Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Maroun J. Beyrouthy"'
Autor:
Michael J. Spinella, Ethan Dmitrovsky, Alan Eastman, Sarah J. Freemantle, Mary P. Hever, Kristen M. Garner, Maroun J. Beyrouthy
Supplementary Table 1 from High DNA Methyltransferase 3B Expression Mediates 5-Aza-Deoxycytidine Hypersensitivity in Testicular Germ Cell Tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddf2a4bfb16b7eb11b4b15b752b97fbb
https://doi.org/10.1158/0008-5472.22382969
https://doi.org/10.1158/0008-5472.22382969
Autor:
Michael J. Spinella, Ethan Dmitrovsky, Alan Eastman, Sarah J. Freemantle, Mary P. Hever, Kristen M. Garner, Maroun J. Beyrouthy
Testicular germ cell tumors (TGCT) are the most common solid tumors of 15- to 35-year-old men. TGCT patients are frequently cured with cytotoxic cisplatin-based therapy. However, TGCT patients refractory to cisplatin-based chemotherapy have a poor pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8dbb8d89ae38c819ad7a39463250a181
https://doi.org/10.1158/0008-5472.c.6500375
https://doi.org/10.1158/0008-5472.c.6500375
Autor:
Bijesh K Biswal, Maroun J Beyrouthy, Mary P Hever-Jardine, David Armstrong, Craig R Tomlinson, Brock C Christensen, Carmen J Marsit, Michael J Spinella
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e53003 (2012)
Human embryonal carcinoma (EC) cells are the stem cells of nonseminoma testicular germ cells tumors (TGCTs) and share remarkable similarities to human embryonic stem (ES) cells. In prior work we found that EC cells are hypersensitive to low nanomolar
Externí odkaz:
https://doaj.org/article/a03afb36e5c4405b938a6654ddcf4d3a
Autor:
Maroun J Beyrouthy, Karen E Alexander, Amy Baldwin, Michael L Whitfield, Hank W Bass, Dan McGee, Myra M Hurt
Publikováno v:
PLoS ONE, Vol 3, Iss 12, p e3943 (2008)
Obtaining synchronous cell populations is essential for cell-cycle studies. Methods such as serum withdrawal or use of drugs which block cells at specific points in the cell cycle alter cellular events upon re-entry into the cell cycle. Regulatory ev
Externí odkaz:
https://doaj.org/article/45439f8ae65846f79f0daa27b6275652
Autor:
Lynne M. Niemaszyk, Esty G. yanco, Damayanti Desai, Michael J. Spinella, Mary P. Hever, Jessica M. Haghkerdar, Sarah J. Freemantle, Joanna S. Kerley-Hamilton, Pingping Mao, Maroun J. Beyrouthy
Publikováno v:
Journal of Biological Chemistry. 286:19381-19391
Testicular cancer is highly curable with cisplatin-based therapy, and testicular cancer-derived human embryonal carcinoma (EC) cells undergo a p53-dominant transcriptional response to cisplatin. In this study, we have discovered that a poorly charact
Autor:
Regine Kraft, Anja Krippner-Heidenreich, Bernhard Lüscher, Myra M. Hurt, Gesa Walsemann, Maroun J. Beyrouthy, Robert V. Talanian, Hubert Thole, Stefanie Speckgens
Publikováno v:
Molecular and Cellular Biology. 25:3704-3714
The transcriptional regulator Yin Yang 1 (YY1) controls many aspects of cell behavior and is essential for development. We analyzed the fate of YY1 during apoptosis and studied the functional consequences. We observed that this factor is rapidly tran
Autor:
Carmen J. Marsit, David A. Armstrong, Craig R. Tomlinson, Michael J. Spinella, Mary P. Hever-Jardine, Maroun J. Beyrouthy, Brock C. Christensen, Bijesh K. Biswal
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 12, p e53003 (2012)
PLoS ONE, Vol 7, Iss 12, p e53003 (2012)
Human embryonal carcinoma (EC) cells are the stem cells of nonseminoma testicular germ cells tumors (TGCTs) and share remarkable similarities to human embryonic stem (ES) cells. In prior work we found that EC cells are hypersensitive to low nanomolar
Autor:
Sarah J. Freemantle, Mary P. Hever, Maroun J. Beyrouthy, Alan Eastman, Ethan Dmitrovsky, Michael J. Spinella, Kristen M. Garner
Publikováno v:
Cancer research. 69(24)
Testicular germ cell tumors (TGCT) are the most common solid tumors of 15- to 35-year-old men. TGCT patients are frequently cured with cytotoxic cisplatin-based therapy. However, TGCT patients refractory to cisplatin-based chemotherapy have a poor pr
Autor:
Daniel L. McGee, Amy Baldwin, Karen E. Alexander, Michael L. Whitfield, Myra M. Hurt, Maroun J. Beyrouthy, Hank W. Bass
Publikováno v:
PLoS ONE, Vol 3, Iss 12, p e3943 (2008)
PLoS ONE
PLoS ONE
Background Obtaining synchronous cell populations is essential for cell-cycle studies. Methods such as serum withdrawal or use of drugs which block cells at specific points in the cell cycle alter cellular events upon re-entry into the cell cycle. Re
Publikováno v:
The FASEB Journal. 22