Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Marlyne Goulet"'
Publikováno v:
Cell Transplantation, Vol 23 (2014)
The aim of this study was to quantitatively define the main measurable technical parameters for the intramuscular transplantation of myogenic cells in primates. Myoblasts transduced with the gene coding for β-galactosidase were injected into the ske
Externí odkaz:
https://doaj.org/article/690f88701fc64e94b253a24b29d98fe7
Autor:
Pierre-Luc Richard, Clément Gosselin, Thierry Laliberté, Martin Paradis, Marlyne Goulet, Jacques P. Tremblay, Daniel Skuk M.D.
Publikováno v:
Cell Transplantation, Vol 19 (2010)
Intramuscular cell transplantation in humans requires so far meticulous repetitive cell injections. Performed percutaneously with syringes operated manually, the procedure is very time consuming and requires a lot of concentration to deliver the cell
Externí odkaz:
https://doaj.org/article/13be4559be2245089b75479be380ea88
Autor:
Jean-François Lafreniere, Marie-Christine Caron, Daniel Skuk, Marlyne Goulet, Anissa Rahma Cheikh, Jacques P. Tremblay
Publikováno v:
Cell Transplantation, Vol 18 (2009)
Duchenne muscular dystrophy (DMD) is an inherited disease and a main target of myogenic cell transplantation (MT). After the failure of the first clinical trials with DMD patients, the poor migration of transplanted cells has been suspected to be a m
Externí odkaz:
https://doaj.org/article/a33f0857bea04f69a247b265318c1d10
Publikováno v:
Cell Transplantation, Vol 15 (2006)
Intramuscular myoblast transplantation in humans and nonhuman primates requires precise repetitive cell injections very close to each other. Performed with syringes operated manually throughout large regions, this procedure takes a lot of time, becom
Externí odkaz:
https://doaj.org/article/800215e24a20495c98362c77e2624db6
Autor:
Daniel Skuk, Nicolas Caron, Marlyne Goulet, Brigitte Roy, Francisco Espinosa, Jacques P. Tremblay Ph.D.
Publikováno v:
Cell Transplantation, Vol 11 (2002)
The role of immune cells in the early donor cell death/survival following myoblast transplantation is confusing, one of the reasons being the lack of data about the immune reactions following cell transplantation. We used outbred mice as hosts for tr
Externí odkaz:
https://doaj.org/article/582882a8d93c45db8a7bae8ad03be843
Publikováno v:
Cell Transplantation, Vol 23 (2014)
The aim of this study was to quantitatively define the main measurable technical parameters for the intramuscular transplantation of myogenic cells in primates. Myoblasts transduced with the gene coding for β-galactosidase were injected into the ske
Publikováno v:
Neuromuscular Disorders. 23:155-159
A rhesus macaque with generalized muscle atrophy and musculotendinous contractures was detected in our research center. Muscle biopsies showed myofibers with rimmed vacuoles and eosinophilic hyaline inclusions, accumulations of CD8+ and CD4+ lymphocy
Publikováno v:
Transplantation. 84:1307-1315
BACKGROUND Several cell-transplantation strategies implicate the injection of cells into tissues. Avascular accumulations of implanted cells are then formed. Because the diffusion of oxygen and nutrients from the surrounding tissue throughout the imp
Autor:
Brigitte Roy, K Leriche-Guérin, Jacques P. Tremblay, Marlyne Goulet, L.V.B. Anderson, Klaus Wrogemann
Publikováno v:
Neuromuscular Disorders. 12:167-173
Limb girdle muscular dystrophy type 2B form and Miyoshi myopathy are both caused by mutations in the recently cloned gene dysferlin. In the present study, we have investigated whether cell transplantation could permit dysferlin expression in vivo. Tw
Publikováno v:
Journal of Neuropathology & Experimental Neurology. 59:197-206
The goal of the present study was to determine the feasibility, success, and toxicity of myoblast transplantation (MT) in the whole muscle of primates. Allogenic myoblasts transduced with the beta-galactosidase (beta-Gal) gene were transplanted in th