Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Marlin Linger"'
Autor:
Ernest R Chan, Lucas D Jones, Marlin Linger, Jeffrey D Kovach, Maria M Torres-Teran, Audric Wertz, Curtis J Donskey, Peter A Zimmerman
Publikováno v:
PLoS Genetics, Vol 18, Iss 9, p e1010200 (2022)
SARS-CoV-2 whole genome sequencing has played an important role in documenting the emergence of polymorphisms in the viral genome and its continuing evolution during the COVID-19 pandemic. Here we present data from over 360 patients to characterize t
Externí odkaz:
https://doaj.org/article/d4c5ae1052f4453d89a2026ea365e06d
Autor:
Lucas D. Jones, Ernest R. Chan, Jennifer L. Cadnum, Sarah N. Redmond, Maria E. Navas, Trina F. Zabarsky, Elizabeth C. Eckstein, Jeffrey D. Kovach, Marlin Linger, Peter A. Zimmerman, Curtis J. Donskey
Publikováno v:
Infection control and hospital epidemiology.
Objective:To investigate a cluster of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in employees working on 1 floor of a hospital administration building.Methods:Contact tracing was performed to identify potential exposures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb010e5e2e79cbc06fbaf61199e0617d
https://pubmed.ncbi.nlm.nih.gov/35189996
https://pubmed.ncbi.nlm.nih.gov/35189996
Autor:
Melinda Zikursh-Blood, Marlin Linger, Arsène Ratsimbasoa, Rosalind E. Howes, Peter A. Zimmerman, Brune Ramiranirina, Tovonahary Angelo Rakotomanga, Rajeev K. Mehlotra, Stéphanie Ramboarina, D’Arbra Blankenship, Thierry Franchard, Brian T. Grimberg
Publikováno v:
Malaria Journal
Malaria Journal, Vol 16, Iss 1, Pp 1-13 (2017)
Malaria Journal, Vol 16, Iss 1, Pp 1-13 (2017)
Background Plasmodium vivax is the most prevalent human malaria parasite and is likely to increase proportionally as malaria control efforts more rapidly impact the prevalence of Plasmodium falciparum. Despite the prominence of P. vivax as a major hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69c6daba75a1f23be0281c8f4d15809e
https://ora.ox.ac.uk/objects/uuid:e801b647-8b8d-4daf-ad57-d5cea409e114
https://ora.ox.ac.uk/objects/uuid:e801b647-8b8d-4daf-ad57-d5cea409e114
Publikováno v:
Journal of Biological Chemistry. 289:3529-3538
Cytochrome P450 46A1 (CYP46A1) is a brain-specific cholesterol 24-hydroxylase responsible for the majority of cholesterol elimination from the brain. Genetically increased CYP46A1 expression in mice leads to improved cognition and decreases manifesta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::951aa6db0406ece30cd53cde1d97dcf3
https://doi.org/10.1074/jbc.m113.532846
https://doi.org/10.1074/jbc.m113.532846
Autor:
Natalia Mast, Irina A. Pikuleva, Jeffrey S. Wiseman, Matthew Clark, C. David Stout, Marlin Linger
Publikováno v:
Molecular Pharmacology. 82:824-834
Cytochrome P450 46A1 (cholesterol 24-hydroxylase) is an important brain enzyme that may be inhibited by structurally distinct pharmaceutical agents both in vitro and in vivo. To identify additional inhibitors of CYP46A1 among U.S. Food and Drug Admin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7438f463769f39f6248007042309e54
https://doi.org/10.1124/mol.112.080424
https://doi.org/10.1124/mol.112.080424
In vertebrates, the biosynthesis of steroid hormones is initiated by cytochrome P450 CYP11A1 which converts cholesterol to pregnenolone. We investigated whether some of the experimental and FDA-approved therapeutic agents alter the activity of CYP11A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a01c529ebec857f83946e41be040230
https://europepmc.org/articles/PMC3568244/
https://europepmc.org/articles/PMC3568244/