in Cardiovascular Medicine, Vol 25, Iss 8, p 295 (2024)
This review summarises the data from long-term experimental studies and literature data on the role of oxidatively modified low-density lipoproteins (LDL) in atherogenesis and diabetogenesis. It was shown that not “oxidized” (lipoperoxide-contain
Externí odkaz:
https://doaj.org/article/844d8504a1e2472ca458692820769e09
Autor:
Elena G. Novoselova, Olga V. Glushkova, Sergey M. Lunin, Maxim O. Khrenov, Svetlana B. Parfenyuk, Tatyana V. Novoselova, Mars G. Sharapov, Vladimir I. Novoselov, Evgeny E. Fesenko
Publikováno v:
Journal of Diabetes Research, Vol 2020 (2020)
Type 1 diabetes is associated with the destruction of pancreatic beta cells, which is mediated via an autoimmune mechanism and consequent inflammatory processes. In this article, we describe a beneficial effect of peroxiredoxin 6 (PRDX6) in a type 1
Externí odkaz:
https://doaj.org/article/182ccb597a9c4da79dbf9e5c9605cbfb
Autor:
Elena G. Novoselova, Mars G. Sharapov, Sergey M. Lunin, Svetlana B. Parfenyuk, Maxim O. Khrenov, Elvira K. Mubarakshina, Anna A. Kuzekova, Tatyana V. Novoselova, Ruslan G. Goncharov, Olga V. Glushkova
Publikováno v:
Antioxidants, Vol 10, Iss 12, p 1951 (2021)
Although many different classes of antioxidants have been evaluated as radioprotectors, none of them are in widespread clinical use because of their low efficiency. The goal of our study was to evaluate the potential of the antioxidant protein peroxi
Externí odkaz:
https://doaj.org/article/4181a92dcdcc4cd38c2e39f110f07f5a
Autor:
Ekaterina E. Karmanova, Anatoly V. Chernikov, Nelli R. Popova, Mars G. Sharapov, Vladimir E. Ivanov, Vadim I. Bruskov
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b17d1ab19f6827f53a87c322886ffb8
https://doi.org/10.1007/s00210-023-02466-w
https://doi.org/10.1007/s00210-023-02466-w
Autor:
Mars G. Sharapov, Ruslan G. Goncharov, Gleb I. Filkov, Alexander V. Trofimenko, Valery V. Boyarintsev, Vladimir I. Novoselov
Publikováno v:
Antioxidants, Vol 9, Iss 8, p 680 (2020)
The pathogenesis of ischemia-reperfusion (I/R) injuries is based on oxidative stress caused by a sharp increase in the concentration of free radicals, reactive oxygen species (ROS) and secondary products of free radical oxidation of biological macrom
Externí odkaz:
https://doaj.org/article/4356c93f06fc49269fea6c9c0e9d7473
Publikováno v:
Biochemistry (Moscow). 86:1256-1274
The review presents current concepts of the molecular mechanisms of oxidative stress development and describes main stages of the free-radical reactions in oxidative stress. Endogenous and exogenous factors of the oxidative stress development, includ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2787b1a9607472ed426f44848cb9b248
https://doi.org/10.1134/s0006297921100084
https://doi.org/10.1134/s0006297921100084
Autor:
Mars G. Sharapov, Ruslan G. Goncharov, Svetlana B. Parfenyuk, Olga V. Glushkova, Vladimir I. Novoselov
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 23; Pages: 15265
Peroxiredoxin 6 (Prdx6) is a multifunctional eukaryotic antioxidant enzyme. Mammalian Prdx6 possesses peroxidase activity against a wide range of organic and inorganic hydroperoxides, as well as exhibits phospholipase A2 (aiPLA2) activity, which play
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::020a13a43cf2a360e555d3b91897572b
https://pubmed.ncbi.nlm.nih.gov/36499590
https://pubmed.ncbi.nlm.nih.gov/36499590
Publikováno v:
Biochemistry. Biokhimiia. 87(8)
Peroxiredoxin 6 (Prdx6) is an important antioxidant enzyme with multiple functions in the cell. Prdx6 neutralizes a wide range of hydroperoxides, participates in phospholipid metabolism and cell membrane repair, and in transmission of intracellular a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d517bb56f830e99a1d18daaf27954d3
https://pubmed.ncbi.nlm.nih.gov/36171649
https://pubmed.ncbi.nlm.nih.gov/36171649
Autor:
Ningfei Shen, Xiaoli Qi, Dmitry V. Bagrov, Sergey P. Krechetov, Mars G. Sharapov, Mikhail O. Durymanov
Publikováno v:
Colloids and surfaces. B, Biointerfaces. 219
Modification of the cell surface with artificial nano- and microparticles (also termed "cellular backpacks") containing biologically active payloads usually enables drug targeting via harnessing intrinsic cell tropism to the sites of injury. In some
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d650b4e0f1b3826c37823aa0f533fa3
https://pubmed.ncbi.nlm.nih.gov/36152599
https://pubmed.ncbi.nlm.nih.gov/36152599
Publikováno v:
Antioxidants, Vol 8, Iss 1, p 15 (2019)
Peroxiredoxin 6 (Prdx6) is a member of an evolutionary ancient family of peroxidase enzymes with diverse functions in the cell. Prdx6 is an important enzymatic antioxidant. It reduces a wide range of peroxide substrates in the cell, thus playing a le
Externí odkaz:
https://doaj.org/article/fa539e86fb1e404cbbc5a4b628e88fe7