Wastewater sequencing reveals early cryptic SARS-CoV-2 variant transmission.

Autor: Karthikeyan S; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Levy JI; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., De Hoff P; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA.; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, La Jolla, CA, USA.; COVID-19 Detection, Investigation, Surveillance, Clinical, and Outbreak Response, California Department of Public Health, Richmond, CA, USA., Humphrey G; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Birmingham A; Center for Computational Biology and Bioinformatics, University of California San Diego, La Jolla, CA, USA., Jepsen K; Institute for Genomic Medicine, University of California San Diego, La Jolla, CA, USA., Farmer S; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Tubb HM; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Valles T; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Tribelhorn CE; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Tsai R; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Aigner S; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Sathe S; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Moshiri N; Department of Computer Science and Engineering, University of California San Diego, La Jolla, CA, USA., Henson B; Institute for Genomic Medicine, University of California San Diego, La Jolla, CA, USA., Mark AM; Center for Computational Biology and Bioinformatics, University of California San Diego, La Jolla, CA, USA., Hakim A; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA.; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, La Jolla, CA, USA.; COVID-19 Detection, Investigation, Surveillance, Clinical, and Outbreak Response, California Department of Public Health, Richmond, CA, USA., Baer NA; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Barber T; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Belda-Ferre P; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Chacón M; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Cheung W; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA.; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, La Jolla, CA, USA.; COVID-19 Detection, Investigation, Surveillance, Clinical, and Outbreak Response, California Department of Public Health, Richmond, CA, USA., Cresini ES; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Eisner ER; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Lastrella AL; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Lawrence ES; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Marotz CA; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Ngo TT; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Ostrander T; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Plascencia A; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Salido RA; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Seaver P; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Smoot EW; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., McDonald D; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Neuhard RM; Operational Strategic Initiatives, University of California San Diego, La Jolla, CA, USA.; Return to Learn, University of California San Diego, La Jolla, CA, USA., Scioscia AL; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, La Jolla, CA, USA.; Student Health and Well-Being, University of California San Diego, La Jolla, CA, USA., Satterlund AM; Student Affairs, University of California San Diego, La Jolla, CA, USA., Simmons EH; Academic Affairs, University of California San Diego, La Jolla, CA, USA., Abelman DB; Return to Learn, University of California San Diego, La Jolla, CA, USA., Brenner D; Return to Learn, University of California San Diego, La Jolla, CA, USA., Bruner JC; Return to Learn, University of California San Diego, La Jolla, CA, USA., Buckley A; Return to Learn, University of California San Diego, La Jolla, CA, USA., Ellison M; Return to Learn, University of California San Diego, La Jolla, CA, USA., Gattas J; Return to Learn, University of California San Diego, La Jolla, CA, USA., Gonias SL; Department of Pathology, University of California San Diego, La Jolla, CA, USA., Hale M; Return to Learn, University of California San Diego, La Jolla, CA, USA., Hawkins F; Return to Learn, University of California San Diego, La Jolla, CA, USA., Ikeda L; Return to Learn, University of California San Diego, La Jolla, CA, USA., Jhaveri H; Return to Learn, University of California San Diego, La Jolla, CA, USA., Johnson T; Return to Learn, University of California San Diego, La Jolla, CA, USA., Kellen V; Return to Learn, University of California San Diego, La Jolla, CA, USA., Kremer B; Return to Learn, University of California San Diego, La Jolla, CA, USA., Matthews G; Return to Learn, University of California San Diego, La Jolla, CA, USA., McLawhon RW; Return to Learn, University of California San Diego, La Jolla, CA, USA., Ouillet P; Return to Learn, University of California San Diego, La Jolla, CA, USA., Park D; Return to Learn, University of California San Diego, La Jolla, CA, USA., Pradenas A; Return to Learn, University of California San Diego, La Jolla, CA, USA., Reed S; Return to Learn, University of California San Diego, La Jolla, CA, USA., Riggs L; Return to Learn, University of California San Diego, La Jolla, CA, USA., Sanders A; Return to Learn, University of California San Diego, La Jolla, CA, USA., Sollenberger B; Return to Learn, University of California San Diego, La Jolla, CA, USA., Song A; Operational Strategic Initiatives, University of California San Diego, La Jolla, CA, USA.; Return to Learn, University of California San Diego, La Jolla, CA, USA., White B; Return to Learn, University of California San Diego, La Jolla, CA, USA., Winbush T; Return to Learn, University of California San Diego, La Jolla, CA, USA., Aceves CM; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Anderson C; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Gangavarapu K; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Hufbauer E; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Kurzban E; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Lee J; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Matteson NL; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Parker E; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Perkins SA; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Ramesh KS; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Robles-Sikisaka R; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Schwab MA; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Spencer E; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Wohl S; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Nicholson L; Scripps Health, San Diego, La Jolla, CA, USA., McHardy IH; Scripps Health, San Diego, La Jolla, CA, USA., Dimmock DP; Rady Children's Institute for Genomic Medicine, San Diego, CA, USA., Hobbs CA; Rady Children's Institute for Genomic Medicine, San Diego, CA, USA., Bakhtar O; Sharp Healthcare, San Diego, CA, USA., Harding A; Sharp Healthcare, San Diego, CA, USA., Mendoza A; Sharp Healthcare, San Diego, CA, USA., Bolze A; Helix, San Mateo, CA, USA., Becker D; Helix, San Mateo, CA, USA., Cirulli ET; Helix, San Mateo, CA, USA., Isaksson M; Helix, San Mateo, CA, USA., Schiabor Barrett KM; Helix, San Mateo, CA, USA., Washington NL; Helix, San Mateo, CA, USA., Malone JD; County of San Diego Health and Human Services Agency, San Diego, CA, USA., Schafer AM; County of San Diego Health and Human Services Agency, San Diego, CA, USA., Gurfield N; County of San Diego Health and Human Services Agency, San Diego, CA, USA., Stous S; County of San Diego Health and Human Services Agency, San Diego, CA, USA., Fielding-Miller R; Herbert Wertheim School of Public Health and Human Longevity Science, University of California San Diego, La Jolla, CA, USA.; Division of Infectious Disease and Global Public Health, University of California San Diego, La Jolla, CA, USA., Garfein RS; Herbert Wertheim School of Public Health and Human Longevity Science, University of California San Diego, La Jolla, CA, USA., Gaines T; Division of Infectious Disease and Global Public Health, University of California San Diego, La Jolla, CA, USA., Anderson C; Herbert Wertheim School of Public Health and Human Longevity Science, University of California San Diego, La Jolla, CA, USA., Martin NK; Division of Infectious Disease and Global Public Health, University of California San Diego, La Jolla, CA, USA., Schooley R; Division of Infectious Disease and Global Public Health, University of California San Diego, La Jolla, CA, USA., Austin B; Sharp Healthcare, San Diego, CA, USA., MacCannell DR; Office of Advanced Molecular Detection, Centers for Disease Control and Prevention, Atlanta, GA, USA., Kingsmore SF; Rady Children's Institute for Genomic Medicine, San Diego, CA, USA., Lee W; Helix, San Mateo, CA, USA., Shah S; County of San Diego Health and Human Services Agency, San Diego, CA, USA., McDonald E; County of San Diego Health and Human Services Agency, San Diego, CA, USA., Yu AT; COVID-19 Detection, Investigation, Surveillance, Clinical, and Outbreak Response, California Department of Public Health, Richmond, CA, USA., Zeller M; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Fisch KM; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, La Jolla, CA, USA.; Center for Computational Biology and Bioinformatics, University of California San Diego, La Jolla, CA, USA., Longhurst C; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA.; Department of Biomedical Informatics, University of California San Diego, La Jolla, CA, USA., Maysent P; Office of the UC San Diego Health CEO, University of California San Diego, La Jolla, CA, USA., Pride D; Department of Pathology, University of California San Diego, La Jolla, CA, USA.; Department of Medicine, University of California San Diego, La Jolla, CA, USA., Khosla PK; Department of Computer Science and Engineering, University of California San Diego, La Jolla, CA, USA., Laurent LC; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA.; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, La Jolla, CA, USA.; Sanford Consortium of Regenerative Medicine, University of California San Diego, La Jolla, CA, USA., Yeo GW; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA.; Sanford Consortium of Regenerative Medicine, University of California San Diego, La Jolla, CA, USA.; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA., Andersen KG; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Knight R; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA. robknight@ucsd.edu.; Department of Computer Science and Engineering, University of California San Diego, La Jolla, CA, USA. robknight@ucsd.edu.; Department of Bioengineering, University of California San Diego, La Jolla, CA, USA. robknight@ucsd.edu.

Publikováno v: Nature [Nature] 2022 Sep; Vol. 609 (7925), pp. 101-108. Date of Electronic Publication: 2022 Jul 07.

Analysis of SARS-CoV-2 RNA Persistence across Indoor Surface Materials Reveals Best Practices for Environmental Monitoring Programs.

Autor: Salido RA; Department of Bioengineering, University of California San Diego, La Jolla, California, USA., Cantú VJ; Department of Bioengineering, University of California San Diego, La Jolla, California, USA., Clark AE; Division of Infectious Diseases and Global Public Health, Department of Medicine, University of California San Diego School of Medicine, La Jolla, California, USA., Leibel SL; Department of Pediatrics, University of California San Diego, La Jolla, California, USA.; Sanford Consortium of Regenerative Medicine, University of California San Diego, La Jolla, California, USA., Foroughishafiei A; Department of Bioengineering, University of California San Diego, La Jolla, California, USA., Saha A; Department of Bioengineering, University of California San Diego, La Jolla, California, USA., Hakim A; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA., Nouri A; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA., Lastrella AL; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA., Castro-Martínez A; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA., Plascencia A; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA., Kapadia BK; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA., Xia B; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA., Ruiz CA; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA., Marotz CA; Department of Pediatrics, University of California San Diego, La Jolla, California, USA.; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA., Maunder D; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA., Lawrence ES; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA., Smoot EW; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA., Eisner E; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA., Crescini ES; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA., Kohn L; Herbert Wertheim School of Public Health, University of California, La Jolla, California, USA., Franco Vargas L; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA., Chacón M; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA., Betty M; Department of Pediatrics, University of California San Diego, La Jolla, California, USA.; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA.; Rady Children's Hospital, San Diego, California, USA., Machnicki M; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA., Wu MY; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA., Baer NA; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA., Belda-Ferre P; Department of Pediatrics, University of California San Diego, La Jolla, California, USA.; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA., De Hoff P; Sanford Consortium of Regenerative Medicine, University of California San Diego, La Jolla, California, USA.; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA.; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, La Jolla, California, USA., Seaver P; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA., Ostrander RT; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA., Tsai R; Department of Pediatrics, University of California San Diego, La Jolla, California, USA.; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA., Sathe S; Sanford Consortium of Regenerative Medicine, University of California San Diego, La Jolla, California, USA.; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA.; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, California, USA., Aigner S; Sanford Consortium of Regenerative Medicine, University of California San Diego, La Jolla, California, USA.; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA.; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, California, USA., Morgan SC; Sanford Consortium of Regenerative Medicine, University of California San Diego, La Jolla, California, USA.; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, La Jolla, California, USA., Ngo TT; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA., Barber T; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA., Cheung W; Sanford Consortium of Regenerative Medicine, University of California San Diego, La Jolla, California, USA.; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA.; San Diego State University, San Diego, California, USA., Carlin AF; Division of Infectious Diseases and Global Public Health, Department of Medicine, University of California San Diego School of Medicine, La Jolla, California, USA., Yeo GW; Sanford Consortium of Regenerative Medicine, University of California San Diego, La Jolla, California, USA.; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, California, USA., Laurent LC; Sanford Consortium of Regenerative Medicine, University of California San Diego, La Jolla, California, USA.; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, La Jolla, California, USA., Fielding-Miller R; Herbert Wertheim School of Public Health, University of California, La Jolla, California, USA., Knight R; Department of Bioengineering, University of California San Diego, La Jolla, California, USA.; Department of Pediatrics, University of California San Diego, La Jolla, California, USA.; Department of Computer Science and Engineering, University of California San Diego, La Jolla, California, USA.; Center for Microbiome Innovation, Jacobs School of Engineering, University of California San Diego, La Jolla, California, USA.

Publikováno v: MSystems [mSystems] 2021 Dec 21; Vol. 6 (6), pp. e0113621. Date of Electronic Publication: 2021 Nov 02.

Context-aware dimensionality reduction deconvolutes gut microbial community dynamics.

Autor: Martino C; Center for Microbiome Innovation, University of California San Diego, La Jolla, CA, USA.; Bioinformatics and Systems Biology Program, University of California San Diego, La Jolla, CA, USA.; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Shenhav L; Department of Computer Science, University of California Los Angeles, Los Angeles, CA, USA., Marotz CA; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Armstrong G; Bioinformatics and Systems Biology Program, University of California San Diego, La Jolla, CA, USA.; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., McDonald D; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Vázquez-Baeza Y; Center for Microbiome Innovation, University of California San Diego, La Jolla, CA, USA.; Jacobs School of Engineering, University of California San Diego, La Jolla, CA, USA., Morton JT; Center for Computational Biology, Flatiron Institute, Simons Foundation, New York, NY, USA., Jiang L; Division of Biostatistics, University of California San Diego, La Jolla, CA, USA., Dominguez-Bello MG; Department of Biochemistry and Microbiology, Rutgers University New Brunswick, New Brunswick, NJ, USA.; Department of Anthropology, Rutgers University, New Brunswick, NJ, USA., Swafford AD; Center for Microbiome Innovation, University of California San Diego, La Jolla, CA, USA., Halperin E; Department of Computer Science, University of California Los Angeles, Los Angeles, CA, USA.; Department of Human Genetics, University of California Los Angeles, Los Angeles, CA, USA.; Department of Anesthesiology and Perioperative Medicine, University of California Los Angeles, Los Angeles, CA, USA.; Department of Computational Medicine, University of California Los Angeles, Los Angeles, CA, USA.; Institute of Precision Health, University of California, Los Angeles, CA, USA., Knight R; Center for Microbiome Innovation, University of California San Diego, La Jolla, CA, USA. robknight@ucsd.edu.; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA. robknight@ucsd.edu.; Department of Computer Science and Engineering, University of California San Diego, La Jolla, CA, USA. robknight@ucsd.edu.; Department of Bioengineering, University of California San Diego, La Jolla, CA, USA. robknight@ucsd.edu.

Publikováno v: Nature biotechnology [Nat Biotechnol] 2021 Feb; Vol. 39 (2), pp. 165-168. Date of Electronic Publication: 2020 Aug 31.

Visualizing 'omic feature rankings and log-ratios using Qurro.

Autor: Fedarko MW; Department of Computer Science and Engineering, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.; Center for Microbiome Innovation, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA., Martino C; Center for Microbiome Innovation, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.; Bioinformatics and Systems Biology Program, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA., Morton JT; Flatiron Institute, Simons Foundation, 162 Fifth Avenue, New York City, NY 10010, USA., González A; Department of Pediatrics, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA., Rahman G; Bioinformatics and Systems Biology Program, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA., Marotz CA; Department of Biomedical Sciences, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA., Minich JJ; Marine Biology Research Division, Scripps Institution of Oceanography, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA., Allen EE; Center for Microbiome Innovation, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.; Marine Biology Research Division, Scripps Institution of Oceanography, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.; Department of Biological Sciences, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA., Knight R; Department of Computer Science and Engineering, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.; Center for Microbiome Innovation, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.; Department of Pediatrics, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.; Department of Bioengineering, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.

Publikováno v: NAR genomics and bioinformatics [NAR Genom Bioinform] 2020 Jun; Vol. 2 (2), pp. lqaa023. Date of Electronic Publication: 2020 Apr 28.

Antibiotic-induced microbiome depletion alters metabolic homeostasis by affecting gut signaling and colonic metabolism.

Autor: Zarrinpar A; Regulatory Biology Laboratory, The Salk Institute, 10010 N. Torrey Pines Road, La Jolla, CA, 92037, USA. azarrinp@ucsd.edu.; Division of Gastroenterology, University of California, San Diego, 9500 Gilman Drive, MC 0983, La Jolla, CA, 92093-0983, USA. azarrinp@ucsd.edu.; Center for Microbiome Innovation, University of California, San Diego, 9500 Gilman Drive, MC 0436, La Jolla, CA, 92093-0436, USA. azarrinp@ucsd.edu.; Division of Gastroenterology, VA San Diego Health Systems, 3350 La Jolla Village Drive, MC 9111D, La Jolla, CA, 92161, USA. azarrinp@ucsd.edu., Chaix A; Regulatory Biology Laboratory, The Salk Institute, 10010 N. Torrey Pines Road, La Jolla, CA, 92037, USA., Xu ZZ; Center for Microbiome Innovation, University of California, San Diego, 9500 Gilman Drive, MC 0436, La Jolla, CA, 92093-0436, USA.; Department of Pediatrics, University of California, San Diego, 9500 Gilman Drive, MC 0763, La Jolla, CA, 92093-0763, USA.; Department of Computer Science and Engineering, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA., Chang MW; Integrative Genomics and Bioinformatics Core, The Salk Institute, 10010 N. Torrey Pines Road, La Jolla, CA, 92037, USA.; Division of Endocrinology, University of California, San Diego, 9500 Gilman Drive #0640, La Jolla, CA, 92093-0640, USA., Marotz CA; Center for Microbiome Innovation, University of California, San Diego, 9500 Gilman Drive, MC 0436, La Jolla, CA, 92093-0436, USA.; Department of Pediatrics, University of California, San Diego, 9500 Gilman Drive, MC 0763, La Jolla, CA, 92093-0763, USA., Saghatelian A; Protein Biology Laboratory, The Salk Institute, 10010 N. Torrey Pines Road, La Jolla, CA, 92037, USA., Knight R; Center for Microbiome Innovation, University of California, San Diego, 9500 Gilman Drive, MC 0436, La Jolla, CA, 92093-0436, USA.; Department of Pediatrics, University of California, San Diego, 9500 Gilman Drive, MC 0763, La Jolla, CA, 92093-0763, USA.; Department of Computer Science and Engineering, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA., Panda S; Regulatory Biology Laboratory, The Salk Institute, 10010 N. Torrey Pines Road, La Jolla, CA, 92037, USA. panda@salk.edu.

Publikováno v: Nature communications [Nat Commun] 2018 Jul 20; Vol. 9 (1), pp. 2872. Date of Electronic Publication: 2018 Jul 20.