Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Marlene Snider"'
Autor:
Sylvia van Drunen Littel-van den Hurk, Sams Mohammad Anowar Sadat, Marlene Snider, Ravendra Garg, Robert Brownlie
Publikováno v:
Vaccine. 35:3466-3473
Bovine viral diarrhea virus (BVDV) is one of the most serious pathogens in cattle. Recently, we developed a novel adjuvant platform (TriAdj) that includes a toll-like receptor 3 agonist, poly (I:C); an innate defense regulatory peptide; and water-sol
Autor:
Robert Brownlie, Suresh K. Tikoo, Kuan Zhang, Soumya Sucharita, Marlene Snider, Tara Donovan, Sylvia van Drunen Littel-van den Hurk
Publikováno v:
Journal of Virology. 93
Bovine herpesvirus 1 (BoHV-1) infects bovine species, causing respiratory infections, genital disorders and abortions. VP8 is the most abundant tegument protein of BoHV-1 and is critical for virus replication in cattle. In this study, the cellular tr
Autor:
Sylvia van Drunen Littel-van den Hurk, Brenden Van Wyk, Marlene Snider, Scott Napper, Erin Scruten
Publikováno v:
Veterinary Microbiology. 195:104-114
As a part of their pathogenic mechanism, many pathogens causing persistent infections, including bovine viral diarrhea virus (BVDV), immunosuppress their hosts, often by limiting the ability to either produce, or respond to, interferon. The objective
Autor:
Jan van den Hurk, Ravendra Garg, Sylvia van Drunen Littel-van den Hurk, Robert Brownlie, Marlene Snider
Publikováno v:
Vaccine. 32:6758-6764
Bovine viral diarrhea virus (BVDV) is still one of the most serious pathogens in cattle, meriting the development of improved vaccines. Recently, we developed a new adjuvant consisting of poly[di(sodium carboxylatoethylphenoxy)]-phosphazene (PCEP), e
Autor:
Marlene Snider, Jan V. van den Hurk, Zoe Lawman, Sylvia van Drunen Littel-van den Hurk, Barry Ellefsen, Donald Wilson, Drew Hannaman
Publikováno v:
Clinical and Vaccine Immunology. 20:166-173
Bovine viral diarrhea virus (BVDV) is a pathogen of major importance in cattle, so there is a need for new effective vaccines. DNA vaccines induce balanced immune responses and are relatively inexpensive and thus promising for both human and veterina
Publikováno v:
Journal of virology. 90(9)
VP8 is a major tegument protein of bovine herpesvirus 1 (BoHV-1) and is essential for viral replication in cattle. The protein undergoes phosphorylation after transcription through cellular casein kinase 2 (CK2) and a viral kinase, US3. In this study
Autor:
Marlene Snider, Lorne A. Babiuk, Natalya L. Vasilenko, Shaunivan Labiuk, Sylvia van Drunen Littel-van den Hurk, Vladislav A. Lobanov
Publikováno v:
Virus Research. 167:56-66
VP8 is the most abundant tegument protein of bovine herpesvirus-1 (BHV-1). In the present study DNA damage binding protein 1 (DDB1) was identified as interacting partner of VP8. MALDI-TOF mass spectroscopy analysis of proteins co-immunoprecipitated w
Autor:
Vladislav A. Lobanov, Zoe Lawman, Sylvia van Drunen Littel-van den Hurk, Lorne A. Babiuk, Marlene Snider, Sheryl L. Maher-Sturgess
Publikováno v:
Journal of Virology. 84:445-458
Tegument protein VP8 encoded by the U L 47 gene of bovine herpesvirus type 1 (BHV-1) is the most abundant constituent of mature virions. In the present report, we describe the characterization of U L 47 gene-deleted BHV-1 in cultured cells and its na
Autor:
Sharmin Afroz, Robert Brownlie, Sylvia van Drunen Littel-van den Hurk, Marlene Snider, Kuan Zhang
Publikováno v:
Journal of virology. 89(8)
The major tegument protein of bovine herpesvirus 1 (BoHV-1), VP8, is essential for virus replication in cattle. VP8 is phosphorylated in vitro by casein kinase 2 (CK2) and BoHV-1 unique short protein 3 (U S 3). In this study, VP8 was found to be phos
Publikováno v:
The Journal of Immunology. 168:1877-1885
Infectious diseases are responsible for a significant number of deaths during the first weeks of life. Some of the salient pathogens include HSV, HIV, hepatitis B virus, group B streptococcus, Haemophilus sp., and Chlamydia sp. The vertical transmiss