Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Marlene Zuraek"'
Autor:
Maria Vieito, Matteo Simonelli, Filip de Vos, Victor Moreno, Marjolein Geurts, Elena Lorenzi, Marina Macchini, Martin J van den Bent, Gianluca Del Conte, Maja de Jonge, Maria Cruz Martín-Soberón, Barbara Amoroso, Tania Sanchez-Perez, Marlene Zuraek, Bishoy Hanna, Ida Aronchik, Ellen Filvaroff, Henry Chang, Cristina Mendez, Marina Arias Parro, Xin Wei, Zariana Nikolova, Juan Manuel Sepulveda
Publikováno v:
Neuro-Oncology Advances, 4(1):vdac146. Oxford University Press
Scientia
Scientia
Background Standard-of-care treatment for newly diagnosed glioblastoma (ndGBM), consisting of surgery followed by radiotherapy (RT) and temozolomide (TMZ), has improved outcomes compared with RT alone; however, prognosis remains poor. Trotabresib, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f12eaafe59322f3b7697cccec754b55
https://pure.eur.nl/en/publications/8c7f43ea-d16a-4ab8-9cbc-301f4b9a0462
https://pure.eur.nl/en/publications/8c7f43ea-d16a-4ab8-9cbc-301f4b9a0462
Autor:
Victor Moreno, Juan Manuel Sepúlveda, David A Reardon, Ángel Pérez-Núñez, Pedro González León, Bishoy Hanna, Ellen Filvaroff, Ida Aronchik, Henry Chang, Barbara Amoroso, Marlene Zuraek, Tania Sanchez-Perez, Cristina Mendez, Daniel Stephens, Zariana Nikolova, Michael A Vogelbaum
Publikováno v:
Neuro-oncology.
Background The bromodomain and extraterminal protein (BET) inhibitor trotabresib has demonstrated antitumor activity in patients with advanced solid tumors, including high-grade gliomas. CC-90010-GBM-001 (NCT04047303) is a phase I study investigating
Autor:
Maria Vieito, Juan Manuel Sepulveda, Victor Moreno, Filip de Vos, Marjolein Geurts, Elena Lorenzi, Marina Macchini, Martin van den Bent, Gianluca Del Conte, Maria Cruz Martín-Soberón, Petter Brandal, Maria Martinez Garcia, Barbara Amoroso, Tania Sanchez-Perez, Marlene Zuraek, Bishoy Hanna, Ellen Filvaroff, Henry Chang, Marina Arias Parro, Xin Wei, Yu Liu, Zariana Nikolova, Matteo Simonelli
Publikováno v:
Neuro-Oncology. 24:vii75-vii75
Trotabresib, a novel bromodomain and extraterminal protein inhibitor, has demonstrated antitumor activity and blood–brain barrier penetration in patients with high-grade gliomas, and enhanced the antiproliferative effects of temozolomide in preclin
Autor:
B. Hanna, I. Aronchik, T. Sánchez-Pérez, Bernard Doger, Tatiana Hernandez-Guerrero, O. Ferrero, R. Sarmiento, Juan Manuel Sepúlveda, J. De Alvaro, Irene Brana, J. Di Martino, Marlene Zuraek, O. Saavedra, Manisha Lamba, Maria Vieito, E. Filvaroff, Victor Moreno, M. Arias, Zariana Nikolova
Publikováno v:
Scientia
Inhibidor de BET; Limfoma no Hodgkin; Tumors sòlids Inhibidor de BET; Linfoma no Hodgkin; Tumores sólidos BET inhibitor; Non-Hodgkin's lymphoma; Solid tumors Background Bromodomain and extra-terminal (BET) proteins are epigenetic readers that regul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::083e48a69c575d6a62ef3e9b80325312
https://hdl.handle.net/11351/6326
https://hdl.handle.net/11351/6326
Autor:
B. Hanna, Michael A. Vogelbaum, Victor Moreno, Barbara Amoroso, Marlene Zuraek, David A. Reardon, E. Filvaroff, I. Aronchik, T. Sánchez-Pérez, Zariana Nikolova, Juan Manuel Sepúlveda, Cristina Mendez
Publikováno v:
Neuro Oncol
Trotabresib is a potent, reversible oral BETi with antitumor activity in patients with advanced malignancies (Moreno et al. ESMO 2020. Abstract 5270). The CC-90010-GBM-001 study (NCT04047303) enrolled patients with progressive or recurrent astrocytom
Autor:
Cecilia Carpio, Alejandro Martín, Xin Wei, Daniel O. Persky, Charalambos Andreadis, Ying Fei Li, Kristen Hege, Pau Abrisqueta, Michael R. Burgess, Daniel Morillo Giles, Raul Cordoba, Juan-Manuel Sancho, Marlene Zuraek, Scott F. Huntington
Publikováno v:
Blood
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Background: Cluster of differentiation 47 (CD47), a widely expressed cell-surface ligand,is overexpressed in various malignancies and is correlated with worse outcomes in NHL. Interaction of CD47 and signal regulatory protein-α (SIRPα) delivers an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f1a09a313cdead924e3b9321afb3461
https://fundanet.igtp.cat/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=2901
https://fundanet.igtp.cat/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=2901
Autor:
T.C. Hernandez Guerrero, Ana Rita Martins Pinto, R. Sarmiento, Marlene Zuraek, G. Musuraca, B. Hanna, Bernard Doger, J-M. Michot, J. De Alvaro, I. Aronchik, T. Sánchez-Pérez, J.M. Sepulveda Sanchez, C. Carlo Stella, O. Saavedra, Victor Moreno, Irene Brana, Zariana Nikolova, Antoine Italiano, E. Filvaroff, M. Vieito Villar
Publikováno v:
Annals of Oncology. 31:S5
Autor:
Jon M. Greif, Marlene Zuraek, Soheila Korourian, Lisa Bailey, Nandini Kulkarni, V. Suzanne Klimberg, Christopher M. Pezzi
Publikováno v:
Annals of Surgical Oncology. 20:2236-2241
Adenoid cystic carcinoma (ACC) is a rare subtype of breast malignancy. Patients with ACC and infiltrating ductal carcinoma (IDC) reported to the National Cancer Data Base from 1998 to 2008 were reviewed for patient age, ethnicity, tumor size, nodal s
Publikováno v:
Annals of Surgical Oncology. 19:3199-3204
To examine gender-specific differences in breast cancer utilizing the National Cancer Data Base (NCDB).Breast cancer patients entered in the NCDB from 1998 through 2007 were compared by gender for demographics, tumor characteristics, treatment, and o
Autor:
Kristen Hege, Umberto Vitolo, Reda Bouabdallah, Annalisa Chiappella, Michael Pourdehnad, Marlene Zuraek, Zariana Nikolova, Rafael Sarmiento, Pier Luigi Zinzani, Jeanette K. Doorduijn, Vincent Ribrag, Marie José Kersten, Jean-Marie Michot
Publikováno v:
Blood. 128:4199-4199
Background: CC-122, a pleiotropic pathway modifier, modulates the cullin 4 ring E3 ligase complex, which results in recruitment and degradation of Aiolos and Ikaros. This substrate degradation results in cell autonomous anti-lymphoma and immunomodula