Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Marlies, Michl"'
Autor:
Leah Schöckel, Christine Woischke, Sai Agash Surendran, Marlies Michl, Tobias Schiergens, Andreas Hölscher, Florian Glass, Peter Kreissl, Frederick Klauschen, Michael Günther, Steffen Ormanns, Jens Neumann
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Peroxisome proliferator-activated receptor gamma (PPARG) is a member of the nuclear receptor family. It is involved in the regulation of adipogenesis, lipid metabolism, insulin sensitivity, vascular homeostasis and inflammation. I
Externí odkaz:
https://doaj.org/article/fbd9b366741e4083a7742220f1b68483
Autor:
Sophie L. Boos, Leon P. Loevenich, Sebastian Vosberg, Thomas Engleitner, Rupert Öllinger, Jörg Kumbrink, Matjaz Rokavec, Marlies Michl, Philipp A. Greif, Andreas Jung, Heiko Hermeking, Jens Neumann, Thomas Kirchner, Roland Rad, Peter Jung
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 2, Pp 517-540 (2022)
Background & Aims: Patient-derived tumor organoids recapitulate the characteristics of colorectal cancer (CRC) and provide an ideal platform for preclinical evaluation of personalized treatment options. We aimed to model the acquisition of chemotoler
Externí odkaz:
https://doaj.org/article/916bf465e7144cfd8d6002ff3bbfa24f
Autor:
Sven Jacob, Florian Bösch, Markus B. Schoenberg, Elise Pretzsch, Christopher Lampert, Ren Haoyu, Bernhard W. Renz, Marlies Michl, Jörg Kumbrink, Thomas Kirchner, Jens Werner, Martin K. Angele, Jens Neumann
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract Background Molecular differences in colorectal cancer (CRC) are associated with the metastatic route. Patient survival is mainly driven by metastatic spread thus it is imperative to understand its key drivers to develop biomarkers for risk s
Externí odkaz:
https://doaj.org/article/80c7cc8532c74acdb1342db764e9e655
Autor:
Vanessa Dietinger, Cira R. García de Durango, Svenja Wiechmann, Sophie L. Boos, Marlies Michl, Jens Neumann, Heiko Hermeking, Bernhard Kuster, Peter Jung
Publikováno v:
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-24 (2020)
Abstract Background Wnt signaling drives epithelial self-renewal and disease progression in human colonic epithelium and colorectal cancer (CRC). Characterization of Wnt effector pathways is key for our understanding of these processes and for develo
Externí odkaz:
https://doaj.org/article/fd5a7a6483cd4180b87e3763382c2da5
Autor:
Leon P. Loevenich, Thomas Engleitner, Marlies Michl, Sebastian Vosberg, Matjaz Rokavec, Andreas Jung, Heiko Hermeking, Philipp A. Greif, Jens Neumann, Jörg Kumbrink, Roland Rad, Thomas Kirchner, Peter Jung, Rupert Öllinger, Sophie L. Boos
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 2, Pp 517-540 (2022)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Patient-derived tumor organoids recapitulate the characteristics of colorectal cancer (CRC) and provide an ideal platform for preclinical evaluation of personalized treatment options. We aimed to model the acquisition of chemotolera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::230937cfbfdbfc2312a8988f38a35f08
http://www.sciencedirect.com/science/article/pii/S2352345X21002228
http://www.sciencedirect.com/science/article/pii/S2352345X21002228
Autor:
Arndt Stahler, Sebastian Stintzing, Jobst C. von Einem, Christoph B. Westphalen (Benedikt), Kathrin Heinrich, Nicole Krämer, Marlies Michl, Dominik P. Modest, Ludwig Fischer von Weikersthal, Thomas Decker, Alexander Kiani, Tobias Heintges, Christoph Kahl, Frank Kullmann, Werner Scheithauer, Markus Moehler, Florian Kaiser, Thomas Kirchner, Andreas Jung, Volker Heinemann
Publikováno v:
European Journal of Cancer. 169:223-225
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::591767f775fe1d622a7ae12980cc66ff
https://doi.org/10.1016/j.ejca.2022.04.003
https://doi.org/10.1016/j.ejca.2022.04.003
Autor:
Jörg Kumbrink, Lisa Bohlmann, Soulafa Mamlouk, Torben Redmer, Daniela Peilstöcker, Pan Li, Sylvie Lorenzen, Hana Algül, Stefan Kasper, Dirk Hempel, Florian Kaiser, Marlies Michl, Harald Bartsch, Jens Neumann, Frederick Klauschen, Michael von Bergwelt-Baildon, Dominik Paul Modest, Arndt Stahler, Sebastian Stintzing, Andreas Jung, Thomas Kirchner, Reinhold Schäfer, Volker Heinemann, Julian W. Holch
Publikováno v:
Cancers; Volume 14; Issue 15; Pages: 3631
CA extern Simple Summary The emergence of resistant cells remains a major obstacle for chemotherapy treatment of metastatic colorectal cancers. Improvement of the therapeutic response requires a thorough understanding of the mechanisms of resistance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a29e7644a7df3a11c51a312ace6a0df
Autor:
Jens Neumann, Marlies Michl, F. Taverna, Tobias S. Schiergens, Volker Heinemann, Thomas Kirchner, Jörg Kumbrink, Jutta Engel
Publikováno v:
Virchows Archiv
Metastatic spread is the most important life-threatening feature of colorectal cancer and is supposed to be mainly driven by alterations in different carcinogenic pathways. The present study compared mutation and expression profiles of distinctive bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cfb899ba527d63bcd179e870e0468df
https://doi.org/10.1007/s00428-020-02983-6
https://doi.org/10.1007/s00428-020-02983-6
Autor:
Elise Pretzsch, Florian Bösch, Marlies Michl, Martin K. Angele, Ren Haoyu, Jörg Kumbrink, Sven Jacob, Jens Werner, Christopher Lampert, Jens Neumann, Bernhard W. Renz, Thomas Kirchner, Markus B. Schoenberg
Publikováno v:
BMC Cancer
BMC Cancer, Vol 21, Iss 1, Pp 1-9 (2021)
BMC Cancer, Vol 21, Iss 1, Pp 1-9 (2021)
Background Molecular differences in colorectal cancer (CRC) are associated with the metastatic route. Patient survival is mainly driven by metastatic spread thus it is imperative to understand its key drivers to develop biomarkers for risk stratifica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e75f039e71ea8fd1cbbb93715698bbec
https://doi.org/10.1186/s12885-021-08927-w
https://doi.org/10.1186/s12885-021-08927-w
Autor:
P Paprottka, Tobias Geith, Harun Ilhan, Andrei Todica, Jonathan Nadjiri, Franziska Galiè, Marlies Michl, Michael Ingrisch, Karolin J. Paprottka
Publikováno v:
Cancers
Cancers, Vol 13, Iss 5399, p 5399 (2021)
Cancers; Volume 13; Issue 21; Pages: 5399
Cancers, Vol 13, Iss 5399, p 5399 (2021)
Cancers; Volume 13; Issue 21; Pages: 5399
Simple Summary TARE with yttrium-90 (90Y) resin microspheres is emerging in many countries as a treatment option for ICC. Identification of patients that will benefit from TARE is a clinically relevant problem with individual but also economical rele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91b731bab456542b3af6f9df2b4b245b
http://europepmc.org/articles/PMC8582544
http://europepmc.org/articles/PMC8582544