A new schedule of one week on/one week off temozolomide as second-line treatment of advanced neuroendocrine carcinomas (TENEC-TRIAL): a multicenter, open-label, single-arm, phase II trial.

Autor: von Arx C; Department of Breast and Thoracic Oncology, Division of Breast Medical Oncology, Istituto Nazionale Tumori IRCCS 'Fondazione G. Pascale', Naples. Electronic address: claudia.vonarx@istitutotumori.na.it., Della Vittoria Scarpati G; Sarcomas and Rare Tumors Unit, Istituto Nazionale Tumori - I.R.C.C.S. Fondazione 'G.Pascale', Naples., Cannella L; Sarcomas and Rare Tumors Unit, Istituto Nazionale Tumori - I.R.C.C.S. Fondazione 'G.Pascale', Naples., Clemente O; Sarcomas and Rare Tumors Unit, Istituto Nazionale Tumori - I.R.C.C.S. Fondazione 'G.Pascale', Naples., Marretta AL; Medical Oncology Unit, Ospedale Ave Gratia Plena, San Felice a Cancello, Caserta., Bracigliano A; Nuclear Medicine, Istituto Nazionale Tumori - I.R.C.C.S. Fondazione 'G. Pascale', Naples., Picozzi F; Sarcomas and Rare Tumors Unit, Istituto Nazionale Tumori - I.R.C.C.S. Fondazione 'G.Pascale', Naples., Iervolino D; ISS Clinica di Domenico Iervolino, Palma Campania, Naples., Granata V; Radiology Unit, Istituto Nazionale Tumori - I.R.C.C.S. Fondazione 'G. Pascale', Naples., Modica R; Endocrinology, Diabetology and Andrology Unit, Department of Clinical Medicine and Surgery, Federico II University of Naples, Naples., Bianco A; Medical Oncology Unit AORN Ospedale dei Colli, Naples., Mocerino C; Medical Oncology Unit AORN 'A. Cardarelli', Naples., Di Mauro A; Pathology Unit, Istituto Nazionale Tumori - I.R.C.C.S. Fondazione 'G. Pascale', Naples., Pizzolorusso A; Sarcomas and Rare Tumors Unit, Istituto Nazionale Tumori - I.R.C.C.S. Fondazione 'G.Pascale', Naples., Di Sarno A; Endocrinology, Diabetology and Andrology Unit, Department of Clinical Medicine and Surgery, Federico II University of Naples, Naples., Ottaiano A; SSD Innovative Therapies for Abdominal Metastases, Abdominal Oncology, Istituto Nazionale Tumori di Napoli, IRCCS 'G. Pascale', Naples, Italy., Tafuto S; Sarcomas and Rare Tumors Unit, Istituto Nazionale Tumori - I.R.C.C.S. Fondazione 'G.Pascale', Naples.

Publikováno v: ESMO open [ESMO Open] 2024 May; Vol. 9 (5), pp. 103003. Date of Electronic Publication: 2024 Apr 13.

The Impact of O6-Methylguanine-DNA Methyltransferase ( MGMT ) Promoter Methylation on the Outcomes of Patients with Leiomyosarcoma Treated with Dacarbazine.

Autor: Cannella L; S.C. Sarcomi e Tumori Rari, Istituto Nazionale Tumori-IRCCS-Fondazione 'G. Pascale', 80131 Naples, Italy., Della Monica R; CEINGE-Biotecnologie Avanzate, 80131 Naples, Italy., Marretta AL; Department of Clinical and Surgery Oncology Unit, University of Naples 'Federico II', 80131 Naples, Italy., Iervolino D; S.C. Anatomia Patologica, IsIstituto Nazionale Tumori-IRCCS-Fondazione 'G. Pascale', 80131 Naples, Italy., Vincenzi B; Dipartimento di Oncologia Medica, Campus Bio-Medico University, 00168 Rome, Italy., De Chiara AR; S.S.D Istopatologia dei Linfomi e dei Sarcomi, Istituto Nazionale Tumori-IRCCS-Fondazione 'G. Pascale', 80131 Naples, Italy., Clemente O; S.C. Sarcomi e Tumori Rari, Istituto Nazionale Tumori-IRCCS-Fondazione 'G. Pascale', 80131 Naples, Italy., Buonaiuto M; CEINGE-Biotecnologie Avanzate, 80131 Naples, Italy., Barretta ML; S.C. Radiologia, Istituto Nazionale Tumori-IRCCS-Fondazione 'G. Pascale', 80131 Naples, Italy., Di Mauro A; S.C. Anatomia Patologica, IsIstituto Nazionale Tumori-IRCCS-Fondazione 'G. Pascale', 80131 Naples, Italy., Di Marzo M; S.C. Chirurgia Addominale, Istituto Nazionale Tumori-IRCCS-Fondazione 'G. Pascale', 80131 Naples, Italy., Guida M; Unità Tumori Rari e Melanoma, IRCCS Istituto Tumori 'Giovanni Paolo II', Viale O. Flacco, 65, 70124 Bari, Italy., Badalamenti G; Department of Surgical, Oncological and Oral Sciences, Section of Medical Oncology, University of Palermo, 90129 Palermo, Italy., Chiariotti L; CEINGE-Biotecnologie Avanzate, 80131 Naples, Italy., Tafuto S; S.C. Sarcomi e Tumori Rari, Istituto Nazionale Tumori-IRCCS-Fondazione 'G. Pascale', 80131 Naples, Italy.

Publikováno v: Cells [Cells] 2023 Jun 15; Vol. 12 (12). Date of Electronic Publication: 2023 Jun 15.

Assessment of Total, PTEN ^- , and AR-V7 ⁺ Circulating Tumor Cell Count by Flow Cytometry in Patients with Metastatic Castration-Resistant Prostate Cancer Receiving Enzalutamide.

Autor: Di Lorenzo G; Department of Clinical Medicine and Surgery, University Federico II of Naples, Naples, Italy; Department of Medicine and Health Sciences 'Vincenzo Tiberio,' University of Molise, Campobasso, Italy; Department of Oncology, Hospital 'Andrea Tortora,' ASL Salerno, Pagani, Italy; Department of Oncology and Hematology, AOU Federico II of Naples, Naples, Italy., Zappavigna S; Department of Precision Medicine, University of Campania 'L. Vanvitelli,' Naples, Italy., Crocetto F; Department of Neurosciences, Human Reproduction and Odontostomatology, University of Naples Federico II, Naples, Italy., Giuliano M; Department of Clinical Medicine and Surgery, University Federico II of Naples, Naples, Italy; Regional Reference Center for Rare Tumors, Department of Oncology and Hematology, AOU Federico II of Naples, Naples, Italy., Ribera D; Department of Clinical Medicine and Surgery, University Federico II of Naples, Naples, Italy., Morra R; Department of Clinical Medicine and Surgery, University Federico II of Naples, Naples, Italy., Scafuri L; Department of Clinical Medicine and Surgery, University Federico II of Naples, Naples, Italy., Verde A; Department of Clinical Medicine and Surgery, University Federico II of Naples, Naples, Italy., Bruzzese D; Department of Public Health, University of Naples 'Federico II,' Naples, Italy., Iaccarino S; Department of Clinical Medicine and Surgery, University Federico II of Naples, Naples, Italy., Costabile F; Department of Clinical Medicine and Surgery, University Federico II of Naples, Naples, Italy., Onofrio L; Department of Clinical Medicine and Surgery, University Federico II of Naples, Naples, Italy., Viggiani M; Department of Clinical Medicine and Surgery, University Federico II of Naples, Naples, Italy., Palmieri A; Department of Neurosciences, Human Reproduction and Odontostomatology, University of Naples Federico II, Naples, Italy., De Placido P; Department of Clinical Medicine and Surgery, University Federico II of Naples, Naples, Italy., Marretta AL; Department of Clinical Medicine and Surgery, University Federico II of Naples, Naples, Italy., Pietroluongo E; Department of Clinical Medicine and Surgery, University Federico II of Naples, Naples, Italy., Luce A; Department of Precision Medicine, University of Campania 'L. Vanvitelli,' Naples, Italy., Abate M; Department of Precision Medicine, University of Campania 'L. Vanvitelli,' Naples, Italy., Navaeiseddighi Z; Department of Precision Medicine, University of Campania 'L. Vanvitelli,' Naples, Italy., Caputo VF; Department of Neurosciences, Human Reproduction and Odontostomatology, University of Naples Federico II, Naples, Italy., Celentano G; Department of Neurosciences, Human Reproduction and Odontostomatology, University of Naples Federico II, Naples, Italy., Longo N; Department of Neurosciences, Human Reproduction and Odontostomatology, University of Naples Federico II, Naples, Italy., Ferro M; Division of Urology, European Institute of Oncology-IRCCS, Milan, Italy., Morelli F; Medical Oncology Unit, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy., Facchini G; Departmental Unit of Experimental Uro-Andrological Clinical Oncology, Department of Uro-Gynaecological Oncology, National Cancer Institute-IRCCS-G. Pascale Foundation, Naples, Italy., Caraglia M; Department of Precision Medicine, University of Campania 'L. Vanvitelli,' Naples, Italy; Biogem Scarl, Institute of Genetic Research, Laboratory of Precision Medicine and Molecular Oncology, Ariano Irpino, Italy., De Placido S; Department of Clinical Medicine and Surgery, University Federico II of Naples, Naples, Italy; Regional Reference Center for Rare Tumors, Department of Oncology and Hematology, AOU Federico II of Naples, Naples, Italy., Buonerba C; Department of Clinical Medicine and Surgery, University Federico II of Naples, Naples, Italy; Regional Reference Center for Rare Tumors, Department of Oncology and Hematology, AOU Federico II of Naples, Naples, Italy. Electronic address: carlo.buonerba@unina.it.

Publikováno v: Clinical genitourinary cancer [Clin Genitourin Cancer] 2021 Oct; Vol. 19 (5), pp. e286-e298. Date of Electronic Publication: 2021 Apr 03.

Impact of COVID-19 outbreak on cancer immunotherapy in Italy: a survey of young oncologists.

Autor: Ottaviano M; Oncology Unit, Ospedale del Mare, Napoli, Campania, Italy.; Department of Clinical Medicine and Surgery, Università degli Studi di Napoli Federico II and CRCTR Coordinating Rare Tumors Reference Center of Campania Region, AOU Federico II, Napoli, Italy., Curvietto M; Unit of Melanoma, Cancer Immunotherapy and Development Therapeutics, Istituto Nazionale Tumori IRCCS Fondazione Pascale, Napoli, Campania, Italy., Rescigno P; Clinical Studies, The Institute of Cancer Research and the Royal Marsden NHS Foundation Trust, London, UK., Tortora M; CRCTR Coordinating Rare Tumors Reference Center of Campania Region, AOU Federico II, Napoli, Campania, Italy., Palmieri G; CRCTR Coordinating Rare Tumors Reference Center of Campania Region, AOU Federico II, Napoli, Campania, Italy., Giannarelli D; Biostatistics Unit, IRCCS Regina Elena National Cancer Institute, Roma, Lazio, Italy., Aieta M; Medical Oncology Unit, Department of Onco-Hematology, IRCCS-CROB Referral Cancer Center of Basilicata, Rionero in Vulture, Basilicata, Italy., Assalone P; Oncology Unit, Ospedale Ferdinando Veneziale, Isernia, Molise, Italy., Attademo L; Department of Urology and Gynecology, Istituto Nazionale Tumori IRCCS Fondazione Pascale, Napoli, Campania, Italy., Avallone A; Abdominal Oncology Unit, Istituto Nazionale Tumori IRCCS Fondazione Pascale, Napoli, Campania, Italy., Bloise F; Medical Oncology Unit, University of Pisa, Pisa, Toscana, Italy., Bosso D; Oncology Unit, Ospedale del Mare, Napoli, Italy., Borzillo V; Department of Radioterapia, Istituto Nazionale Tumori IRCCS Fondazione Pascale, Napoli, Campania, Italy., Buono G; Oncology Unit, San Rocco Hospital, Sessa Aurunca, Campania, Italy., Calderoni G; Oncology Unit, Ospedale Della Murgia, Bari, Puglia, Italy., Caputo F; U.O.C. Oncologia, Azienda Ospedaliera dei Colli, Monaldi Hospital, Napoli, Campania, Italy., Cartenì G; Department of Medical Oncology, AORN 'A. Cardarelli', Napoli, Campania, Italy., Cavallero D; Medical Oncology Unit, University of Pisa, Pisa, Toscana, Italy., Cavo A; Oncology Unit, Villa Scassi Hospital, Genova, Italy., Ciardiello F; Oncology, Department of Precision Medicine, Università della Campania 'L. Vanvitelli', Napoli, Campania, Italy., Conca R; Medical Oncology Unit, Department of Onco-Hematology, IRCCS-CROB Referral Cancer Center of Basilicata, Rionero in Vulture, Basilicata, Italy., Conteduca V; Medical Oncology Department, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola, Emilia-Romagna, Italy., De Falco S; Oncology Unit, Sant'Ottone Frangipane Hospital, Avellino, Campania, Italy., De Felice M; Oncology, Department of Precision Medicine, Università della Campania 'L. Vanvitelli', Napoli, Campania, Italy.; Oncology Unit, Sant'Anna e San Sebastiano, Caserta, Campania, Italy., De Laurentiis M; Breast Unit, Istituto Nazionale Tumori IRCCS Fondazione Pascale, Napoli, Campania, Italy., De Placido P; Department of Clinical Medicine and Surgery, Oncology Unit, Università degli Studi di Napoli Federico II, Napoli, Campania, Italy., De Placido S; CRCTR Coordinating Rare Tumors Reference Center of Campania Region, AOU Federico II, Napoli, Campania, Italy.; Department of Clinical Medicine and Surgery, Oncology Unit, Università degli Studi di Napoli Federico II, Napoli, Campania, Italy., De Santo I; Oncology Unit, Gemelli Molise s.p.a, Campobasso, Molise, Italy., De Stefano A; Abdominal Oncology Unit, Istituto Nazionale Tumori IRCCS Fondazione Pascale, Napoli, Campania, Italy., Della Corte CM; Oncology, Department of Precision Medicine, Università della Campania 'L. Vanvitelli', Napoli, Campania, Italy., Di Franco R; Department of Radioterapia, Istituto Nazionale Tumori IRCCS Fondazione Pascale, Napoli, Campania, Italy., Di Lauro V; Breast Unit, Istituto Nazionale Tumori IRCCS Fondazione Pascale, Napoli, Campania, Italy.; Department of Clinical Medicine and Surgery, Oncology Unit, Università degli Studi di Napoli Federico II, Napoli, Campania, Italy., Fabbrocini A; Oncology Unit, Ospedale del Mare, Napoli, Italy., Federico P; Oncology Unit, Ospedale del Mare, Napoli, Italy., Festino L; Unit of Melanoma, Cancer Immunotherapy and Development Therapeutics, Istituto Nazionale Tumori IRCCS Fondazione Pascale, Napoli, Campania, Italy., Giordano P; Oncology Unit, Ospedale del Mare, Napoli, Italy., Giuliano M; CRCTR Coordinating Rare Tumors Reference Center of Campania Region, AOU Federico II, Napoli, Campania, Italy.; Department of Clinical Medicine and Surgery, Oncology Unit, Università degli Studi di Napoli Federico II, Napoli, Campania, Italy., Gridelli C; Division of Medical Oncology, 'San Giuseppe Moscati' Hospital, Avellino, Campania, Italy., Grimaldi AM; Unit of Melanoma, Cancer Immunotherapy and Development Therapeutics, Istituto Nazionale Tumori IRCCS Fondazione Pascale, Napoli, Campania, Italy., Lia M; Oncology Unit, SS Antonio e Biagio e Cesare Arrigo Hospital, Alessandria, Piemonte, Italy., Marretta AL; Department of Clinical Medicine and Surgery, Oncology Unit, Università degli Studi di Napoli Federico II, Napoli, Campania, Italy., Massa V; Medical Oncology Unit, University of Pisa, Pisa, Toscana, Italy., Mennitto A; Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Lombardia, Italy., Merler S; Department of Oncology, University of Verona, Verona, Veneto, Italy., Merz V; Department of Medical Oncology, Santa Chiara Hospital, Trento, Trentino Alto Adige, Italy., Messina C; Department of Medical Oncology, Santa Chiara Hospital, Trento, Trentino Alto Adige, Italy., Messina M; UOC Oncologia Medica, Ospedali Riuniti Villa Sofia Cervello, Palermo, Sicilia, Italy., Milano M; Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Lombardia, Italy., Minisini AM; Department of Oncology, Azienda Sanitaria Universitaria Integrata del Friuli Centrale, Udine, Friuli Venezia Giulia, Italy., Montesarchio V; U.O.C. Oncologia, Azienda Ospedaliera dei Colli, Monaldi Hospital, Napoli, Campania, Italy., Morabito A; Thoracic Medical Oncology, Istituto Nazionale Tumori IRCCS Fondazione Pascale, Napoli, Campania, Italy., Morgillo F; Oncology, Department of Precision Medicine, Università della Campania 'L. Vanvitelli', Napoli, Campania, Italy., Mucci B; Department of Clinical Medicine and Surgery, Oncology Unit, Università degli Studi di Napoli Federico II, Napoli, Campania, Italy., Nappi L; Vancouver Prostate Centre, Department of Urologic Sciences, University of British Columbia, Vancouver, BC, Canada and British Columbia Cancer Agency-Vancouver Center-Department of Medicine, Division of Medical Oncology, University of British Columbia, Vancouver, British Columbia, Canada., Napolitano F; Department of Clinical Medicine and Surgery, Oncology Unit, Università degli Studi di Napoli Federico II, Napoli, Campania, Italy., Paciolla I; Oncology Unit, Ospedale Sacro Cuore di Gesù Fatebenefratelli, Benevento, Campania, Italy., Pagliuca M; Department of Clinical Medicine and Surgery, Oncology Unit, Università degli Studi di Napoli Federico II, Napoli, Campania, Italy., Palmieri G; Institute of Research on Genetics and Biomedicine (IRGB), National Research Council (CNR), Sassari, Sardegna, Italy., Parola S; Department of Clinical Medicine and Surgery, Oncology Unit, Università degli Studi di Napoli Federico II, Napoli, Campania, Italy., Pepe S; Department of Medicine, Surgery and Dentistry 'Scuola Medica Salernitana', Oncology Unit, University of Salerno, Baronissi, Campania, Italy., Petrillo A; Oncology Unit, Ospedale del Mare, Napoli, Italy.; Oncology, Department of Precision Medicine, Università della Campania 'L. Vanvitelli', Napoli, Campania, Italy., Piantedosi F; U.O.C. Pneumologia Oncologica, Azienda Ospedaliera dei Colli, Monaldi Hospital, Naples, Campania, Italy., Piccin L; Veneto Institute of Oncology IOV-IRCCS, Padova, Veneto, Italy., Picozzi F; Department of Clinical Medicine and Surgery, Oncology Unit, Università degli Studi di Napoli Federico II, Napoli, Campania, Italy., Pietroluongo E; Department of Clinical Medicine and Surgery, Oncology Unit, Università degli Studi di Napoli Federico II, Napoli, Campania, Italy., Pignata S; Department of Urology and Gynecology, Istituto Nazionale Tumori IRCCS Fondazione Pascale, Napoli, Campania, Italy., Prati V; Medical Oncology Unit, ASL CN2, Alba, Piemonte, Italy., Riccio V; Department of Clinical Medicine and Surgery, Oncology Unit, Università degli Studi di Napoli Federico II, Napoli, Campania, Italy., Rosanova M; Oncology Unit, Ospedale del Mare, Napoli, Italy., Rossi A; Department of Oncology, University of Verona, Verona, Veneto, Italy., Russo A; Medical Oncology Unit, Fondazione IRCCS Giovanni Paolo II, Bari, Puglia, Italy., Salati M; Medical Oncology Unit, University Hospital Modena, Modena, Emilia Romagna, Italy., Santabarbara G; Division of Medical Oncology, 'San Giuseppe Moscati' Hospital, Avellino, Campania, Italy., Sbrana A; Medical Oncology Unit, University of Pisa, Pisa, Toscana, Italy., Simeone E; Unit of Melanoma, Cancer Immunotherapy and Development Therapeutics, Istituto Nazionale Tumori IRCCS Fondazione Pascale, Napoli, Campania, Italy., Silvestri A; Oncology Unit, Ospedale del Mare, Napoli, Italy., Spada M; Oncology Unit, Fondazione Istituto San Raffaele G Giglio di Cefalu, Cefalu, Sicilia, Italy., Tarantino P; Division of Early Drug Development for Innovative Therapies, European Institute of Oncology IRCCS, Milano, Lombardia, Italy., Taveggia P; Oncology Unit, Villa Scassi Hospital, Genova, Italy., Tomei F; Oncology Unit, Ospedale Ferdinando Veneziale, Isernia, Molise, Italy., Vincenzo T; Department of Clinical Medicine and Surgery, Oncology Unit, Università degli Studi di Napoli Federico II, Napoli, Campania, Italy.; Department of Medicine, Surgery and Dentistry 'Scuola Medica Salernitana', Oncology Unit, University of Salerno, Baronissi, Campania, Italy., Trapani D; Division of Early Drug Development for Innovative Therapies, European Institute of Oncology IRCCS, Milano, Lombardia, Italy., Trojanello C; Unit of Melanoma, Cancer Immunotherapy and Development Therapeutics, Istituto Nazionale Tumori IRCCS Fondazione Pascale, Napoli, Campania, Italy., Vanella V; Unit of Melanoma, Cancer Immunotherapy and Development Therapeutics, Istituto Nazionale Tumori IRCCS Fondazione Pascale, Napoli, Campania, Italy., Vari S; Medical Oncology 1 Unit, IRCCS Regina Elena National Cancer Institute, Rome, Lazio, Italy., Ventriglia J; Oncology Division, ASL San Felice a Cancello, Caserta, Campania, Italy., Vitale MG; Unit of Melanoma, Cancer Immunotherapy and Development Therapeutics, Istituto Nazionale Tumori IRCCS Fondazione Pascale, Napoli, Campania, Italy.; Department of Oncology, Azienda Sanitaria Universitaria Integrata del Friuli Centrale, Udine, Friuli Venezia Giulia, Italy., Vitiello F; U.O.C. Pneumologia Oncologica, Azienda Ospedaliera dei Colli, Monaldi Hospital, Naples, Campania, Italy., Vivaldi C; Medical Oncology Unit, University of Pisa, Pisa, Toscana, Italy., von Arx C; Department of Surgery and Cancer, Imperial College, London, UK., Zacchi F; Oncology Unit, Università degli Studi di Verona, sede Borgo Roma, Verona, Veneto, Italy., Zampiva I; Oncology Unit, Università degli Studi di Verona, sede Borgo Roma, Verona, Veneto, Italy., Zivi A; Department of Surgery and Cancer, Imperial College, London, UK.; Medical Oncology Department, AOUI di Verona, Verona, Veneto, Italy., Daniele B; Oncology Unit, Ospedale del Mare, Napoli, Italy., Ascierto PA; Unit of Melanoma, Cancer Immunotherapy and Development Therapeutics, Istituto Nazionale Tumori IRCCS Fondazione Pascale, Napoli, Campania, Italy paolo.ascierto@gmail.com.

Publikováno v: Journal for immunotherapy of cancer [J Immunother Cancer] 2020 Oct; Vol. 8 (2).