Výsledky vyhledávání - "Marlies Knaup Reymond"

Akademický článek

Innate immune sensing of modified vaccinia virus Ankara (MVA) is mediated by TLR2-TLR6, MDA-5 and the NALP3 inflammasome.

Autor: Julie Delaloye, Thierry Roger, Quynh-Giao Steiner-Tardivel, Didier Le Roy, Marlies Knaup Reymond, Shizuo Akira, Virginie Petrilli, Carmen E Gomez, Beatriz Perdiguero, Jürg Tschopp, Giuseppe Pantaleo, Mariano Esteban, Thierry Calandra

Publikováno v: PLoS Pathogens, Vol 5, Iss 6, p e1000480 (2009)

Modified vaccinia virus Ankara (MVA) is an attenuated double-stranded DNA poxvirus currently developed as a vaccine vector against HIV/AIDS. Profiling of the innate immune responses induced by MVA is essential for the design of vaccine vectors and fo

Externí odkaz: https://doaj.org/article/7bb436f334c746208e44d4a2413dacee

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A functional microsatellite of the macrophage migration inhibitory factor gene associated with meningococcal disease

Autor: Michael Levin, Marcel van Deuren, Fred C.G.J. Sweep, Elene Haralambous, Helen Betts, Murielle Bochud, Veronique Erard, Tom Sprong, Robert C. Read, Elliott Mermel, Thierry Roger, Pascal Renner, Thierry Calandra, Saul N. Faust, Pierre-Yves Bochud, Anne-Laure Chanson, Marlies Knaup Reymond

Publikováno v: FASEB journal : official publication of the Federation of American Societies for Experimental Biolog
FASEB JOURNAL
The Faseb Journal, 26, 907-16
The Faseb Journal, 26, 2, pp. 907-16
The FASEB journal : official publication of the Federation of American Societies for Experimental Bi

Macrophage migration inhibitory factor (MIF) is an abundantly expressed proinflammatory cytokine playing a critical role in innate immunity and sepsis and other inflammatory diseases. We examined whether functional MIF gene polymorphisms ( 794 CATT(5

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65f2b72f78a9e94c5a27e44957860286

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Histone deacetylase inhibitors impair innate immune responses to Toll-like receptor agonists and to infection

Autor: Didier Le Roy, Xavier C. Ding, Anne-Laure Chanson, Geneviève Goy, Jacques Schrenzel, Jérôme Lugrin, Thibaud Koessler, Thierry Roger, Thierry Calandra, Marlies Knaup Reymond, Matteo Mombelli, Patrice Francois, Isabelle Miconnet

Publikováno v: Blood, Vol. 117, No 4 (2011) pp. 1205-17
BLOOD
Blood

Regulated by histone acetyltransferases and deacetylases (HDACs), histone acetylation is a key epigenetic mechanism controlling chromatin structure, DNA accessibility, and gene expression. HDAC inhibitors induce growth arrest, differentiation, and ap

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::519a82183d32070b1234ffe5e605a1d9
https://doi.org/10.1182/blood-2010-05-284711

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Estradiol and progesterone strongly inhibit the innate immune response of mononuclear cells in newborns

Autor: Matthieu Perreau, Matthias Roth-Kleiner, Eric Giannoni, Laurence Guignard, Marlies Knaup Reymond, Thierry Calandra, Thierry Roger

Publikováno v: Infection and immunity
INFECTION AND IMMUNITY

Newborns are particularly susceptible to bacterial infections due to qualitative and quantitative deficiencies of the neonatal innate immune system. However, the mechanisms underlying these deficiencies are poorly understood. Given that fetuses are e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::758b0f05d680282ca1caf89dff75f100

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Role of MyD88 and Toll-like receptors 2 and 4 in the sensing of Parachlamydia acanthamoebae

Autor: Gilbert Greub, Thierry Roger, Thierry Calandra, José M. Entenza, Nicola Casson, Shizuo Akira, Marlies Knaup Reymond, Didier Le Roy, Marc Pusztaszeri, Antony Croxatto

Publikováno v: Infection and immunity

Parachlamydia acanthamoebae is a Chlamydia -related organism whose pathogenic role in pneumonia is supported by serological and molecular clinical studies and an experimental mouse model of lung infection. Toll-like receptors (TLRs) play a seminal ro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7ac06adee63a3ecd2d53ccf3dfa6172

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Protection from lethal gram-negative bacterial sepsis by targeting Toll-like receptor 4

Autor: Thierry Calandra, Didier Le Roy, Shizuo Akira, Davide Mauri, Anne-Laure Chanson, Kim Burns, Thierry Roger, Beat M. Riederer, Céline Froidevaux, Marlies Knaup Reymond

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America

Toll-like receptor 4 (TLR4), the signal-transducing molecule of the LPS receptor complex, plays a fundamental role in the sensing of LPS from Gram-negative bacteria. Activation of TLR4 signaling pathways by LPS is a critical upstream event in the pat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cb95b4aa068e3176d0e4fd44e227d50

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Macrophage migration inhibitory factor promotes innate immune responses by suppressing glucocorticoid-induced expression of mitogen-activated protein kinase phosphatase-1

Autor: Marlies Knaup-Reymond, Anne Laure Chanson, Thierry Roger, Thierry Calandra

Publikováno v: European Journal of Immunology. 35:3405-3413

The pro-inflammatory cytokine macrophage migration inhibitory factor (MIF) acts as a physiological counter-regulator of the immuno-suppressive effects of glucocorticoids. However, the mechanisms whereby MIF exerts its counter-balancing effect remain

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38badd94629edcc7c92876f4d790a77c
https://doi.org/10.1002/eji.200535413

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Innate Immune Sensing of Modified Vaccinia Virus Ankara (MVA) Is Mediated by TLR2-TLR6, MDA-5 and the NALP3 Inflammasome

Autor: Shizuo Akira, Carmen E. Gómez, Giuseppe Pantaleo, Virginie Pétrilli, Beatriz Perdiguero, Mariano Esteban, Jürg Tschopp, Julie Delaloye, Didier Le Roy, Quynh-Giao Steiner-Tardivel, Marlies Knaup Reymond, Thierry Calandra, Thierry Roger

Publikováno v: PLoS Pathogens
PLoS pathogens
PLoS Pathogens, Vol 5, Iss 6, p e1000480 (2009)
PLoS Pathogens, vol. 5, no. 6, pp. e1000480

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c18782b61205febf7471da963b6ebaab
http://europepmc.org/articles/PMC2691956

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Increased macrophage migration inhibitory factor (MIF) plasma levels in acute HIV-1 infection

Autor: Thierry Calandra, Fred C.G.J. Sweep, Marlies Knaup Reymond, Thierry Roger, Julie Delaloye, Katharine E A Darling, Matthias Cavassini, Irma J.A. De Bruin

Publikováno v: Cytokine
Cytokine, 60, 2, pp. 338-40
CYTOKINE
Cytokine, 60, 338-40

Item does not contain fulltext Considering macrophage migratory inhibitory factor (MIF) as a critical pro-inflammatory cytokine of the immune system, we evaluated plasma MIF levels in 89 HIV-infected adults. Plasma MIF levels were higher in HIV-infec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c043332897deb4226a273a5b076ac685

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