Zobrazeno 1 - 10 of 14 pro vyhledávání: '"Marloes I, Hofstee"'
1
Akademický článek
Cytomegalovirus and Epstein–Barr virus co-infected young and middle-aged adults can have an aging-related T-cell phenotype
Autor: Marloes I. Hofstee, Alper Cevirgel, Mary-Lène de Zeeuw-Brouwer, Lia de Rond, Fiona van der Klis, Anne-Marie Buisman
Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Cytomegalovirus (CMV) is known to alter circulating effector memory or re-expressing CD45RA+ (TemRA) T-cell numbers, but whether Epstein–Barr virus (EBV) does the same or this is amplified during a CMV and EBV co-infection is unclear. Immu
Externí odkaz: https://doaj.org/article/0935dc23beac478490b7fff6cac90b23
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2
Akademický článek
Efficacy of Bisphosphonate-Conjugated Sitafloxacin in a Murine Model of S. aureus Osteomyelitis: Evidence of 'Target & Release' Kinetics and Killing of Bacteria Within Canaliculi
Autor: Youliang Ren, Thomas Xue, Joshua Rainbolt, Karen L. de Mesy Bentley, Chad A. Galloway, Yuting Liu, Philip Cherian, Jeffrey Neighbors, Marloes I. Hofstee, Frank H. Ebetino, Thomas Fintan Moriarty, Shuting Sun, Edward M. Schwarz, Chao Xie
Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
S. aureus infection of bone is difficult to eradicate due to its ability to colonize the osteocyte-lacuno-canalicular network (OLCN), rendering it resistant to standard-of-care (SOC) antibiotics. To overcome this, we proposed two bone-targeted bispho
Externí odkaz: https://doaj.org/article/bce85e9c2bad40a79c4e87db39e8c0b8
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3
Akademický článek
In Vitro 3D Staphylococcus aureus Abscess Communities Induce Bone Marrow Cells to Expand into Myeloid-Derived Suppressor Cells
Autor: Marloes I. Hofstee, Anja Heider, Sonja Häckel, Caroline Constant, Martijn Riool, R. Geoff Richards, T. Fintan Moriarty, Sebastian A. J. Zaat
Publikováno v: Pathogens, Vol 10, Iss 11, p 1446 (2021)
Staphylococcus aureus is the main causative pathogen of subcutaneous, bone, and implant-related infections, forming structures known as staphylococcal abscess communities (SACs) within tissues that also contain immunosuppressive myeloid-derived suppr
Externí odkaz: https://doaj.org/article/9c002aee20ab48efa46220de3f3e0464
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4
Akademický článek
An Enzybiotic Regimen for the Treatment of Methicillin-Resistant Staphylococcus aureus Orthopaedic Device-Related Infection
Autor: Eric T. Sumrall, Marloes I. Hofstee, Daniel Arens, Christian Röhrig, Susanne Baertl, Dominic Gehweiler, Mathias Schmelcher, Martin J. Loessner, Stephan Zeiter, R. Geoff Richards, T. Fintan Moriarty
Publikováno v: Antibiotics, Vol 10, Iss 10, p 1186 (2021)
Orthopaedic device-related infection (ODRI) presents a significant challenge to the field of orthopaedic and trauma surgery. Despite extensive treatment involving surgical debridement and prolonged antibiotic therapy, outcomes remain poor. This is la
Externí odkaz: https://doaj.org/article/ba5eec9a7e5e465c9a3262f6a01744b6
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6
A murine Staphylococcus aureus fracture-related infection model characterised by fracture non-union, staphylococcal abscess communities and myeloid-derived suppressor cells
Autor: R.G. Richards, F Gieling, Caroline Constant, Martijn Riool, V Stenger, Thomas Fintan Moriarty, Dirk Nehrbass, Stephan Zeiter, Marloes I. Hofstee, S Aj Zaat
Publikováno v: European cells & materials, 41, 771-792. Swiss Society for Biomaterials
European Cells & Materials, Vol 41, Pp 774-792 (2021)
A fracture-related infection (FRI) is a serious complication that can occur after surgical fixation of bone fractures. Affected patients may encounter delayed healing and functional limitations. Although it is well established that Staphylococcus aur
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb194e8cff4285c79177afddf8941441
https://doi.org/10.22203/ecm.v041a49
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7
Current Concepts of Osteomyelitis
Autor: Marloes I. Hofstee, Martin J. Stoddart, Mario Morgenstern, Robert Geoff Richards, Gerald J. Atkins, Martijn Riool, Thomas Fintan Moriarty, Sebastian A. J. Zaat, Keith Thompson, Gowrishankar Muthukrishnan
Publikováno v: The American Journal of Pathology. 190:1151-1163
Osteomyelitis is an inflammation of the bone and bone marrow that is most commonly caused by a Staphylococcus aureus infection. Much of our understanding of the underlying pathophysiology of osteomyelitis, from the perspective of both host and pathog
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::977651cf307af9dac50dba87e38228b6
https://doi.org/10.1016/j.ajpath.2020.02.007
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8
An Enzybiotic Regimen for the Treatment of Methicillin-Resistant Staphylococcus aureus Orthopaedic Device-Related Infection
Autor: Marloes I. Hofstee, Martin J. Loessner, Susanne Baertl, Dominic Gehweiler, Stephan Zeiter, Daniel Arens, Christian Röhrig, Eric T. Sumrall, Mathias Schmelcher, T. Fintan Moriarty, R. Geoff Richards
Publikováno v: Antibiotics, Vol 10, Iss 1186, p 1186 (2021)
Antibiotics
Volume 10
Issue 10
Antibiotics, 10 (10)
Orthopaedic device-related infection (ODRI) presents a significant challenge to the field of orthopaedic and trauma surgery. Despite extensive treatment involving surgical debridement and prolonged antibiotic therapy, outcomes remain poor. This is la
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e0a1150c1b77fcc57833a0fe43fe20e
https://www.mdpi.com/2079-6382/10/10/1186
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9
In Vitro 3D Staphylococcus aureus Abscess Communities Induce Bone Marrow Cells to Expand into Myeloid-Derived Suppressor Cells
Autor: Sonja Häckel, Martijn Riool, Marloes I. Hofstee, Sebastian A. J. Zaat, T. Fintan Moriarty, R. Geoff Richards, Anja Heider, Caroline Constant
Publikováno v: Hofstee, Marloes I; Heider, Anja; Häckel, Sonja; Constant, Caroline; Riool, Martijn; Richards, R Geoff; Moriarty, T Fintan; Zaat, Sebastian A J (2021). In Vitro 3D Staphylococcus aureus Abscess Communities Induce Bone Marrow Cells to Expand into Myeloid-Derived Suppressor Cells. Pathogens, 10(11) MDPI AG 10.3390/pathogens10111446
Pathogens
Pathogens, Vol 10, Iss 1446, p 1446 (2021)
Volume 10
Issue 11
Pathogens (Basel, Switzerland), 10(11):1446. MDPI AG
Staphylococcus aureus is the main causative pathogen of subcutaneous, bone, and implant-related infections, forming structures known as staphylococcal abscess communities (SACs) within tissues that also contain immunosuppressive myeloid-derived suppr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6ec2315e1c43b8143c1b73e92e5d1e7
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10
Three-Dimensional In Vitro Staphylococcus aureus Abscess Communities Display Antibiotic Tolerance and Protection from Neutrophil Clearance
Autor: Marloes I. Hofstee, T. Fintan Moriarty, Igors Terjajevs, Martijn Riool, Martin J. Stoddart, Keith Thompson, R. Geoff Richards, Sebastian A. J. Zaat
Publikováno v: Infection and immunity, 88(11):e00293. American Society for Microbiology
Infect Immun
Staphylococcus aureus is a prominent human pathogen in bone and soft-tissue infections. Pathophysiology involves abscess formation, which consists of central staphylococcal abscess communities (SACs), surrounded by a fibrin pseudocapsule and infiltra
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a304e1a4f26c3c157ad1e64a5eb92da5
https://doi.org/10.1128/iai.00293-20
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