Zobrazeno 1 - 10 of 11 pro vyhledávání: '"Marlies Goetz"'
1
Enhanced stimulation of antigen-specific immune responses against nucleophosmin 1 mutated acute myeloid leukaemia by an anti-programmed death 1 antibody
Autor: Jochen Greiner, Marlies Goetz, Patrick J. Schuler, Christiane Bulach, Susanne Hofmann, Hubert Schrezenmeier, Harmut Dӧhner, Vanessa Schneider, Barbara‐ann Guinn
Publikováno v: British journal of haematologyREFERENCES. 198(5)
Nucleophosmin1 (NPM1) is one of the most commonly mutated genes in AML and is often associated with a favourable prognosis. Immune responses play an increasing role in AML treatment decisions; however, the role of immune checkpoint inhibition is stil
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dd736557face8689f53b17be62cd04d
https://pubmed.ncbi.nlm.nih.gov/35799423
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3
Cytomegalovirus vaccination of leukemia and lymphoma patients after allogeneic stem cell transplantation--validation of a peptide vaccine
Autor: Michael Schmitt, Junxia Yao, Birgit Maccari, Anita Schmitt, Clemens Bechter, Marlies Goetz, Markus Wiesneth, Peter Schauwecker
Publikováno v: Journal of immunological methods. 343(2)
Peptide vaccination constitutes a novel immunotherapeutical approach for the treatment of patients with solid tumors, lymphoma and leukemia. Moreover it might be of use in hematooncological patients for the prevention and therapy of infections like c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f57e3d90d962ce88461bc760ea6e10ff
https://pubmed.ncbi.nlm.nih.gov/19248785
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4
Cytotoxic T-Lymphocytes Recognize and Target Leukemic Stem Cells
Autor: Lars Bullinger, Hartmut Doehner, Susanne Hofmann, Markus Rojewski, Lu Zhang, Christian Buske, Vanessa Schneider, Konstanze Doehner, Marlies Goetz, Jochen Greiner
Publikováno v: Blood. 124:5783-5783
Leukemic stem cells (LSC) might be the source for leukemic disease self-renewal and account for disease relapse after treatment, which makes them a critical target for further therapeutic options. Treatment for acute myeloid leukemia (AML) patients b
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::79b31d60d66adbe9e07bda0fc0dd31a0
https://doi.org/10.1182/blood.v124.21.5783.5783
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5
Analysis Of Leukemic Stem Cell Population Comparing NPM1wt and NPM1mut AML Patients and Potential Therapeutic Targets
Autor: Ulla Botzenhardt, Markus Rojewski, Konstanze Doehner, Thomas F. E. Barth, Hubert Schrezenmeier, Hartmut Doehner, Markus Wiesneth, Susanne Hofmann, Jochen Greiner, Lars Bullinger, Lu Zhang, Vanessa Schneider, Marlies Goetz
Publikováno v: Blood. 122:2624-2624
Treatment of acute myeloid leukemia (AML) patients became more effective, yet the relapse rate is still high and cure rate still low. Different therapeutic approaches, based on molecular targeting are offering new treatment strategies using markers l
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7574aa1669c7a8e6009ce6a7686d1eae
https://doi.org/10.1182/blood.v122.21.2624.2624
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6
Effect of epitopes derived from the mutated region of cytoplasmatic nucleophosmine 1 (NPM1) on CD4+ and CD8+ T-cell responses in patients with acute myeloid leukemia
Autor: Elmar Mehring, Vanessa Schneider, Marlies Goetz, Anita Schmitt, Hartmut Döhner, Jochen Greiner, Yoko Ono, Lu Zhang, Joannis Mytilineos, Konstanze Döhner, Markus Wiesneth, Susanne Hofmann, Michael Schmitt
Publikováno v: Journal of Clinical Oncology. 30:6567-6567
6567 Background: Mutations of the nucleophosmin gene (NPM1mut) are one of the most frequent molecular alterations in AML and constitute an important prognostic marker. The impact of NPM1mut on leukemogenesis and progression remains to be elucidated.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2492e5f27676fc9d5eb63ad924333fd2
https://doi.org/10.1200/jco.2012.30.15_suppl.6567
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7
Implications of specific T-cell responses by different novel and known immunogenic tumor-associated antigens (TAA) in patients with metastatic lung cancer
Autor: M. Steinhauser, Susanne Hofmann, Vanessa Schneider, Marlies Goetz, Jochen Greiner, Lu Zhang, A. M. Babiak, J. Conzelmann, Hartmut Döhner
Publikováno v: Journal of Clinical Oncology. 29:10619-10619
10619 Background: In the last years, new therapeutic strategies of lung cancer with encouraging results have been investigated including immunotherapeutic approaches, e.g. against MAGE-A3 and hTERT...
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6b8766d376845d138a4a021c3197970e
https://doi.org/10.1200/jco.2011.29.15_suppl.10619
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10
Peptide Vaccine Preparation and Validation with a Bio-Assay
Autor: Marlies Goetz, Michael Schmitt, Anita Schmitt, Markus Wiesneth, Junxia Yao, Peter Schauwecker, Clemens Bechter, Birgit Maccari
Publikováno v: Blood. 112:5444-5444
Introduction: Peptide vaccination constitutes a novel immunotherapeutical approach for the treatment of patients with solid tumors, lymphoma and leukemia. Moreover it might be of use in hematooncological patients for the prevention and therapy of inf
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8d79acc019f7b8068e17df82ea73074c
https://doi.org/10.1182/blood.v112.11.5444.5444
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