Zobrazeno 1 - 10 of 11 pro vyhledávání: '"Marlieke Molendijk"'
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Akademický článek
Dendritic Cell-Specific Deletion of β-Catenin Results in Fewer Regulatory T-Cells without Exacerbating Autoimmune Collagen-Induced Arthritis.
Autor: C Henrique Alves, Julia L Ober-Blöbaum, Inge Brouwers-Haspels, Patrick S Asmawidjaja, Adriana M C Mus, Wida Razawy, Marlieke Molendijk, Björn E Clausen, Erik Lubberts
Publikováno v: PLoS ONE, Vol 10, Iss 11, p e0142972 (2015)
Dendritic cells (DCs) are professional antigen presenting cells that have the dual ability to stimulate immunity and maintain tolerance. However, the signalling pathways mediating tolerogenic DC function in vivo remain largely unknown. The β-catenin
Externí odkaz: https://doaj.org/article/9428c4f3c3c74c9aa54084fc08c4e187
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2
AB0128 Cxcl1, but not auto-antibodies or cd4+ccr6+ memory th cells within blood, is a marker to differentiate mice into collagen induced arthritispositive or negative prior to clinically manifest disease
Autor: Amc Mus, Marlieke Molendijk, Erik Lubberts, Patrick S. Asmawidjaja
Publikováno v: Rheumatoid arthritis – etiology, pathogenesis and animal models.
Background There is currently a knowledge gap on early pathogenesis prior to Rheumatoid Arthritis (RA) diagnosis. Additionally, current medication available for RA treatment has not been developed for prevention. Collagen induced arthritis (CIA) coul
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a71af351d9b9e511f916c5124daf9818
https://doi.org/10.1136/annrheumdis-2018-eular.6554
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3
THU0086 Interleukin 17 receptor d (IL-17RD) reduces incidence of collagen induced arthritis
Autor: Marlieke Molendijk, Patrick S. Asmawidjaja, Erik Lubberts, Amc Mus, Dominique Baeten
Publikováno v: THURSDAY, 14 JUNE 2018.
Background IL-17RD is a member of the IL-17 receptor family. In contrast to the other IL-17 receptors, IL-17RA, -RB, -RC and -RE, little is known about the ligand and function of IL-17RD. Recently, IL-17RD has been described to negatively regulate a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::944fcee60585f691180b627853d1aae0
https://doi.org/10.1136/annrheumdis-2018-eular.7117
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4
From patients with arthralgia, pre-RA and recently diagnosed RA: what is the current status of understanding RA pathogenesis?
Autor: Erik Lubberts, Johanna M. W. Hazes, Marlieke Molendijk
Publikováno v: RMD Open, 4(1):UNSP e000256. BMJ Publishing Group
RMD Open
It is believed that therapy for rheumatoid arthritis (RA) is the most effective and beneficial within a short time frame around RA diagnosis. This insight has caused a shift from research in patients with established RA to patients at risk of develop
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::601e96f6c30dd162a9d68f6109f46618
https://pure.eur.nl/en/publications/c67c8424-b1c8-486d-a114-53fc4d4384ae
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5
02.20 Regulation of interleukin 17 receptor d (il17rd) in synovial fibroblasts from rheumatoid arthritis patients and its function in collagen induced arthritis
Autor: Erik Lubberts, Adriana M. C. Mus, Patrick S. Asmawidjaja, Marlieke Molendijk
Publikováno v: New players and novel targets in inflammation.
Background IL17RD is a member of the IL17 receptor family. In contrast to the other IL17 receptors, IL17RA, -RB, -RC and -RE, little is known about the ligand and function of IL17RD. Recently, IL17RD has been described to negatively regulate a select
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bb3fad956c03cd2e99830d7ae45566b8
https://doi.org/10.1136/annrheumdis-2016-211050.20
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6
08.14 IL-23 receptor signalling is critical in normal bone remodelling and influences osteoclast activity in vitro and t cell-driven inflammatory bone damage in vivo
Autor: Adriana M. C. Mus, Wida Razawy, Bram C. J. van der Eerden, Marlieke Molendijk, Marijke Schreuders-Koedam, Vijay K. Kuchroo, Erik Lubberts, Mohamed Oukka, Patrick S. Asmawidjaja
Publikováno v: Autoimmune inflammation.
Background The interleukin (IL)−23/IL-17A immune pathway is critical for the development of autoimmune arthritis. Moreover, systemic exposure of IL-23 induced chronic arthritis, increased osteoclast differentiation and systemic bone loss in mice. H
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8ca1a6b9b33ef21115599e719ae5fdee
https://doi.org/10.1136/annrheumdis-2016-211055.14
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7
Experimental Arthritis Mouse Models Driven by Adaptive and/or Innate Inflammation
Autor: Patrick S. Asmawidjaja, Wida Razawy, Adriana M. C. Mus, Marlieke Molendijk, Celso H. Alves, Erik Lubberts
Publikováno v: Inflammation ISBN: 9781493967841
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease mainly affecting synovial joints. The clinical presentation of RA shows the heterogeneity of this disease with its underlying complex interactions between the innate and adaptive immu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3aa4061bd25e8c5a4bca854e333ee1b3
https://doi.org/10.1007/978-1-4939-6786-5_27
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8
Dendritic Cell-Specific Deletion of β-Catenin Results in Fewer Regulatory T-Cells without Exacerbating Autoimmune Collagen-Induced Arthritis
Autor: Wida Razawy, Erik Lubberts, Inge Brouwers-Haspels, Björn E. Clausen, Adriana M. C. Mus, Marlieke Molendijk, C. Henrique Alves, Patrick S. Asmawidjaja, Julia L. Ober-Blöbaum
Publikováno v: PLoS ONE, Vol 10, Iss 11, p e0142972 (2015)
PLoS One (print), 10(11). Public Library of Science
PLoS ONE
Dendritic cells (DCs) are professional antigen presenting cells that have the dual ability to stimulate immunity and maintain tolerance. However, the signalling pathways mediating tolerogenic DC function in vivo remain largely unknown. The beta-caten
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e82560aef9515f890619965ac0353072
http://europepmc.org/articles/PMC4654567?pdf=render
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9
A3.08 Exploring the collagen induced arthritis model for arthralgia
Autor: Marlieke Molendijk, Erik Lubberts, Patrick S. Asmawidjaja, Chf Alves, Wida Razawy, Amc Mus
Publikováno v: Annals of the Rheumatic Diseases. 75:A35.2-A35
Background and objectives Rheumatoid arthritis (RA) is preceded by a period where the patients experience pain but no clinically apparent arthritis can be detected yet. Without treatment RA can lead to severely inflamed joints and bone damage. Early
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::95da5df562421702927f685ec229ba41
https://doi.org/10.1136/annrheumdis-2016-209124.85
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10
A2.31 Immunisation with type II collagen (CII) alters the IL-23 receptor expression profile compared to naïve conditions
Autor: Marlieke Molendijk, Patrick S. Asmawidjaja, Wida Razawy, Erik Lubberts, Amc Mus, Wendy Dankers, Celina Alves, Vijay K. Kuchroo, Mohamed Oukka
Publikováno v: Annals of the Rheumatic Diseases. 75:A27.3-A28
Background and objectives Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease characterised by synovial infiltration of pro-inflammatory cells. In RA, the interleukin-23/17A (IL-23/IL-17A) pathway plays a central role. While in human R
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::245acdc8c46dca24a6aa8310a7f18998
https://doi.org/10.1136/annrheumdis-2016-209124.66
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