A multicenter study of ketamine effects on functional connectivity: Large scale network relationships, hubs and symptom mechanisms

Autor: Leah M. Fleming, Daniel C. Javitt, Cameron S. Carter, Joshua T. Kantrowitz, Ragy R. Girgis, Lawrence S. Kegeles, John D. Ragland, Richard J. Maddock, Tyler A. Lesh, Costin Tanase, James Robinson, William Z. Potter, Marlene Carlson, Melanie M. Wall, Tse-Hwei Choo, Jack Grinband, Jeffrey Lieberman, John H. Krystal, Philip R. Corlett

Publikováno v: NeuroImage: Clinical, Vol 22, Iss , Pp - (2019)

Ketamine is an uncompetitive N-methyl-d-aspartate (NMDA) glutamate receptor antagonist. It induces effects in healthy individuals that mimic symptoms associated with schizophrenia. We sought to root these experiences in altered brain function, specif

Externí odkaz: https://doaj.org/article/11febe31fb8443d1b081e08d479a69f3

Dose-Dependent Augmentation of Neuroplasticity-Based Auditory Learning in Schizophrenia: A Double-Blind, Placebo-Controlled, Randomized, Target Engagement Clinical Trial of the NMDA Glutamate Receptor Agonist d-serine

Autor: Pejman Sehatpour, Dan V. Iosifescu, Heloise M. De Baun, Constance Shope, Megan R. Mayer, James Gangwisch, Elisa Dias, Tarek Sobeih, Tse-Hwei Choo, Melanie M. Wall, Alice Medalia, Alice M. Saperstein, Lawrence S. Kegeles, Ragy R. Girgis, Marlene Carlson, Joshua T. Kantrowitz

Publikováno v: Biological Psychiatry.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e193f22e90932e567aedea55e5730bde
https://doi.org/10.1016/j.biopsych.2023.01.015

Illness Phase as a Key Assessment and Intervention Window for Psychosis

Autor: Christian G. Kohler, Daniel H. Wolf, Anissa Abi-Dargham, Alan Anticevic, Youngsun T. Cho, Clara Fonteneau, Roberto Gil, Ragy R. Girgis, David L. Gray, Jack Grinband, Jonathan A. Javitch, Joshua T. Kantrowitz, John H. Krystal, Jeffrey A. Lieberman, John D. Murray, Mohini Ranganathan, Nicole Santamauro, Jared X. Van Snellenberg, Zailyn Tamayo, Ruben C. Gur, Raquel E. Gur, Monica E. Calkins, Deepak D'Souza, Vinod Srihari, Ralitza Gueorguieva, Prashant Patel, Kimberlee Forselius-Bielen, Jing Lu, Audrey Butler, Geena Fram, Yvette Afriyie-Agyemang, Alexandria Selloni, Laura Cadavid, Sandra Gomez-Luna, Aarti Gupta, Rajiv Radhakrishnan, Ali Rashid, Ryan Aker, Philisha Abrahim, Anahita Bassir Nia, Toral Surti, Lawrence S. Kegeles, Marlene Carlson, Terry Goldberg, James Gangwisch, Erinne Benedict, Preetika Govil, Stephanie Brazis, Megan Mayer, Nathalie de la Garrigue, Natalka Fallon, Topaz Baumvoll, Sameera Abeykoon, Greg Perlman, Kelly Bobchin, Mark Elliott, Lyndsay Schmidt, Sage Rush, Allison Port, Zac Heffernan, Nina Laney, Jenna Kantor, Thomas Hohing

Publikováno v: Biological Psychiatry Global Open Science.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::809975a60bd69a74bfe23a4ce78bf15e
https://doi.org/10.1016/j.bpsgos.2022.05.009

Grant Report on d-Serine Augmentation of Neuroplasticity-Based Auditory Learning in Schizophrenia

Autor: Natalie, de la Garrigue, Juliana, Glasser, Pejman, Sehatpour, Dan V, Iosifescu, Elisa, Dias, Marlene, Carlson, Constance, Shope, Tarek, Sobeih, Tse-Hwei, Choo, Melanie M, Wall, Lawrence S, Kegeles, James, Gangwisch, Megan, Mayer, Stephanie, Brazis, Heloise M, De Baun, Stephanie, Wolfer, Dalton, Bermudez, Molly, Arnold, Danielle, Rette, Amir M, Meftah, Melissa, Conant, Jeffrey A, Lieberman, Joshua T, Kantrowitz

Publikováno v: Journal of psychiatry and brain science

We report on the rationale and design of an ongoing NIMH sponsored R61-R33 project in schizophrenia/schizoaffective disorder. This project studies augmenting the efficacy of auditory neuroplasticity cognitive remediation (AudRem) with d-serine, an N-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d3c0423ea209b502fd8b428cc0b1489b
https://pubmed.ncbi.nlm.nih.gov/32856005

A multicenter study of ketamine effects on functional connectivity: Large scale network relationships, hubs and symptom mechanisms

Autor: Marlene Carlson, Jack Grinband, Daniel C. Javitt, Leah Fleming, Jeffrey A. Lieberman, Melanie M. Wall, Richard J. Maddock, John H. Krystal, Tse Hwei Choo, Tyler A. Lesh, James Robinson, Costin Tanase, John D Ragland, Ragy R. Girgis, Lawrence S. Kegeles, Joshua T. Kantrowitz, William Z. Potter, Philip R. Corlett, Cameron S. Carter

Publikováno v: NeuroImage: Clinical, Vol 22, Iss, Pp-(2019)
Fleming, Leah M; Javitt, Daniel C; Carter, Cameron S; Kantrowitz, Joshua T; Girgis, Ragy R; Kegeles, Lawrence S; et al.(2019). A multicenter study of ketamine effects on functional connectivity: Large scale network relationships, hubs and symptom mechanisms. NeuroImage: Clinical, 22, 101739-101739. doi: 10.1016/j.nicl.2019.101739. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/72t6646j
NeuroImage : Clinical

Ketamine is an uncompetitive N-methyl-d-aspartate (NMDA) glutamate receptor antagonist. It induces effects in healthy individuals that mimic symptoms associated with schizophrenia. We sought to root these experiences in altered brain function, specif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::129e54a1eb6b31ab61cefac81ff6924f
https://escholarship.org/uc/item/72t6646j