Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Marlene Darfler"'
Autor:
Daniel V T Catenacci, Wei-Li Liao, Sheeno Thyparambil, Les Henderson, Peng Xu, Lei Zhao, Brittany Rambo, John Hart, Shu-Yuan Xiao, Kathleen Bengali, Jamar Uzzell, Marlene Darfler, David B Krizman, Fabiola Cecchi, Donald P Bottaro, Theodore Karrison, Timothy D Veenstra, Todd Hembrough, Jon Burrows
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e100586 (2014)
Overexpression of Met tyrosine kinase receptor is associated with poor prognosis. Overexpression, and particularly MET amplification, are predictive of response to Met-specific therapy in preclinical models. Immunohistochemistry (IHC) of formalin-fix
Externí odkaz:
https://doaj.org/article/63bb698729444933a2050156f8451ab8
Autor:
Daniel V.T. Catenacci, Les Henderson, David Krisman, Shu-Yuan Xiao, Todd Hembrough, Lei Zhao, Sheeno Thyparambil, Wei-Li Liao, Kathleen Bengali, Emma Whitcomb, Jamar Uzzell, Emily O'Day, Peng Xu, Adele Blackler, John Hart, Sang Mee Lee, Yung-Jue Bang, Marlene Darfler, Jon Burrows, Fabiola Cecchi
Publikováno v:
Gastric Cancer. 19:1066-1079
Trastuzumab has shown a survival benefit in cases of Her2-positive gastroesophageal cancer (GEC). Immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH) currently determine eligibility for trastuzumab-based therapy. However, these l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fbd172279a97844ddf028dc22990161
https://doi.org/10.1007/s10120-015-0566-0
https://doi.org/10.1007/s10120-015-0566-0
Autor:
Albert J. Kovatich, Nicholas W. Bateman, Marlene Darfler, Jeffrey A. Hooke, Mai Sun, David B. Krizman, Brian L. Hood, Rohit Bhargava, Thomas P. Conrads
Publikováno v:
Journal of Proteome Research. 10:1323-1332
The heterogeneity of breast cancer requires the discovery of more incisive molecular tools that better define disease progression and prognosis. Proteomic analysis of homogeneous tumor cell populations derived by laser microdissection from formalin-f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f06c0045e8e5ca67261291fb4777c518
https://doi.org/10.1021/pr101073s
https://doi.org/10.1021/pr101073s
Publikováno v:
The Open Proteomics Journal. 1:40-45
Human immunodeficiency virus (HIV) infection is associated with dysplastic changes in oral human papilloma virus (HPV) lesions, suggesting changes in keratinocytes. In the present study, we seek to identify proteomic changes in oral HPV lesions betwe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51cf7910f833deda8a5dded89ed2b081
https://doi.org/10.2174/1875039700801010040
https://doi.org/10.2174/1875039700801010040
Autor:
Peng Xu, Yung-Jue Bang, Adele Blackler, Emma Whitcomb, Shu-Yuan Xiao, Jamar Uzzell, John Hart, Kathleen Bengali, Fabiola Cecchi, Wei-Li Liao, Emily O'Day, Daniel V.T. Catenacci, Sheeno Thyparambil, David Krisman, Marlene Darfler, Todd Hembrough, Lei Zhao, Jon Burrows, Les Henderson, Sang Mee Lee
Background: Trastuzumab showed survival benefit for Her2-positive gastroesophageal cancers (GEC). Immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH) currently determine eligibility for trastuzumab-based therapy. However, both as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ad9f3afd0ac82c630a28a0c8c252584
Autor:
Brian L. Hood, Thomas P. Conrads, Bradley R. Ringeisen, Timothy D. Veenstra, Bungo Furusato, David A. Lucas, David B. Krizman, Thomas G. Guiel, Marlene Darfler, Isabell A. Sesterhenn
Publikováno v:
Molecular & Cellular Proteomics. 4:1741-1753
Proteomic analysis of formalin-fixed paraffin-embedded (FFPE) tissue would enable retrospective biomarker investigations of this vast archive of pathologically characterized clinical samples that exist worldwide. These FFPE tissues are, however, refr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7182aec0c2fa49ed17d891fce916a5b
https://doi.org/10.1074/mcp.m500102-mcp200
https://doi.org/10.1074/mcp.m500102-mcp200
Autor:
H. D. Young, D. B. Krizman, Dana D. Dlott, Bradley R. Ringeisen, Jason A. Barron, Marlene Darfler
Publikováno v:
PROTEOMICS. 5:4138-4144
Current proteomics experiments rely upon printing techniques such as ink jet, pin, or quill arrayers that were developed for the creation of cDNA microarrays. These techniques often do not meet the requirements needed for successful spotting of prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67ce07ae7e21f35b44b230adb40a55d0
https://doi.org/10.1002/pmic.200401294
https://doi.org/10.1002/pmic.200401294
Autor:
Mike Emmert-Buck, Sarit Schwartz, Shankar Sellappan, Chao Gong, Todd Hembrough, Marlene Darfler, Fabiola Cecchi, Steven W. Mamus, Kerry Scott
Publikováno v:
Cancer Research. 77:209-209
Introduction: Targeted therapies successful in treating primary tumors are often ineffective against corresponding metastatic lesions. Tumors and their bone metastases are biologically distinct, as reflected by discordant biomarker status. Decalcific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db0a3305390b2ce0eda799287a877e83
https://doi.org/10.1158/1538-7445.am2017-209
https://doi.org/10.1158/1538-7445.am2017-209
Autor:
Shu-Yuan Xiao, Brittany Rambo, Fabiola Cecchi, Jon Burrows, Daniel V.T. Catenacci, Wei-Li Liao, Lei Zhao, David B. Krizman, Kathleen Bengali, Peng Xu, Theodore Karrison, Jamar Uzzell, Marlene Darfler, Les Henderson, Todd Hembrough, Sheeno Thyparambil, John Hart, Donald P. Bottaro, Timothy D. Veenstra
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e100586 (2014)
PLoS ONE
PLoS ONE
Background Overexpression of Met tyrosine kinase receptor is associated with poor prognosis. Overexpression, and particularly MET amplification, are predictive of response to Met-specific therapy in preclinical models. Immunohistochemistry (IHC) of f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79d71786fbe08a62b2dee0a68f0cdd40
http://europepmc.org/articles/PMC4077664?pdf=render
http://europepmc.org/articles/PMC4077664?pdf=render
Autor:
Jon Burrows, Stephen M. Hewitt, Marlene Darfler, Todd Hembrough, Richard A. Bender, Wei-Li Liao, David B. Krizman, Joseph Abdo, Kathleen Bengali, Sheeno Thyparambil
Publikováno v:
The Journal of molecular diagnostics : JMD. 15(4)
One of the critical gaps in the clinical diagnostic space is the lack of quantitative proteomic methods for use on formalin-fixed, paraffin-embedded (FFPE) tissue. Herein, we describe the development of a quantitative, multiplexed, mass spectrometry-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::472c90c757115f72520677b7e9e04f5a
https://pubmed.ncbi.nlm.nih.gov/23672976
https://pubmed.ncbi.nlm.nih.gov/23672976