Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Marlese Koehnlein"'
Autor:
Lauren R. Corulli, Denise L. Cecil, Ekram Gad, Marlese Koehnlein, Andrew L. Coveler, Jennifer S. Childs, Ronald A. Lubet, Mary L. Disis
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundOverexpression of nonmutated proteins involved in oncogenesis is a mechanism by which such proteins become immunogenic. We questioned whether overexpressed colorectal cancer associated proteins found at higher incidence and associated with
Externí odkaz:
https://doaj.org/article/3015375de6f44692a214a513d19c7329
Autor:
Shyra Gardai, Nicole M. Okeley, Denise L. Cecil, Mary L. Disis, Marlese Koehnlein, Lauren R. Corulli, Ekram Gad, Peter D. Senter
Publikováno v:
Molecular cancer therapeutics. 19(5)
2-fluorofucose (2FF) inhibits protein and cellular fucosylation. Afucosylation of IgG antibodies enhances antibody-dependent cell-mediated cytotoxicity by modulating antibody affinity for FcγRIIIa, which can impact secondary T-cell activation. Immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80a7c2648cf3dd9e6d9e1bc34347e909
https://pubmed.ncbi.nlm.nih.gov/32165557
https://pubmed.ncbi.nlm.nih.gov/32165557
Autor:
Piper M. Treuting, Sasha E. Stanton, Meredith Slota, Marlese Koehnlein, Lauren Rastetter, Mary L. Disis, Ekram Gad, Yushe Dang
Publikováno v:
Breast Cancer Research and Treatment. 148:501-510
Recent studies in patients with breast cancer suggest the immune microenvironment influences response to therapy. We aimed to evaluate the relationship between growth rates of tumors in common spontaneous mammary tumor models and immune biomarkers ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f956a4d27950020bdac73d0fe792d4b0
https://doi.org/10.1007/s10549-014-3199-9
https://doi.org/10.1007/s10549-014-3199-9
Autor:
Mary L. Disis, Ekram Gadd, Marlese Koehnlein, Piper M. Treuting, Sasha E. Stanton, Lauren Rastetter, Meredith Slota
Publikováno v:
Cancer Research. 73:P2-05
The role of the tumor immune environment is critical in human breast cancer tumorigenesis and response to therapy: tumors with a Th1 immune activating environment (high cytotoxic CD8+ T cells and low FoxP3 and myeloid derived suppressor cells (MDSC))
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1998b028f77e1a903495edca891d9a00
https://doi.org/10.1158/0008-5472.sabcs13-p2-05-03
https://doi.org/10.1158/0008-5472.sabcs13-p2-05-03
Autor:
Lauren Rastetter, John B. Liao, Kelsie J Ovenell, Mary L. Disis, Erin E M Curtis, Denise L. Cecil, Marlese Koehnlein, Ekram Gad
Publikováno v:
Journal for Immunotherapy of Cancer
Background Ovarian cancer is immunogenic and residual tumor volume after surgery is known to be prognostic. Ovarian cancer often follows a recurring-remitting course and microscopic disease states may present ideal opportunities for immune therapies.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3922e07986335b52c45b85382c13e42
https://doi.org/10.1186/s40425-015-0060-6
https://doi.org/10.1186/s40425-015-0060-6
Autor:
Marlese Koehnlein, Dan Herendeen, Mary L. Disis, Ekram Gad, Lauren Rastetter, Dominick L. Auci, Ben Curtis
Publikováno v:
Journal for Immunotherapy of Cancer
Meeting abstracts Many mouse models of breast cancer have been developed that closely replicate human breast cancer subtypes at the genomic level. In order to develop vaccines that could prevent a broad spectrum of breast cancer subtypes, a combinati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60606709429fa9e62ffe762ebd0c1d10
https://doi.org/10.1186/2051-1426-1-s1-p217
https://doi.org/10.1186/2051-1426-1-s1-p217
Autor:
Denise L. Cecil, Dan Herendeen, Megan M. O'Meara, Marlese Koehnlein, Ekram Gad, Meredith Slota, Yushe Dang, Mary L. Disis, Lauren Rastetter
Publikováno v:
Journal for Immunotherapy of Cancer
The high rates of relapse in triple negative breast cancer (TNBC) are thought to be due to the presence of increased levels of cancer stem cells (CSC), which have been shown to be resistant to standard therapies. It has been demonstrated that hypoxia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01df38559a5ceaf23d33d1eb65c8cf3b
http://europepmc.org/articles/PMC4288342
http://europepmc.org/articles/PMC4288342