Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Marlies Kimpe"'
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24275 (2011)
Several nutrient permeases have been identified in yeast, which combine a transport and receptor function, and are called transceptors. The Gap1 general amino acid permease and the Mep2 ammonium permease mediate rapid activation by amino acids and by
Externí odkaz:
https://doaj.org/article/a79de71865844731be71ad74763738a9
Autor:
Johan M. Thevelein, Zhiqiang Zhang, Harish Nag Kankipati, Michaela Conrad, Marlies Kimpe, Griet Van Zeebroeck
Publikováno v:
FEMS Yeast Research
Two nutrient-controlled signalling pathways, the PKA and TOR pathway, play a major role in nutrient regulation of growth as well as growth-correlated properties in yeast. The relationship between the two pathways is not well understood. We have used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::853664a6faae20ae89a0c051bd472f08
https://doi.org/10.1093/femsyr/fox048
https://doi.org/10.1093/femsyr/fox048
Publikováno v:
Biochemical and Biophysical Research Communications. 419:89-94
The yeast Saccharomyces cerevisiae responds to amino acid deprivation by increasing translation of the transcription factor Gcn4, which enhances expression of amino acid biosynthetic genes. Accumulation of uncharged tRNAs activates the Gcn2 protein k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bbfc3ebe5c1b082a5ebaa9a6f0594c0
https://doi.org/10.1016/j.bbrc.2012.01.133
https://doi.org/10.1016/j.bbrc.2012.01.133
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 73:904-912
Purpose Investigations of epigenetic drugs have shown that radiotherapy can be successfully combined with histone deacetylase inhibitors (HDAC-Is) for the treatment of head-and-neck squamous cell carcinoma (HNSCC). Whether the reversal of epigenetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::988d41a347f8e9b15670643eba619b0c
https://doi.org/10.1016/j.ijrobp.2008.10.032
https://doi.org/10.1016/j.ijrobp.2008.10.032
Autor:
Matthias Versele, Karin Voordeckers, Steven Haesendonckx, Wendy Louwet, Marlies Kimpe, Johan M. Thevelein
Publikováno v:
The Journal of biological chemistry. 286(25)
Pkh1, -2, and -3 are the yeast orthologs of mammalian 3-phosphoinositide-dependent protein kinase-1 (PDK1). Although essential for viability, their functioning remains poorly understood. Sch9, the yeast protein kinase B and/or S6K ortholog, has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfb755fd93392a74de3d17e47f6e377d
https://pubmed.ncbi.nlm.nih.gov/21531713
https://pubmed.ncbi.nlm.nih.gov/21531713
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24275 (2011)
PLoS ONE
PLoS ONE
Several nutrient permeases have been identified in yeast, which combine a transport and receptor function, and are called transceptors. The Gap1 general amino acid permease and the Mep2 ammonium permease mediate rapid activation by amino acids and by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0be7fe5da45d6bc41693ffea7e6870bb
https://doi.org/10.1371/journal.pone.0024275
https://doi.org/10.1371/journal.pone.0024275