Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Marlene F. Cox"'
Autor:
John E. Brown, Howard Kendrick, Yaman Gökçek, Pamela Pollet, Colin W. Wright, Roger M. Phillips, Anthony G. Breen, Marlene F. Cox, Jonathan Addae-Kyereme, Simon L. Croft
Publikováno v:
Journal of Medicinal Chemistry. 44:3187-3194
The indoloquinoline alkaloid cryptolepine 1 has potent in vitro antiplasmodial activity, but it is also a DNA intercalator with cytotoxic properties. We have shown that the antiplasmodial mechanism of 1 is likely to be due, at least in part, to a chl
Publikováno v:
Journal of Natural Products. 52:75-80