Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Maroof Husain"'
Autor:
Eugene Becker, Maroof Husain, Nathaniel Bone, Samuel Smith, Peter Morris, Jaroslaw W. Zmijewski
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-15 (2023)
Abstract Background Bacterial pneumonia and related lung injury are among the most frequent causes of mortality in intensive care units, but also inflict serious and prolonged respiratory complications among survivors. Given that endoplasmic reticulu
Externí odkaz:
https://doaj.org/article/976cecc335274dfc80152cedac53ca22
Autor:
Nathaniel B. Bone, Eugene J. Becker, Maroof Husain, Shaoning Jiang, Anna A. Zmijewska, Dae-Won Park, Balu Chacko, Victor Darley-Usmar, Murielle Grégoire, Jean-Marc Tadie, Victor J. Thannickal, Jaroslaw W. Zmijewski
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Metabolic and bioenergetic plasticity of immune cells is essential for optimal responses to bacterial infections. AMPK and Parkin ubiquitin ligase are known to regulate mitochondrial quality control mitophagy that prevents unwanted inflammat
Externí odkaz:
https://doaj.org/article/721d2c15ada041d197bf848bf5d4bb98
Autor:
Ahmed Zaky, Iram Zafar, Juan Xavier Masjoan-Juncos, Maroof Husain, Nithya Mariappan, Charity J. Morgan, Tariq Hamid, Michael A. Frölich, Shama Ahmad, Aftab Ahmad
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Background: Pulmonary arterial hypertension (PAH) is a progressive proliferative vasculopathy associated with mechanical and electrical changes, culminating in increased vascular resistance, right ventricular (RV) failure, and death. With a main focu
Externí odkaz:
https://doaj.org/article/86fab85a496c4bc9a171149045ee5a85
Autor:
Maroof Husain, Eugene J. Becker, Jr., Nathaniel B. Bone, Amy Schmitt, Jean-Francois Pittet, Jaroslaw W. Zmijewski
Publikováno v:
Redox Biology, Vol 36, Iss , Pp 101651- (2020)
Trauma and sepsis are frequent causes of immunosuppression and risk of secondary bacterial infections and mortality among critically ill patients. Reduced activity of neutrophil NADPH oxidase 2 (NOX2) and impaired bacterial killing are among the majo
Externí odkaz:
https://doaj.org/article/3fc45299a1494c6c8a454717fdf1b05a
Publikováno v:
Cell Reports, Vol 14, Iss 12, Pp 2901-2911 (2016)
The thiol-disulfide oxidoreductase CXXC catalytic domain of thioredoxin contributes to antioxidant defense in phylogenetically diverse organisms. We find that although the oxidoreductase activity of thioredoxin-1 protects Salmonella enterica serovar
Externí odkaz:
https://doaj.org/article/1dcff2f36c4e4faebb47cdc3e3cb5070
Publikováno v:
mBio, Vol 7, Iss 6 (2016)
ABSTRACT In the course of an infection, Salmonella enterica occupies diverse anatomical sites with various concentrations of oxygen (O2) and nitric oxide (NO). These diatomic gases compete for binding to catalytic metal groups of quinol oxidases. Ent
Externí odkaz:
https://doaj.org/article/c753637443f6408291a031610070c678
Background Bacterial pneumonia and related lung injury are among the most frequent causes of mortality in intensive care units, but also inflict serious and prolonged respiratory complications among survivors. Given that endoplasmic reticulum (ER) st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a3de71b4fcb72ba6c5a3c0ddf37ec15
https://doi.org/10.21203/rs.3.rs-2338974/v1
https://doi.org/10.21203/rs.3.rs-2338974/v1
Autor:
Tapasi Rana, Darshan S. Chandrashekar, Nithya Mariappan, Aftab Ahmad, Aamir Ahmad, Sooryanarayana Varambally, Tariq Hamid, Shama Ahmad, Iram Zafar, Maroof Husain
Publikováno v:
Ann N Y Acad Sci
Exposure of rats to 2-chloroethyl ethyl sulfide (CEES), an analog of sulfur mustard, can cause acute lung injury (ALI), resulting in increased inflammation and coagulation and altered levels of plasma microRNAs (miRNAs). Rats were exposed to aerosoli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab5310def0dc4c9f53277ae311852b09
https://doi.org/10.1111/nyas.14416
https://doi.org/10.1111/nyas.14416
Autor:
Maroof Husain, V. Singh, David R. Crowe, Kenneth G. Smithson, Nithya Mariappan, Aftab Ahmad, Shama Ahmad, Iram Zafar, Jean-Francois Pittet
Publikováno v:
Arch Toxicol
Sulfur mustard (SM) is a highly toxic war chemical that causes significant morbidity and mortality and lacks any effective therapy. Rats exposed to aerosolized CEES (2-chloroethyl ethyl sulfide; 10% in ethanol), an analog of SM, developed acute respi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ba9a43b854b3c643162503e1ab7c7b5
https://doi.org/10.1007/s00204-020-02699-1
https://doi.org/10.1007/s00204-020-02699-1
Autor:
Dae Won Park, Eugene J. Becker, Jean-Marc Tadié, Nathaniel B. Bone, Balu K. Chacko, Victor M. Darley-Usmar, Jaroslaw W. Zmijewski, Shaoning Jiang, Murielle Gregoire, Anna A. Zmijewska, Victor J. Thannickal, Maroof Husain
Publikováno v:
Scientific Reports
Scientific Reports, Nature Publishing Group, 2021, 11 (1), pp.12387. ⟨10.1038/s41598-021-90573-0⟩
Scientific Reports, 2021, 11 (1), pp.12387. ⟨10.1038/s41598-021-90573-0⟩
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports, Nature Publishing Group, 2021, 11 (1), pp.12387. ⟨10.1038/s41598-021-90573-0⟩
Scientific Reports, 2021, 11 (1), pp.12387. ⟨10.1038/s41598-021-90573-0⟩
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Metabolic and bioenergetic plasticity of immune cells is essential for optimal responses to bacterial infections. AMPK and Parkin ubiquitin ligase are known to regulate mitochondrial quality control mitophagy that prevents unwanted inflammatory respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02409ec88d5ab959deecc290264b2aa6
https://hal.archives-ouvertes.fr/hal-03260958/file/s41598-021-90573-0.pdf
https://hal.archives-ouvertes.fr/hal-03260958/file/s41598-021-90573-0.pdf