Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Marloes van Roijen"'
Publikováno v:
Molecular Brain, Vol 16, Iss 1, Pp 1-5 (2023)
Abstract Synaptic degeneration is a precursor of synaptic and neuronal loss in neurodegenerative diseases such as Alzheimer’s disease (AD) and frontotemporal dementia with tau pathology (FTD-tau), a group of primary tauopathies. A critical role in
Externí odkaz:
https://doaj.org/article/373093bdf15547e2980ab7ec67eb4114
Autor:
Juan Carlos Polanco, Yevhen Akimov, Avinash Fernandes, Gabriel Rhys Hand, Adam Briner, Marloes van Roijen, Giuseppe Balistreri, Jürgen Götz
Aggregation of the microtubule-associated protein tau is a defining feature of Alzheimer’s disease and other tauopathies. Tau pathology is believed to be driven by both free tau aggregates and tau carried within exosomes, which propagate trans-syna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a02331d9d6e2d7129094257cedff3965
https://doi.org/10.1101/2022.04.26.489622
https://doi.org/10.1101/2022.04.26.489622
Autor:
Juan Carlos Polanco, Yevhen Akimov, Avinash Fernandes, Adam Briner, Gabriel Rhys Hand, Marloes van Roijen, Giuseppe Balistreri, Jürgen Götz
Publikováno v:
Life Science Alliance. 6:e202201689
The aggregation of the microtubule-associated protein tau is a defining feature of Alzheimer’s disease and other tauopathies. Tau pathology is believed to be driven by free tau aggregates and tau carried within exosome-like extracellular vesicles,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70f04559de61236230bb08bc45783927
https://doi.org/10.26508/lsa.202201689
https://doi.org/10.26508/lsa.202201689
Publikováno v:
J Neuropathol Exp Neurol
Amyotrophic lateral sclerosis (ALS) is characterized by the progressive degeneration of motor neurons. There is a pathological and genetic link between ALS and frontotemporal lobar degeneration (FTLD). Although FTLD is characterized by abnormal phosp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aba988a88b54086ab53a6c95e1f8f208
https://doi.org/10.1093/jnen/nlz041
https://doi.org/10.1093/jnen/nlz041
Autor:
Andrew J. Affleck, Claire E. Shepherd, Glenda M. Halliday, Shelley L. Forrest, Milan Kapur, Andrew B. McGeachie, Marloes van Roijen, Yue Huang, Jillian J. Kril, Ciara V. McGinley, Rachel Tan, Heather McCann, Fiona Bright, Anastasia Sizemova
Publikováno v:
Journal of neuropathology and experimental neurology. 79(10)
This study proposes a practical approach, using the minimum number of brain regions and stains, to consolidate previously published neuropathological criteria into one operationalized schema to differentiate subtypes of frontotemporal lobar degenerat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63b0c846a2d1d34a534f46eed19c0a08
https://pubmed.ncbi.nlm.nih.gov/32954432
https://pubmed.ncbi.nlm.nih.gov/32954432
Publikováno v:
The EMBO Journal
Tau is a scaffolding protein that serves multiple cellular functions that are perturbed in neurodegenerative diseases, including Alzheimer's disease (AD) and frontotemporal dementia (FTD). We have recently shown that amyloid‐β, the second hallmark
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c3dc3b28487d378056c77c7c9858a57
https://pubmed.ncbi.nlm.nih.gov/31268600
https://pubmed.ncbi.nlm.nih.gov/31268600