Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Marlese A, Pisegna"'
Autor:
Marco Napoli, Xiaobo Li, Hayley D. Ackerman, Avani A. Deshpande, Ivan Barannikov, Marlese A. Pisegna, Isabelle Bedrosian, Jürgen Mitsch, Philip Quinlan, Alastair Thompson, Kimal Rajapakshe, Cristian Coarfa, Preethi H. Gunaratne, Douglas C. Marchion, Anthony M. Magliocco, Kenneth Y. Tsai, Elsa R. Flores
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Mutations in TP53 and hyperactivation of the PI3K/AKT pathway are the two most frequent drivers of cancer progression across multiple human tumour types. Here, the authors identify two TAp63 regulated long non-coding RNAs, TROLL-2 and TROLL-3, that c
Externí odkaz:
https://doaj.org/article/54b1981e95054652a2e282a7299606ef
Autor:
John V. Heymach, William N. William, Diana Bell, Mark J. McArthur, Jeffrey N. Myers, Jing Wang, Xiangjun Tian, Don L. Gibbons, Limo N. Chen, Jared J. Fradette, Hampartsoum B. Barsoumian, Alissa Poteete, Marlese A. Pisegna, Monique Nilsson, Irene Guijarro, Taghreed Hirz, Jose A. Monteiro de Oliveira Novaes
We have previously demonstrated that PD-1 blockade decreased the incidence of high-grade dysplasia in a carcinogen-induced murine model of oral squamous cell carcinoma (OSCC). It remains unknown, however, whether there are additional factors involved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80b501a7ce5502e03c3d3ea9f147e78f
https://doi.org/10.1158/1940-6207.c.6547574.v1
https://doi.org/10.1158/1940-6207.c.6547574.v1
Autor:
John V. Heymach, William N. William, Diana Bell, Mark J. McArthur, Jeffrey N. Myers, Jing Wang, Xiangjun Tian, Don L. Gibbons, Limo N. Chen, Jared J. Fradette, Hampartsoum B. Barsoumian, Alissa Poteete, Marlese A. Pisegna, Monique Nilsson, Irene Guijarro, Taghreed Hirz, Jose A. Monteiro de Oliveira Novaes
Percentage of CD4+CD44hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42578ae452859acd70f62143e2bb7dc1
https://doi.org/10.1158/1940-6207.22534616.v1
https://doi.org/10.1158/1940-6207.22534616.v1
Autor:
John V. Heymach, William N. William, Diana Bell, Mark J. McArthur, Jeffrey N. Myers, Jing Wang, Xiangjun Tian, Don L. Gibbons, Limo N. Chen, Jared J. Fradette, Hampartsoum B. Barsoumian, Alissa Poteete, Marlese A. Pisegna, Monique Nilsson, Irene Guijarro, Taghreed Hirz, Jose A. Monteiro de Oliveira Novaes
Table 1: Pathology classification criteria. Table 2: Flow cytometry antibodies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bef355f22eaae0de6c6c16b9464a09f
https://doi.org/10.1158/1940-6207.22534613.v1
https://doi.org/10.1158/1940-6207.22534613.v1
Autor:
John V. Heymach, John D. Minna, Ralph J. DeBerardinis, Ferdinandos Skoulidis, Varsha Gandhi, Jing Wang, Francesco Parlati, Winter Zhang, Mirna L.M. Rodriguez, Lindsey K. Boroughs, Pei-Hsuan Chen, Pan Tong, Marlese A. Pisegna, Alissa Poteete, Xiao Qu, Piyada Sitthideatphaiboon, Ana Galan-Cobo
In KRAS-mutant lung adenocarcinoma, tumors with LKB1 loss (KL) are highly enriched for concurrent KEAP1 mutations, which activate the KEAP1/NRF2 pathway (KLK). Here, we investigated the biological consequences of these cooccurring alterations and exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be2efb6bf974b8a43395329e688bf871
https://doi.org/10.1158/0008-5472.c.6510938.v1
https://doi.org/10.1158/0008-5472.c.6510938.v1
Autor:
John V. Heymach, John D. Minna, Ralph J. DeBerardinis, Ferdinandos Skoulidis, Varsha Gandhi, Jing Wang, Francesco Parlati, Winter Zhang, Mirna L.M. Rodriguez, Lindsey K. Boroughs, Pei-Hsuan Chen, Pan Tong, Marlese A. Pisegna, Alissa Poteete, Xiao Qu, Piyada Sitthideatphaiboon, Ana Galan-Cobo
Abbreviations used in the manuscript.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2a01bdfa5c985b6326918ded87ce86d
https://doi.org/10.1158/0008-5472.22421474.v1
https://doi.org/10.1158/0008-5472.22421474.v1
Autor:
John V. Heymach, John D. Minna, Ralph J. DeBerardinis, Ferdinandos Skoulidis, Varsha Gandhi, Jing Wang, Francesco Parlati, Winter Zhang, Mirna L.M. Rodriguez, Lindsey K. Boroughs, Pei-Hsuan Chen, Pan Tong, Marlese A. Pisegna, Alissa Poteete, Xiao Qu, Piyada Sitthideatphaiboon, Ana Galan-Cobo
Supplementary bioinformatic analysis and CB-839 effects on in vitro cell proliferation, ROS stress and metabolism.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13da4f81e5c7de81e10d6cf4c6c96569
https://doi.org/10.1158/0008-5472.22421477
https://doi.org/10.1158/0008-5472.22421477
Autor:
Avani A. Deshpande, Ivan Barannikov, Philip R. Quinlan, Marco Napoli, Jurgen Mitsch, Cristian Coarfa, Isabelle Bedrosian, Elsa R. Flores, Xiaobo Li, Kimal Rajapakshe, Preethi H. Gunaratne, Marlese A. Pisegna, Anthony M. Magliocco, Kenneth Y. Tsai, Alastair M. Thompson, Douglas C. Marchion, Hayley D. Ackerman
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
The most frequent genetic alterations across multiple human cancers are mutations in TP53 and the activation of the PI3K/AKT pathway, two events crucial for cancer progression. Mutations in TP53 lead to the inhibition of the tumour and metastasis sup
Autor:
Ana, Galan-Cobo, Piyada, Sitthideatphaiboon, Xiao, Qu, Alissa, Poteete, Marlese A, Pisegna, Pan, Tong, Pei-Hsuan, Chen, Lindsey K, Boroughs, Mirna L M, Rodriguez, Winter, Zhang, Francesco, Parlati, Jing, Wang, Varsha, Gandhi, Ferdinandos, Skoulidis, Ralph J, DeBerardinis, John D, Minna, John V, Heymach
Publikováno v:
Cancer Res
In KRAS-mutant lung adenocarcinoma, tumors with LKB1 loss (KL) are highly enriched for concurrent KEAP1 mutations, which activate the KEAP1/NRF2 pathway (KLK). Here we investigated the biological consequences of these co-occurring alterations and exp