Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Marmar Moussa"'
Autor:
Hakimeh Ebrahimi-Nik, Marmar Moussa, Ryan P. Englander, Summit Singhaviranon, Justine Michaux, HuiSong Pak, Hiroko Miyadera, William L. Corwin, Grant L. J. Keller, Adam T. Hagymasi, Tatiana V. Shcheglova, George Coukos, Brian M. Baker, Ion I. Mandoiu, Michal Bassani-Sternberg, Pramod K. Srivastava
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
The immunogenicity of peptides is believed to be determined by their high-affinity binding to MHC I. Here authors show that low-affinity MHC I-peptide interactions are also able to trigger robust T cell response and anti-tumour immunity in vivo.
Externí odkaz:
https://doaj.org/article/1e4f015d0d0f4721934a300013d3a61f
Autor:
Marmar Moussa, Ion I. Măndoiu
Publikováno v:
BMC Genomics, Vol 19, Iss S6, Pp 31-45 (2018)
Abstract Background Single cell transcriptomics is critical for understanding cellular heterogeneity and identification of novel cell types. Leveraging the recent advances in single cell RNA sequencing (scRNA-Seq) technology requires novel unsupervis
Externí odkaz:
https://doaj.org/article/b2d2322f7e164efc88bd7ef458c1fa23
Autor:
Mukul S. Bansal, Ion I. Măndoiu, Marmar Moussa, Murray Patterson, Sanguthevar Rajasekaran, Pavel Skums, Alexander Zelikovsky
Publikováno v:
Journal of Computational Biology. 30:363-365
Autor:
William L. Corwin, Ryan P. Englander, Hakimeh Ebrahimi-Nik, Michal Bassani-Sternberg, Pramod K. Srivastava, Grant L.J. Keller, Adam T. Hagymasi, Marmar Moussa, Brian M. Baker, Tatiana Shcheglova, Ion I. Mandoiu, George Coukos, Hiroko Miyadera, Summit Singhaviranon, HuiSong Pak, Justine Michaux
Publikováno v:
Nature communications, vol. 12, no. 1, pp. 6423
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Nature Communications
High-affinity MHC I-peptide interactions are considered essential for immunogenicity. However, some neo-epitopes with low affinity for MHC I have been reported to elicit CD8 T cell dependent tumor rejection in immunization-challenge studies. Here we
Autor:
Owen White, Kimberly A. Smith, Brian D. Aevermann, William J. Romanow, Joseph R. Ecker, Michael Tieu, Michael Hawrylycz, Sheng-Yong Niu, Brian R. Herb, Jacinta Lucero, Sten Linnarsson, Tanya L. Daigle, Christine S. Liu, Ed S. Lein, Boudewijn P. F. Lelieveldt, Zizhen Yao, Yang Eric Li, Stephan Fischer, Trygve E. Bakken, Jeremy A. Miller, C. Dirk Keene, Scott F. Owen, Wei Tian, Joshua Orvis, Nongluk Plongthongkum, Rosa Castanon, Megan Crow, Thomas Höllt, Bing Ren, Darren Bertagnolli, Weixiu Dong, Herman Tung, Baldur van Lew, Delissa McMillen, Bosiljka Tasic, Angeline Rivkin, Eran A. Mukamel, Nora Reed, Alexander Dobin, Chongyuan Luo, Patrick R. Hof, Nick Dee, Rongxin Fang, Kirsten Crichton, M. Margarita Behrens, Anna Bartlett, Renee Zhang, Olivier Poirion, Josef Sulc, Philip R. Nicovich, Rebecca D. Hodge, Evan Z. Macosko, Staci A. Sorensen, Dinh Diep, Thanh Pham, Songlin Ding, Richard H. Scheuermann, Jayaram Kancherla, Jeroen Eggermont, Seth A. Ament, Ronna Hertzano, Jeff Goldy, Christine Rimorin, Julia K. Osteen, Kimberly Siletti, Steven A. McCarroll, Hanqing Liu, C. Palmer, Saroja Somasundaram, Jonathan T. Ting, Jerold Chun, Xiaomeng Hou, Guoping Feng, Kun Zhang, Fenna M. Krienen, Blue B. Lake, Amy Torkelson, Hongkui Zeng, Sebastian Preissl, Christof Koch, Nikolas L. Jorstad, Andrew L. Ko, Héctor Corrada Bravo, Aviv Regev, Nikolai C. Dembrow, Kanan Lathia, Antonio Pinto-Duarte, Xinxin Wang, Lucas T. Graybuck, Melissa Goldman, Marmar Moussa, William J. Spain, Peter V. Kharchenko, Qiwen Hu, Adriana E. Sedeno-Cortes, Gregory D. Horwitz, Rachel A. Dalley, Anup Mahurkar, Brian E. Kalmbach, Andrew Aldridge, Jesse Gillis, Anna Marie Yanny, Joseph R. Nery, Tamara Casper, Fangming Xie, Matthew Kroll
Publikováno v:
Nature, 598(7879), 111-119. NATURE PORTFOLIO
Nature
Nature: international weekly journal of science, 598(7879)
Nature
Nature: international weekly journal of science, 598(7879)
The primary motor cortex (M1) is essential for voluntary fine-motor control and is functionally conserved across mammals1. Here, using high-throughput transcriptomic and epigenomic profiling of more than 450,000 single nuclei in humans, marmoset monk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec172c4ec74873eefac841febd1a5574
https://www.nature.com/articles/s41586-021-03465-8.pdf
https://www.nature.com/articles/s41586-021-03465-8.pdf
Autor:
Ion I. Mandoiu, Marmar Moussa
Publikováno v:
Journal of computational biology : a journal of computational molecular cell biology. 28(8)
Single cell RNA-seq (scRNA-Seq) is critical for studying cellular function and phenotypic heterogeneity as well as the development of tissues and tumors. Here, we present a web-based interactive scRNA-Seq data analysis tool publicly accessible at htt
Publikováno v:
The Journal of Immunology. 208:119.07-119.07
The neuroimmune response to stress has been linked to enhanced tumor proliferation, angiogenesis, and metastasis. In particular, signaling through β-adrenergic receptors has been demonstrated to promote a highly immunosuppressive tumor microenvironm
Publikováno v:
The Journal of Immunology. 208:169.10-169.10
The sympathetic nervous system (SNS) innervates all lymphoid tissues and is, thus, well-positioned to influence the activity of immune cells. Accordingly, the coordinated responses of the SNS and immune system are crucial for immune responses to infe
Autor:
Marmar Moussa, Ion I. Mandoiu
Single cell RNA-Seq (scRNA-Seq) is critical for studying cellular function and phenotypic heterogeneity as well as the development of tissues and tumors. Here, we present SC1 a web-based highly interactive scRNA-Seq data analysis tool publicly access
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e20f04789179fbb18fb01557d211d57
https://doi.org/10.1101/2021.03.19.435534
https://doi.org/10.1101/2021.03.19.435534
Autor:
Tatiana Shcheglova, Ion I. Mandoiu, Mariam M. George, Sahar Al Seesi, Cory A. Brennick, Jeremy L. Balsbaugh, Ryan P. Englander, Grant L.J. Keller, Andrea Schietinger, Pramod K. Srivastava, Adam T. Hagymasi, Marmar Moussa, Brian M. Baker
Publikováno v:
The Journal of Clinical Investigation
Identification of neoepitopes that are effective in cancer therapy is a major challenge in creating cancer vaccines. Here, using an entirely unbiased approach, we queried all possible neoepitopes in a mouse cancer model and asked which of those are e