Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Marlin Touma"'
Publikováno v:
Cells, Vol 12, Iss 24, p 2805 (2023)
Long non-coding RNA (lncRNA) mediated transcriptional regulation is increasingly recognized as an important gene regulatory mechanism during development and disease. LncRNAs are emerging as critical regulators of chromatin state; yet the nature and t
Externí odkaz:
https://doaj.org/article/69178a671584423ba413932c305c21a6
Autor:
Theresa Trieu, Philbert Mach, Kaitlyn Bunn, Vincent Huang, Jamie Huang, Christine Chow, Haruko Nakano, Viviana M. Fajardo, Marlin Touma, Shuxun Ren, Yibin Wang, Atsushi Nakano
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
The treatment of atrial fibrillation (AF) continues to be a significant clinical challenge. While genome-wide association studies (GWAS) are beginning to identify AF susceptibility genes (Gudbjartsson et al., Nature, 2007, 448, 353–357; Choi et al.
Externí odkaz:
https://doaj.org/article/68698c67963a4547b5bb3e39a735d407
Autor:
Reiri Sono, Tania M. Larrinaga, Alden Huang, Frank Makhlouf, Xuedong Kang, Jonathan Su, Ryan Lau, Valerie A. Arboleda, Reshma Biniwale, Gregory A. Fishbein, Negar Khanlou, Ming-Sing Si, Gary M. Satou, Nancy Halnon, UCLA Congenital Heart Defects-BioCore Faculty, Glen S. Van Arsdell, Carol C. Gregorio, Stanly Nelson, Marlin Touma
Publikováno v:
Cells, Vol 12, Iss 11, p 1455 (2023)
As an essential component of the sarcomere, actin thin filament stems from the Z-disk extend toward the middle of the sarcomere and overlaps with myosin thick filaments. Elongation of the cardiac thin filament is essential for normal sarcomere matura
Externí odkaz:
https://doaj.org/article/1549951580934b4d81d7ef112d28c224
Autor:
Jamie O. Yang, Hapet Shaybekyan, Yan Zhao, Xuedong Kang, Gregory A. Fishbein, Negar Khanlou, Juan C. Alejos, Nancy Halnon, Gary Satou, Reshma Biniwale, Hane Lee, Glen Van Arsdell, Stanley F. Nelson, Marlin Touma, the UCLA Clinical Genomics Center, the UCLA Congenital Heart Defects-BioCore Faculty
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2022)
We report a case of hypertrophic cardiomyopathy and lactic acidosis in a 3-year-old female. Cardiac and skeletal muscles biopsies exhibited mitochondrial hyperplasia with decreased complex IV activity. Whole exome sequencing identified compound heter
Externí odkaz:
https://doaj.org/article/3249993441454cc5a561ada6b4c8bd1b
Autor:
Fotios Spyropoulos, Sally H. Vitali, Marlin Touma, Chase D. Rose, Carter R. Petty, Philip Levy, Stella Kourembanas, Helen Christou
Publikováno v:
Pulmonary Circulation, Vol 10 (2020)
Echocardiography is the gold standard non-invasive technique to diagnose pulmonary hypertension. It is also an important modality used to monitor disease progression and response to treatment in patients with pulmonary hypertension. Surprisingly, onl
Externí odkaz:
https://doaj.org/article/eb9bafbea5e7486ba427a667ebfbdf58
Autor:
Marlin Touma, Brian Reemtsen, Nancy Halnon, Juan Alejos, J. Paul Finn, Stanley F. Nelson, Yibin Wang
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 4 (2017)
Congenital heart defects (CHDs) affect approximately 1% of live births and are a major source of childhood morbidity and mortality even in countries with advanced healthcare systems. Along with phenotypic heterogeneity, the underlying etiology of CHD
Externí odkaz:
https://doaj.org/article/aff27d8caa9749cdbf231b38255a018b
Autor:
Zubin Mehta, Marlin Touma
Advancements in genomics, bioinformatics and genome editing have uncovered new dimensions in gene regulation. Post-transcriptional modifications by the alternative splicing of mRNA transcripts are critical regulatory mechanisms of mammalian gene expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c11b44ee6c7b1301747d7185a7d0b807
Publikováno v:
Journal of Molecular and Cellular Cardiology. 173:45-46
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5811a5912a292342e507507a71f0053
https://doi.org/10.1016/j.yjmcc.2022.08.091
https://doi.org/10.1016/j.yjmcc.2022.08.091
Publikováno v:
Journal of Molecular and Cellular Cardiology. 173:172-173
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9fc1f18aa470c962576ba601cd9d646
https://doi.org/10.1016/j.yjmcc.2022.08.332
https://doi.org/10.1016/j.yjmcc.2022.08.332
Autor:
Hassan Karami, Marlin Touma, Hossein Mashhadi Abdolahi, Ebrahim Miri-Moghaddam, Nazila Alizadeh, Maryam Moosavi, Afshin Derakhshani, Behzad Baradaran, Khalil Hajiasgharzadeh, Hossein Safarpour
Publikováno v:
Physiology and Pharmacology. 24:298-313
Introduction: Tetralogy of Fallot (TOF) is the most common cyanotic form of congenital heart defects. However, there is no effective therapeutic approach and current therapies have limited curative efficacy. Moreover, the exact etiology of TOF has re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78f1f14c5093ff3397bbdef09984b26d
https://doi.org/10.32598/ppj.24.4.90
https://doi.org/10.32598/ppj.24.4.90