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pro vyhledávání: '"Marnie A. Phillips"'
Early-life blindness causes lasting visual impairment, for which the circuit basis is only partially understood. Degradation of visual connections as well as the network dynamics supporting neural oscillations and arousal states are likely contributo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd188b826fcca18e748907471120f35d
https://doi.org/10.1101/2022.11.11.516158
https://doi.org/10.1101/2022.11.11.516158
Publikováno v:
Neuron. 109:3400-3401
In this issue of Neuron, Ibrahim et al. (2021) examine the rules by which top-down connections are made on visual cortical layer 1 interneurons, discovering activity-dependent cooperative interactions with visual input that are specific to neurogliaf
Publikováno v:
eNeuro
The isocortex of all mammals studied to date shows a progressive increase in the amount and continuity of background activity during early development. In humans the transition from a discontinuous (mostly silent, intermittently bursting) cortex to o
Publikováno v:
Current opinion in neurobiology. 52
Thalamocortical activity patterns, both spontaneous and evoked, undergo a dramatic shift in preparation for the onset of rich sensory experience (e.g. birth in humans; eye-opening in rodents). This change is the result of a switch from thalamocortica
Publikováno v:
Scientific Reports
Fragile X syndrome (FXS) is characterized by sensory hyper-sensitivity, and animal models suggest that neuronal hyper-excitability contributes to this phenotype. To understand how sensory dysfunction develops in FXS, we used the rat model (FMR-KO) to
Publikováno v:
Scientific Reports.
Fragile X syndrome (FXS) is characterized by sensory hyper-sensitivity, and animal models suggest that neuronal hyper-excitability contributes to this phenotype. To understand how sensory dysfunction develops in FXS, we used the rat model (FMR-KO) to
Autor:
Julie Goldberg, Matthew T. Colonnese, Laura D. Lewis, Emery N. Brown, Marnie A. Phillips, Martha Constantine-Paton
Publikováno v:
Neuron. 71:710-724
The mechanisms by which experience guides refinement of converging afferent pathways are poorly understood. We describe a vision-driven refinement of cortico-collicular inputs that determines the consolidation of retinal and visual cortical (VC) syna
Publikováno v:
The Journal of Neuroscience. 26:12647-12655
The visual layers of the rodent superficial superior colliculus (sSC) have been the focus of many development studies of the molecular bases of retinotopic map formation, the role of early retinal waves in this process, and the development of glutama
N-methyl-d-aspartate receptors (NMDARs) have been linked to schizophrenia because agents that bind the receptor, like ketamine and phencyclidine, are capable of inducing schizophrenia-like symptoms. Here we show that the amino acid homocysteine (HCY)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d86b5e6cc1dc270fcc1a27e96e81211
https://europepmc.org/articles/PMC4042420/
https://europepmc.org/articles/PMC4042420/
Autor:
Jing Shen, Chongxi Lai, Julia Berzhanskaya, Marnie A. Phillips, Alexis Gorin, Matthew T. Colonnese
Publikováno v:
Cerebral Cortex. :bhv331
Children with Fragile X syndrome (FXS) have deficits of attention and arousal. To begin to identify the neural causes of these deficits, we examined juvenile rats lacking the Fragile X mental retardation protein (FMR-KO) for disruption of cortical ac