Výsledky vyhledávání - "Marlin Halim"

Fluorescent single-stranded DNA-based assay for detecting unchelated Gadolinium(III) ions in aqueous solution

Autor: Osafanmwen Edogun, Nghia Huu Nguyen, Marlin Halim

Publikováno v: Analytical and Bioanalytical Chemistry. 408:4121-4131

The main concern pertaining to the safety of Gadolinium(III)-based contrast agents (GBCAs) is the toxicity caused by the unchelated ion, which may be inadvertently present in the solution due most commonly to excess unreacted starting material or dis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92958f92f9d54232a68ab5d4906cc973
https://doi.org/10.1007/s00216-016-9503-2

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Novel piperidine-derived amide sEH inhibitors as mediators of lipid metabolism with improved stability

Autor: Shuwei Zhang, Gina Y. Jin, Amir A. Zeki, Christophe Morisseau, Stevan Pecic, Bruce D. Hammock, Shi Xian Deng, Marlin Halim, Sean D. Kodani, Xiaoming Xu

Publikováno v: Prostaglandinsother lipid mediators. 136

We have previously identified and reported several potent piperidine-derived amide inhibitors of the human soluble epoxide hydrolase (sEH) enzyme. The inhibition of this enzyme leads to elevated levels of epoxyeicosatrienoic acids (EETs), which are k

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e305671c75463186981e56064cc45fbf
https://pubmed.ncbi.nlm.nih.gov/29567338

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Recognition and sensing of low-epitope targets via ternary complexes with oligonucleotides and synthetic receptors

Autor: Milan N. Stojanovic, Tilla S. Worgall, Stevan Pecic, Mihaela Barbu, Steven Taylor, Dmitry M. Kolpashchikov, Marlin Halim, Payal Pallavi, Kyung-Ae Yang, Benjamin Kim

Publikováno v: Nature chemistry

Oligonucleotide-based receptors or aptamers can interact with small molecules, but the ability to achieve high-affinity and specificity of these interactions depends strongly on functional groups or epitopes displayed by the binding targets. Some cla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27d5745c7cdfd2442ce9775f43980f59
https://doi.org/10.1038/nchem.2058

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An Aptamer-based Sensor for Unchelated Gadolinium(III)

Autor: Nghia Huu Nguyen, Osafanmwen Edogun, Tracy Y. Chan, Marlin Halim, Anthony Luu

A method for determining the presence of unchelated trivalent gadolinium ion (Gd3+) in aqueous solution is demonstrated. Gd3+ is often present in samples of gadolinium-based contrast agents as a result of incomplete reactions between the ligand and t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d0d1cf4bbfc1a16b98f733f8ad80a00
https://europepmc.org/articles/PMC5409287/

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Imaging Induction of Cytoprotective Enzymes in Intact Human Cells: Coumberone, a Metabolic Reporter for Human AKR1C Enzymes Reveals Activation by Panaxytriol, an Active Component of Red Ginseng

Autor: Marlin Halim, Dalibor Sames, Dominic J. Yee

Publikováno v: Journal of the American Chemical Society. 130:14123-14128

We here present an optical method for monitoring the activity of the inducible aldo-keto reductases AKR1C2 and AKR1C3 in living human cells. The induction of these enzymes is regulated by the antioxidant response element (ARE), as demonstrated in rec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39da3f3e11b69cd7ffd7b8f6ba32cf78
https://doi.org/10.1021/ja801245y

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Two-Photon Excitation of Fluorogenic Probes for Redox Metabolism: Dramatic Enhancement of Optical Contrast Ratio by Two-Photon Excitation

Autor: Vojtech Balsanek, Qingdong Zheng, Dalibor Sames, Paras N. Prasad, Steffen Jockusch, Nicholas J. Turro, Guang S. He, Dominic J. Yee, Haridas E. Pudavar, Marlin Halim

Publikováno v: The Journal of Physical Chemistry C. 111:8872-8877

Fluorogenic probes for redox metabolism are shown to exhibit two-photon absorption using femtosecond pulses from a Ti/sapphire laser. The probes consist of a coumarin or naphthalene core and a ketone−alcohol functional group. The probe design is ba

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4c20d1317dd139b2fd7f2603a3447fce
https://doi.org/10.1021/jp067430h

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Phosphorylation State-Responsive Lanthanide Peptide Conjugates: A Luminescence Switch Based on Reversible Complex Reorganization

Autor: Marlin Halim, Matthew S. Tremblay, Qing Zhu, Dalibor Sames, Joanne Dyer, Angel A. Martí, Steffen Jockusch, Nicholas J. Turro

Publikováno v: Organic Letters. 8:2723-2726

[reaction: see text] A luminogenic probe for peptide dephosphorylation has been developed. It consists of a serine-/tyrosine-containing peptide modified on the N-terminus with a tryptophan residue and a DTPA chelate capable of binding Tb(3+). We prop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b85694ff5c6624b345ec164c91c10103
https://doi.org/10.1021/ol060614u

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Dynamic properties and optical phase conjugation of two-photon pumped ultrashort blue stimulated emission in a chromophore solution

Autor: Marlin Halim, Dalibor Sames, Paras N. Prasad, Hans Ågren, Guang S. He, Nicholas J. Turro, Sailing He, Steffen Jockusch, Qingdong Zheng, Haiyan Qin

Publikováno v: Physical Review A. 77

The dynamic properties of two-photon pumped blue lasing (similar to 470 nm) in the solution of an organic chromophore [2-acetyl-6-(dimethylamino)naphthalene], excited by similar to 160-fs laser pul ...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fb8edbf81e690bf2465d84efd0631b91
https://doi.org/10.1103/physreva.77.013824

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