Retention of Ag-specific memory CD4 ⁺ T cells in the draining lymph node indicates lymphoid tissue resident memory populations.

Autor: Marriott CL; Institute of Immunology & Immunotherapy, College of Medical and Dental Sciences, University of Birmingham, UK., Dutton EE; Institute of Immunology & Immunotherapy, College of Medical and Dental Sciences, University of Birmingham, UK., Tomura M; Laboratory of Immunology, Faculty of Pharmacy, Osaka-Ohtani University 3-11-1 Nishikiorikita, Tondabayashi-city, Osaka prefecture, Japan., Withers DR; Institute of Immunology & Immunotherapy, College of Medical and Dental Sciences, University of Birmingham, UK.

Publikováno v: European journal of immunology [Eur J Immunol] 2017 May; Vol. 47 (5), pp. 860-871. Date of Electronic Publication: 2017 Apr 11.

Transient inhibition of ROR-γt therapeutically limits intestinal inflammation by reducing TH17 cells and preserving group 3 innate lymphoid cells.

Autor: Withers DR; MRC Centre for Immune Regulation, Institute of Immunology and Immunotherapy, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK., Hepworth MR; Joan and Sanford I. Weill Department of Medicine, Gastroenterology Division, Weill Cornell Medicine, New York, New York, USA.; Department of Microbiology and Immunology, Weill Cornell Medicine, New York, New York, USA.; The Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, New York, New York, USA., Wang X; Joan and Sanford I. Weill Department of Medicine, Gastroenterology Division, Weill Cornell Medicine, New York, New York, USA.; Department of Microbiology and Immunology, Weill Cornell Medicine, New York, New York, USA.; The Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, New York, New York, USA., Mackley EC; MRC Centre for Immune Regulation, Institute of Immunology and Immunotherapy, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK., Halford EE; MRC Centre for Immune Regulation, Institute of Immunology and Immunotherapy, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK., Dutton EE; MRC Centre for Immune Regulation, Institute of Immunology and Immunotherapy, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK., Marriott CL; MRC Centre for Immune Regulation, Institute of Immunology and Immunotherapy, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK., Brucklacher-Waldert V; Babraham Institute, Babraham Research Campus, Cambridge, UK., Veldhoen M; Babraham Institute, Babraham Research Campus, Cambridge, UK., Kelsen J; Division of Gastroenterology, Hepatology and Nutrition, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Baldassano RN; Division of Gastroenterology, Hepatology and Nutrition, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Sonnenberg GF; Joan and Sanford I. Weill Department of Medicine, Gastroenterology Division, Weill Cornell Medicine, New York, New York, USA.; Department of Microbiology and Immunology, Weill Cornell Medicine, New York, New York, USA.; The Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, New York, New York, USA.

Publikováno v: Nature medicine [Nat Med] 2016 Mar; Vol. 22 (3), pp. 319-23. Date of Electronic Publication: 2016 Feb 15.

CCR7-dependent trafficking of RORγ⁺ ILCs creates a unique microenvironment within mucosal draining lymph nodes.

Autor: Mackley EC; MRC Centre for Immune Regulation, Institute for Biomedical Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, UK., Houston S; Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow G12 8TA, UK., Marriott CL; MRC Centre for Immune Regulation, Institute for Biomedical Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, UK., Halford EE; MRC Centre for Immune Regulation, Institute for Biomedical Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, UK., Lucas B; MRC Centre for Immune Regulation, Institute for Biomedical Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, UK., Cerovic V; Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow G12 8TA, UK., Filbey KJ; Institute of Immunology and Infection Research, University of Edinburgh, Edinburgh EH9 3FL, UK., Maizels RM; Institute of Immunology and Infection Research, University of Edinburgh, Edinburgh EH9 3FL, UK., Hepworth MR; 1] Division of Gastroenterology, Joan and Sanford I. Weill Department of Medicine, New York, New York 10021, USA [2] The Jill Robert's Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medical College, New York, New York 10021, USA., Sonnenberg GF; 1] Division of Gastroenterology, Joan and Sanford I. Weill Department of Medicine, New York, New York 10021, USA [2] The Jill Robert's Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medical College, New York, New York 10021, USA [3] Department of Microbiology and Immunology, The Jill Robert's Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medical College, New York, New York 10021, USA., Milling S; Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow G12 8TA, UK., Withers DR; MRC Centre for Immune Regulation, Institute for Biomedical Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, UK.

Publikováno v: Nature communications [Nat Commun] 2015 Jan 09; Vol. 6, pp. 5862. Date of Electronic Publication: 2015 Jan 09.

CLEC-2 is required for development and maintenance of lymph nodes.

Autor: Bénézech C; School of Immunity and Infection and., Nayar S; School of Immunity and Infection and., Finney BA; Centre for Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom., Withers DR; School of Immunity and Infection and., Lowe K; Centre for Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom., Desanti GE; School of Immunity and Infection and., Marriott CL; School of Immunity and Infection and., Watson SP; Centre for Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom., Caamaño JH; School of Immunity and Infection and., Buckley CD; School of Immunity and Infection and., Barone F; School of Immunity and Infection and.

Publikováno v: Blood [Blood] 2014 May 15; Vol. 123 (20), pp. 3200-7. Date of Electronic Publication: 2014 Feb 14.

Extended multilocus variable-number tandem-repeat analysis of Clostridium difficile correlates exactly with ribotyping and enables identification of hospital transmission.

Autor: Manzoor SE; School of Infection and Immunity, University of Birmingham, Birmingham B15 2TT, United Kingdom., Tanner HE, Marriott CL, Brazier JS, Hardy KJ, Platt S, Hawkey PM

Publikováno v: Journal of clinical microbiology [J Clin Microbiol] 2011 Oct; Vol. 49 (10), pp. 3523-30. Date of Electronic Publication: 2011 Aug 17.