Prospective multicentre study of host response signatures in neonatal sepsis in Sub Saharan Africa

Autor: Sem Ezinmegnon, Marine Mommert, Francois Bartolo, Gino Agbota, Sossou Darius, Valérie Briand, Marceline d’Almeida, Maroufou Jules Alao, Ida Dossou-Dagba, Achille Massougbodji, Ulrik Lausten-Thomsen, Alexandre Pachot, Laurence Vachot, Javier Yugueros-Marcos, Karen Brengel-Pesce, Nadine Fievet, Pierre Tissieres

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)

Abstract Few biomarkers for sepsis diagnosis are commonly used in neonatal sepsis. While the role of host response is increasingly recognized in sepsis pathogenesis and prognosis, there is a need for evaluating new biomarkers targeting host response

Externí odkaz: https://doaj.org/article/06908d35f39347ee84d93a98a5e784de

Lead Exposure in Infancy and Subsequent Growth in Beninese Children

Autor: Shukrullah Ahmadi, Jérémie Botton, Roméo Zoumenou, Pierre Ayotte, Nadine Fievet, Achille Massougbodji, Maroufou Jules Alao, Michel Cot, Philippe Glorennec, Florence Bodeau-Livinec

Publikováno v: Toxics, Vol 10, Iss 10, p 595 (2022)

Studies suggest that elevated postnatal blood lead levels (BLLs) are negatively associated with child growth. This study aimed to investigate the associations of childhood BLLs at age one year and growth outcomes at age six years (n = 661) in a cohor

Externí odkaz: https://doaj.org/article/71f8cda6dd434be390076e7050459a0f

Elevated plasma IL-8 as a risk factor for mortality in children presenting with cerebral malaria (NeuroCM study)

Autor: Jade Royo, Bertin Vianou, Manfred Accrombessi, Elisée Kinkpé, Linda Ayédadjou, Ida Dossou-Dagba, Yélé Ladipo, Maroufou Jules Alao, Gwladys I Bertin, Michel Cot, Farid Boumediene, Sandrine Houzé, Jean-François Faucher, Agnès Aubouy, collaborators NeuroCM group

Background: Cerebral malaria (CM) is a neuropathology which remains one of the deadliest forms of malaria among African children. The kinetics of the pathophysiological mechanisms leading to neuroinflammation and the death or survival of patients dur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f3a57883c78e18fa1fb2d98da6315e81
https://doi.org/10.21203/rs.3.rs-2276410/v1

IgG acquisition against PfEMP1 PF11_0521 domain cassette DC13, DBLβ3_D4 domain, and peptides located within these constructs in children with cerebral malaria

Autor: Badaut, Cyril, Visitdesotrakul, Pimnitah, Chabry, Aurelie, Bigey, Pascal, Tornyigah, Bernard, Roman, Jocelyne, Maroufou, Jules Alao, Amoussou, Annick, Ayivi, Blaise Serge, Sagbo, Gratien, Ndam, Nicaise Tuikue, Oleinikov, Andrew V., Tahar, Rachida

Publikováno v: Scientific Reports
Scientific Reports, Nature Publishing Group, 2021, 11 (1), ⟨10.1038/s41598-021-82444-5⟩
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports, 2021, 11 (1), ⟨10.1038/s41598-021-82444-5⟩

International audience; The Plasmodium falciparum erythrocyte-membrane-protein-1 (PF3D7_1150400/PF11_0521) contains both domain cassette DC13 and DBL beta 3 domain binding to EPCR and ICAM-1 receptors, respectively. This type of PfEMP1 proteins with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a561552f32bf1c00865585c0625fab93
http://europepmc.org/articles/PMC7878510

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