Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Marnix, Van Loock"'
Autor:
Dominik Kiemel, Ann-Sophie Helene Kroell, Solène Denolly, Uta Haselmann, Jean-François Bonfanti, Jose Ignacio Andres, Brahma Ghosh, Peggy Geluykens, Suzanne J. F. Kaptein, Lucas Wilken, Pietro Scaturro, Johan Neyts, Marnix Van Loock, Olivia Goethals, Ralf Bartenschlager
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Dengue fever represents a significant medical and socio-economic burden in (sub)tropical regions, yet antivirals for treatment or prophylaxis are lacking. JNJ-A07 was described as highly active against the different genotypes within each ser
Externí odkaz:
https://doaj.org/article/e78ff1b130a7428d836ca61a6614a777
Autor:
Yalda Jafari, Oliver J Brady, Joseph R Biggs, Le Thuy Lien, Huynh Kim Mai, Hien Anh Thi Nguyen, Marnix Van Loock, Guillermo Herrera-Taracena, Joris Menten, Chihiro Iwasaki, Mizuki Takegata, Noriko Kitamura, Hung Do Thai, Bui Xuan Minh, Kouichi Morita, Dang Duc Anh, Sam Clifford, Kiesha Prem, Julius Hafalla, W John Edmunds, Lay Myint Yoshida, Martin L Hibberd, Stéphane Hué
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 7, p e0012334 (2024)
Prophylactic drugs against dengue are currently under development. In this study, we explored how such prophylactic approaches might affect dengue cases in four communes of Nha Trang City, Vietnam. A community level dengue transmission survey indicat
Externí odkaz:
https://doaj.org/article/a985c8656fbf403a9cc7dd6d70d3e6a7
Autor:
Jordi Doijen, Koen Temmerman, Christel Van den Eynde, Annick Diels, Nick Van den Broeck, Michiel Van Gool, Inha Heo, Steffen Jaensch, Marleen Zwaagstra, Mayra Diosa Toro, Winston Chiu, Steven De Jonghe, Pieter Leyssen, Denisa Bojkova, Sandra Ciesek, Jindrich Cinatl, Lore Verschueren, Christophe Buyck, Frank Van Kuppeveld, Johan Neyts, Marnix Van Loock, Ellen Van Damme
Publikováno v:
Microorganisms, Vol 11, Iss 3, p 717 (2023)
The ongoing COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is partly under control by vaccination. However, highly potent and safe antiviral drugs for SARS-CoV-2 are still needed to avoid development of sev
Externí odkaz:
https://doaj.org/article/c44476726dbf4c47a12d38fe05172f8d
Autor:
Joseph R Biggs, Ava Kristy Sy, James Ashall, Marsha S Santoso, Oliver J Brady, Mary Anne Joy Reyes, Mary Ann Quinones, William Jones-Warner, Amadou O Tandoc, Nemia L Sucaldito, Huynh Kim Mai, Le Thuy Lien, Hung Do Thai, Hien Anh Thi Nguyen, Dang Duc Anh, Chihiro Iwasaki, Noriko Kitamura, Marnix Van Loock, Guillermo Herrera-Taracena, Joris Menten, Freya Rasschaert, Liesbeth Van Wesenbeeck, Sri Masyeni, Sotianingsih Haryanto, Benediktus Yohan, Eva Cutiongco-de la Paz, Lay-Myint Yoshida, Stephane Hue, Maria Rosario Z Capeding, Carmencita D Padilla, R Tedjo Sasmono, Julius Clemence R Hafalla, Martin L Hibberd
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 16, Iss 5, p e0010365 (2022)
BackgroundCharacterising dengue virus (DENV) infection history at the point of care is challenging as it relies on intensive laboratory techniques. We investigated how combining different rapid diagnostic tests (RDTs) can be used to accurately determ
Externí odkaz:
https://doaj.org/article/f7c9d62d3c114b468c7901822b660b94
Autor:
Sandra De Meyer, Denisa Bojkova, Jindrich Cinatl, Ellen Van Damme, Christophe Buyck, Marnix Van Loock, Brian Woodfall, Sandra Ciesek
Publikováno v:
International Journal of Infectious Diseases, Vol 97, Iss , Pp 7-10 (2020)
Objectives: Given the high need and the absence of specific antivirals for treatment of COVID-19 (the disease caused by severe acute respiratory syndrome-associated coronavirus-2 [SARS-CoV-2]), human immunodeficiency virus (HIV) protease inhibitors a
Externí odkaz:
https://doaj.org/article/90d3b12b6ba74d96bc31c99b569501e3
Autor:
Oliver J. Brady, Adam J. Kucharski, Sebastian Funk, Yalda Jafari, Marnix Van Loock, Guillermo Herrera-Taracena, Joris Menten, W. John Edmunds, Shuzhen Sim, Lee-Ching Ng, Stéphane Hué, Martin L. Hibberd
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 8 (2021)
Background Targeting interventions to areas that have recently experienced cases of disease is one strategy to contain outbreaks of infectious disease. Such case-area targeted interventions (CATI) have become an increasingly popular approach for deng
Externí odkaz:
https://doaj.org/article/070259434f324848a82840c40e1d1de1
Autor:
Olivia Goethals, Suzanne J. F. Kaptein, Bart Kesteleyn, Jean-François Bonfanti, Liesbeth Van Wesenbeeck, Dorothée Bardiot, Ernst J. Verschoor, Babs E. Verstrepen, Zahra Fagrouch, J. Robert Putnak, Dominik Kiemel, Oliver Ackaert, Roel Straetemans, Sophie Lachau-Durand, Peggy Geluykens, Marjolein Crabbe, Kim Thys, Bart Stoops, Oliver Lenz, Lotke Tambuyzer, Sandra De Meyer, Kai Dallmeier, Michael K. McCracken, Gregory D. Gromowski, Wiriya Rutvisuttinunt, Richard G. Jarman, Nicos Karasavvas, Franck Touret, Gilles Querat, Xavier de Lamballerie, Laurent Chatel-Chaix, Gregg N. Milligan, David W. C. Beasley, Nigel Bourne, Alan D. T. Barrett, Arnaud Marchand, Tim H. M. Jonckers, Pierre Raboisson, Kenny Simmen, Patrick Chaltin, Ralf Bartenschlager, Willy M. Bogers, Johan Neyts, Marnix Van Loock
Publikováno v:
Nature. 615:678-686
Dengue is a major health threat and the number of symptomatic infections caused by the four dengue serotypes is estimated to be 96 million1 with annually around 10,000 deaths2. However, no antiviral drugs are available for the treatment or prophylaxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f8c0a4183f19bf33ac0d110d21b457f
https://doi.org/10.1038/s41586-023-05790-6
https://doi.org/10.1038/s41586-023-05790-6
Autor:
Sandrine Grosse, Abdellah Tahri, Pierre Raboisson, Yannis Houpis, Bart Stoops, Edgar Jacoby, Jean-Marc Neefs, Marnix Van Loock, Olivia Goethals, Peggy Geluykens, Jean-François Bonfanti, Tim H. M. Jonckers
Publikováno v:
ACS Medicinal Chemistry Letters. 13:1879-1884
In continuation of our efforts of finding novel nucleoside inhibitors for the treatment of viral diseases, we initiated a discovery research program aimed at identifying novel nucleos(t)ide inhibitors for emerging diseases like Dengue and Chikungunya
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62a6a84c256df58b86b9b102ba666666
https://doi.org/10.1021/acsmedchemlett.2c00372
https://doi.org/10.1021/acsmedchemlett.2c00372
Autor:
Winston Chiu, Lore Verschueren, Christel Van den Eynde, Christophe Buyck, Sandra De Meyer, Dirk Jochmans, Denisa Bojkova, Sandra Ciesek, Jindrich Cinatl, Steven De Jonghe, Pieter Leyssen, Johan Neyts, Marnix Van Loock, Ellen Van Damme
Publikováno v:
Journal of Medical Virology
Although vaccines are currently used to control the coronavirus disease 2019 (COVID-19) pandemic, treatment options are urgently needed for those who cannot be vaccinated and for future outbreaks involving new severe acute respiratory syndrome corona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bca807f5069687836a15ea6b94c58db3
https://doi.org/10.1002/jmv.27683
https://doi.org/10.1002/jmv.27683
A phylogenetic study of dengue virus in urban Vietnam shows long-term persistence of endemic strains
Autor:
James Ashall, Sonal Shah, Joseph R Biggs, Jui-Ning R Chang, Yalda Jafari, Oliver J Brady, Huynh Kim Mai, Le Thuy Lien, Hung Do Thai, Hien Anh Thi Nguyen, Dang Duc Anh, Chihiro Iwasaki, Noriko Kitamura, Marnix Van Loock, Guillermo Herrera-Taracena, Freya Rasschaert, Liesbeth Van Wesenbeeck, Lay-Myint Yoshida, Julius Clemence R Hafalla, Stephane Hue, Martin L Hibberd
Publikováno v:
Virus Evolution. 9
Dengue virus (DENV) causes repeated outbreaks of disease in endemic areas, with patterns of local transmission strongly influenced by seasonality, importation via human movement, immunity, and vector control efforts. An understanding of how each of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b4b4442d7d8abad755d1836c6740a27
https://doi.org/10.1093/ve/vead012
https://doi.org/10.1093/ve/vead012