Výsledky vyhledávání - "Marlys H. Gee"

Neutrophil recruitment as a factor limiting injury or promoting recovery from acute lung injury

Autor: S. Z. Perkowski, Marlys H. Gee, J. A. Spath, C. L. Lipsky, Lisa A. Carey, R. A. Cirelli

Publikováno v: American Journal of Physiology-Heart and Circulatory Physiology. 272:H279-H289

We studied 1) neutrophil mobilization in sheep given endotoxin (10 ng.kg-1.min-1, n = 5) for 4 h, 2) surviving (n = 17) and nonsurviving sheep (n = 8) during a 12-h infusion of endotoxin, and 3) adult sheep (n = 8) or lambs (n = 8) infused with endot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0fb7fdab203698228a9ecf44d33097c
https://doi.org/10.1152/ajpheart.1997.272.1.h279

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AN ASSOCIATION BETWEEN LUNG LYMPH ENDOTHELIN CONCENTRATION AND SURVIVAL DURING ENDOTOXEMIA IN AWAKE SHEEP

Autor: Sandra Z. Perkowski, Marlys H. Gee, Valerie E. Armstead, Marilyn J. Woolkalis, J. A. Spath

Publikováno v: Shock. 4:361-367

Endotoxin stimulates synthesis of endothelin which can cause pulmonary and systemic vasoconstriction and bronchoconstriction. Prolonged endotoxemia in sheep results in dramatic increases in pulmonary and systemic vascular resistances in nonsurvivors

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50b4bf809481d6a9668d7f38cb87803a
https://doi.org/10.1097/00024382-199511000-00009

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Loss of endothelium-dependent vasodilation in the pulmonary vessels of sheep after prolonged endotoxin

Autor: P. J. Sloane, Kurt H. Albertine, J. A. Spath, Marlys H. Gee

Publikováno v: Journal of Applied Physiology. 76:361-369

We examined the hemodynamic response of awake sheep to prolonged endotoxin infusion (10 ng.kg-1 x min-1 for 12 h) and the in vitro endothelium-dependent relaxation of pulmonary arterial vessels excised 12 h after the end of endotoxin infusion to dete

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c30f59f8ac2a4d9b7b26a55d93e5e82
https://doi.org/10.1152/jappl.1994.76.1.361

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Neutrophil-Endothelial Cell Interactions in the Lung

Autor: Marlys H. Gee, Kurt H. Albertine

Publikováno v: Annual Review of Physiology. 55:227-248

The large marginated pool of neutrophils normally present in the pulmonary circulation provides a unique opportunity to study the relationship between neutrophils and endothelial cells in situ. Unlike other organs in which neutrophil density in the v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e05bc66e28af98df02d6b2e0ab14cbe
https://doi.org/10.1146/annurev.ph.55.030193.001303

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Downregulation of blood and bone marrow neutrophils decreases expression of acute lung injury in sheep

Autor: P J McKenna, Marlys H. Gee, Yoko Ishihara, D. L. Rosolia, Norman C. Staub, Kurt H. Albertine

Publikováno v: American Journal of Physiology-Heart and Circulatory Physiology. 263:H1492-H1498

We have shown that infusion of zymosan-activated plasma (ZAP) in sheep causes acute lung injury and downregulates peripheral blood neutrophils in that elicited superoxide release is reduced for at least 24 h after the infusion. The present study was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::510b66935de83c0f16ae9edf34cb22b2
https://doi.org/10.1152/ajpheart.1992.263.5.h1492

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Physiology of aging related to outcome in the adult respiratory distress syndrome

Autor: Stephen P. Peters, Marlys H. Gee, James E. Fish, J. M. Kubis, Jonathan E. Gottlieb, Kurt H. Albertine

Publikováno v: Journal of Applied Physiology. 69:822-829

Thirty-nine patients with adult respiratory distress syndrome (ARDS) were enrolled in a study to identify potential age-related changes in organ system function that may help explain the apparent association between age and poor outcome in these pati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d90646151fac1997c23a7d52da0e1f99
https://doi.org/10.1152/jappl.1990.69.3.822

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Calcium Is Required for PMA Induced Superoxide Release From Human Neutrophils

Autor: Kurt H. Albertine, Marlys H. Gee, P J McKenna, D. L. Rosolia, Stephen P. Peters, Yoko Ishihara

Publikováno v: Journal of Leukocyte Biology. 48:89-96

Experiments were designed to reexamine the relationship between extracellular calcium and superoxide generation in phorbol myristate acetate (PMA) stimulated neutrophils exploiting a newly adapted method to measure superoxide anion (O2-) generation f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5cfc0ae52b0e207d7210ccc260aeab9
https://doi.org/10.1002/jlb.48.1.89

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Superoxide anion release from blood and bone marrow neutrophils is altered by endotoxemia

Autor: Marlys H. Gee, Kurt H. Albertine, Stephen P. Peters, D. L. Rosolia, P J McKenna, Franklin Cerasoli

Publikováno v: Circulation Research. 67:154-165

In vivo endotoxin infusion produces neutrophil-mediated acute lung injury and increases superoxide anion release from phorbol myristate acetate (PMA)-stimulated blood neutrophils collected 18-24 hours after the infusion. Because the turnover time of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e052e9a69b90a5782223b103c2fccf65
https://doi.org/10.1161/01.res.67.1.154

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