Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Marni A. Nenke"'
Autor:
Emily Jane Meyer, Marni Anne Nenke, Michael Laurence Davies, Marianne Chapman, Wayne Rankin, R Louise Rushworth, David James Torpy
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 107:1636-1646
Context Hydrocortisone administration in septic shock remains controversial. Corticosteroid-binding globulin (CBG) transports cortisol to inflammatory sites and is depleted in septic shock. Objective To determine whether severely deficient serum CBG
Publikováno v:
Liver International. 43:740-741
Autor:
Sayantani, Chatterjee, Rebeca, Kawahara, Harry C, Tjondro, David R, Shaw, Marni A, Nenke, David J, Torpy, Morten, Thaysen-Andersen
Publikováno v:
Journal of Clinical Medicine
Bacteremia—i.e., the presence of pathogens in the blood stream—is associated with long-term morbidity and is a potential precursor condition to life-threatening sepsis. Timely detection of bacteremia is therefore critical to reduce patient mortal
Autor:
Morten Thaysen-Andersen, John G. Lewis, Harinda Rajapaksha, Steven W. Polyak, Marni A. Nenke, Wayne Rankin, Anastasia Chernykh, Emily J. Meyer, David J. Torpy
Publikováno v:
Protein Sci
Corticosteroid‐binding globulin (CBG) transports cortisol and other steroids. High‐affinity CBG (haCBG) undergoes proteolysis of the reactive center loop (RCL) by neutrophil elastase (NE) altering conformation to low‐affinity CBG (laCBG). Eleva
Autor:
Steven W. Polyak, Marni A. Nenke, Morten Thaysen-Anderson, Emily J Meyer, John G. Lewis, Wayne Rankin, Anastasia Chernykh, David J. Torpy
Publikováno v:
Journal of the Endocrine Society
Context Corticosteroid-binding globulin (CBG) transports cortisol and other steroid hormones1,2. High-affinity CBG (haCBG) undergoes proteolysis of the reactive centre loop (RCL) by neutrophil elastase (NE) at inflammatory sites, liberating immunomod
Autor:
Elisabeth E.M. Konings, David J. Torpy, Marni A. Nenke, Emily J. Meyer, Tim C. Jansen, Maarten A. Slager, Jan Bakker, John G. Lewis, Richard A Feelders, Johannes Hofland, Wayne Rankin
Publikováno v:
Clinical Endocrinology, 90(1), 232-240. Wiley-Blackwell Publishing Ltd
Corticosteroid-binding globulin (CBG) and albumin transport circulating cortisol. Cleavage of high-affinity CBG (haCBG) by neutrophil elastase at inflammatory sites causes cortisol release into tissues, facilitating immunomodulatory effects.To determ
Autor:
Emily J. Meyer, Michael Stark, Nicolette A. Hodyl, John G. Lewis, Marni A. Nenke, David J. Torpy
Publikováno v:
European journal of obstetrics, gynecology, and reproductive biology. 251
Objective Corticosteroid-binding globulin (CBG) binds and transports cortisol in the circulation in high cortisol-binding affinity (haCBG) and low affinity (laCBG) forms, the latter resulting from enzyme cleavage to target cortisol delivery at sites
Autor:
Sayantani Chatterjee, David R. Shaw, David J. Torpy, Marni A. Nenke, Harry C. Tjondro, Morten Thaysen-Andersen, Rebeca Kawahara
Publikováno v:
Journal of Clinical Medicine, Vol 10, Iss 516, p 516 (2021)
Journal of Clinical Medicine
Volume 10
Issue 3
Journal of Clinical Medicine
Volume 10
Issue 3
Bacteremia—i.e., the presence of pathogens in the blood stream—is associated with long-term morbidity and is a potential precursor condition to life-threatening sepsis. Timely detection of bacteremia is therefore critical to reduce patient mortal
Publikováno v:
Hormone and Metabolic Research. 48:523-528
Corticosteroid-binding globulin (CBG) is involved in the regulation of cortisol delivery. Neutrophil elastase-mediated cleavage of high to low affinity CBG (haCBG to laCBG) induces cortisol release at inflammatory sites. Past studies have shown reduc
Publikováno v:
Hormone and Metabolic Research. 48:359-371
Corticosteroid-binding globulin (CBG, transcortin) is the primary cortisol binding protein. It is a non-inhibitory serine protease inhibitor, capable of conformational change from a high cortisol-binding affinity form to a low affinity form upon clea