Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Marlene Resch"'
Autor:
Elisabeth Gludovacz, Kornelia Schuetzenberger, Marlene Resch, Katharina Tillmann, Karin Petroczi, Markus Schosserer, Sigrid Vondra, Serhii Vakal, Gerald Klanert, Jürgen Pollheimer, Tiina A Salminen, Bernd Jilma, Nicole Borth, Thomas Boehm
Publikováno v:
eLife, Vol 10 (2021)
Background: Excessive plasma histamine concentrations cause symptoms in mast cell activation syndrome, mastocytosis, or anaphylaxis. Anti-histamines are often insufficiently efficacious. Human diamine oxidase (hDAO) can rapidly degrade histamine and
Externí odkaz:
https://doaj.org/article/d7281aa1f5af4be284b2a714515c12fb
Autor:
Elisabeth Gludovacz, Marlene Resch, Kornelia Schuetzenberger, Karin Petroczi, Daniel Maresch, Stefan Hofbauer, Bernd Jilma, Nicole Borth, Thomas Boehm
Publikováno v:
Glycobiology. 32(5)
Elevated plasma and tissues histamine concentrations can cause severe symptoms in mast cell activation syndrome, mastocytosis or anaphylaxis. Endogenous and recombinant human diamine oxidase (rhDAO) can rapidly and completely degrade histamine, and a
Autor:
Tiina A. Salminen, Kornelia Schuetzenberger, Bernd Jilma, Elisabeth Gludovacz, Gerald Klanert, Serhii Vakal, Sigrid Vondra, Karin Petroczi, Katharina Tillmann, Thomas Boehm, Marlene Resch, Jürgen Pollheimer, Markus Schosserer, Nicole Borth
Publikováno v:
eLife
eLife, Vol 10 (2021)
eLife, Vol 10 (2021)
Background:Excessive plasma histamine concentrations cause symptoms in mast cell activation syndrome, mastocytosis, or anaphylaxis. Anti-histamines are often insufficiently efficacious. Human diamine oxidase (hDAO) can rapidly degrade histamine and t
Autor:
Marlene Resch, Sigrid Vondra, Nikolaus Virgolini, Thomas Boehm, Nicole Borth, Karin Petroczi, Elisabeth Gludovacz, Bernd Jilma, Serhii Vakal, Kornelia Schuetzenberger, Tiina A. Salminen, Jürgen Pollheimer, Markus Schosserer, Katharina Tillmann
Publikováno v:
Glycobiology. 31(4)
Human diamine oxidase (hDAO) rapidly inactivates histamine by deamination. No pharmacokinetic data are available to better understand its potential as a new therapeutic modality for diseases with excess local and systemic histamine, like anaphylaxis,
Publikováno v:
Laboratory animals. 53(2)
Intravenous (IV) administration in mice is predominantly performed via the lateral tail veins. The technique requires adequate training before it can be used safely and routinely. A novel anaesthesia induction chamber has been developed to simplify t
Autor:
Sylvia Tippl, Alexander Bauer, Friedrich Scheiflinger, Marlene Resch, Christina Piskernik, Peter Leidenmuehler, Dagmar Verdino, Sabine Knappe, Werner Hoellriegl, Michael Dockal
Publikováno v:
Blood. 122:2353-2353
Treatment of hemophilia A is complicated by development of FVIII neutralizing antibodies, which occurs in ∼30% of patients with severe hemophilia A. Acute bleeds in inhibitor patients can be treated with the available bypassing agents, activated pr
Autor:
Eva-Maria Muchitsch, Werner Hoellriegl, Alexandra Schiviz, Hans Peter Schwarz, Marlene Resch, Hanspeter Rottensteiner, Elisa Farnleitner, Friedrich Scheiflinger
Publikováno v:
Blood. 120:2216-2216
Abstract 2216 Baxter is currently developing a recombinant ADAMTS13 (rADAMTS13, a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13) product for potential prophylaxis and treatment of thrombotic thrombocytopenic purpura
Autor:
Alexandra Schiviz, Marlene Resch, Hartmut J. Ehrlich, Eva-Maria Muchitsch, John-Philip Lawo, Bettina Bischetsrieder, Friedrich Scheiflinger, Werner Hoellriegl, Peter Leidenmuehler, Hans Peter Schwarz
Publikováno v:
Blood. 116:4659-4659
Abstract 4659 Baxter has developed a recombinant FVIIa (rFVIIa) product for the treatment of patients with hemophilia A and hemophilia B with inhibitors. The aim of the presented preclinical studies was to evaluate the efficacy of Baxter's rFVIIa. Fo