Immune regulation and blood–brain barrier permeability in cerebral small vessel disease: study protocol of the INflammation and Small Vessel Disease (INSVD) study – a multicentre prospective cohort study

Autor: Roy P C Kessels, Audrey Low, Hugh Markus, Anil Tuladhar, Frank‐Erik de Leeuw, Robin G Morris, Ziad Mallat, Niels P Riksen, Daniel J Tozer, Sanne van Winden, Lupei Cai, Marnix C Maas, Meritxell Nus, Anja van der Kolk, Rowan Wolters

Publikováno v: BMJ Open, Vol 14, Iss 2 (2024)

Introduction The INflammation and Small Vessel Disease (INSVD) study aims to investigate whether peripheral inflammation, immune (dys)regulation and blood–brain barrier (BBB) permeability relate to disease progression in cerebral small vessel disea

Externí odkaz: https://doaj.org/article/9de6a34a9f7443a3934e4e2d8c33f96d

Utility of T2-weighted MRI texture analysis in assessment of peripheral zone prostate cancer aggressiveness: a single-arm, multicenter study

Autor: Gabriel A. Nketiah, Mattijs Elschot, Tom W. Scheenen, Marnix C. Maas, Tone F. Bathen, Kirsten M. Selnæs, The PCa-MAP Consortium

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)

Abstract T2-weighted (T2W) MRI provides high spatial resolution and tissue-specific contrast, but it is predominantly used for qualitative evaluation of prostate anatomy and anomalies. This retrospective multicenter study evaluated the potential of T

Externí odkaz: https://doaj.org/article/1a7efed8f4d84711a0d8670e06081736

The Hyperintense study: Assessing the effects of induced blood pressure increase and decrease on MRI markers of cerebral small vessel disease: Study rationale and protocol

Autor: Esther Janssen, Annemieke ter Telgte, Esmée Verburgt, Joost JA de Jong, José P Marques, Roy PC Kessels, Walter H Backes, Marnix C Maas, Frederick JA Meijer, Jaap Deinum, Niels P Riksen, Anil M Tuladhar, Frank-Erik de Leeuw

Publikováno v: European Stroke Journal, 7(3):23969873221100331, 331-338. SAGE Publications Ltd
European Stroke Journal, 7, 331-338
European Stroke Journal, 7, 3, pp. 331-338

Background: Neuroimaging markers of cerebral small vessel disease (SVD) are common in older individuals, but the pathophysiological mechanisms causing these lesions remain poorly understood. Although hypertension is a major risk factor for SVD, the d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31584cc9a07349279aa86ac8e3e56788
https://doi.org/10.1177/23969873221100331

The radiological interpretation of possible microbleeds after moderate or severe traumatic brain injury: a longitudinal study

Autor: Anke W. van der Eerden, Pieter E. Vos, Bozena Goraj, Thomas L. A. van den Heuvel, Priya Vart, Rashindra Manniesing, Marnix C. Maas, Bram Platel

Publikováno v: Neuroradiology, 64(6). Springer-Verlag
Neuroradiology, 64, 1145-1156
Neuroradiology, 64, 6, pp. 1145-1156

Introduction In order to augment the certainty of the radiological interpretation of “possible microbleeds” after traumatic brain injury (TBI), we assessed their longitudinal evolution on 3-T SWI in patients with moderate/severe TBI. Methods Stan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::806761937bdbeefdcfeb323a7c08ceee
https://pubmed.ncbi.nlm.nih.gov/34719725

Post-exercise intramuscular O

Autor: Linda, Heskamp, Franciska, Lebbink, Mark J, van Uden, Marnix C, Maas, Jurgen A H R, Claassen, Martijn, Froeling, Graham J, Kemp, Andreas, Boss, Arend, Heerschap

Publikováno v: The Journal of Physiology

Key points The post‐exercise recovery of phosphocreatine, a measure of the oxidative capacity of muscles, as assessed by 31P MR spectroscopy, shows a striking increase from distal to proximal along the human tibialis anterior muscle.To investigate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::32a1520787342ef97e8ea2837bb84a08
https://pubmed.ncbi.nlm.nih.gov/33369737