Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Marlene A. Jacobson"'
Autor:
Robert A. Brown, Antanina Voit, Manasa P. Srikanth, Julia A. Thayer, Tami J. Kingsbury, Marlene A. Jacobson, Marta M. Lipinski, Ricardo A. Feldman, Ola Awad
Publikováno v:
Disease Models & Mechanisms, Vol 12, Iss 10 (2019)
Bi-allelic GBA1 mutations cause Gaucher's disease (GD), the most common lysosomal storage disorder. Neuronopathic manifestations in GD include neurodegeneration, which can be severe and rapidly progressive. GBA1 mutations are also the most frequent g
Externí odkaz:
https://doaj.org/article/071ad8f2001a470988d9369dd1d74923
Autor:
Mahiya Habib, Melissa B. Korman, Lital Aliasi-Sinai, Sophia den Otter-Moore, Lesley Gotlib Conn, Alva Murray, Marlene Carno Jacobson, Danny Enepekides, Kevin Higgins, Janet Ellis
Publikováno v:
Canadian Oncology Nursing Journal, Vol 33, Iss 1, Pp 74-86 (2023)
Objectives: To address the knowledge gap in the practice of compassionate healthcare by elucidating patient perspectives on compassion, empathy, and sympathy.Methods: Semi-structured telephone interviews were conducted at two time points with patient
Externí odkaz:
https://doaj.org/article/63acd78faf054c7b910dad31af59da2a
Autor:
Mahiya Habib, Melissa B. Korman, Lital Aliasi-Sinai, Sophia den Otter-Moore, Lesley Gotlib Conn, Alva Murray, Marlene Carno Jacobson, Danny Enepekides, Kevin Higgins, Janet Ellis
Publikováno v:
Canadian Oncology Nursing Journal, Vol 33, Iss 1, Pp 87-100 (2023)
Objectifs : Améliorer les connaissances sur la pratique des soins compatissants en mettant en lumière le point de vue des patients sur la compassion, l’empathie et la sympathie.Méthodes : Des entretiens téléphoniques semi-structurés ont été
Externí odkaz:
https://doaj.org/article/de2b8a1c1946462a9a0cf4576d4697e3
Autor:
Rodrigo B. Andrade, Miseon Lee, Christiana N. Teijaro, Bettina A. Buttaro, Marlene A. Jacobson, Samer S. Daher, Xiao Jin, Steven E. Wheeler
Publikováno v:
ChemMedChem
There is an urgent need for new antibiotics to mitigate the existential threat posed by antibiotic resistance. Within the ketolide class, solithromycin has emerged as one of the most promising candidates for further development. Crystallographic stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7928f0af5666f0e24e227ef8268f10a6
https://europepmc.org/articles/PMC8571068/
https://europepmc.org/articles/PMC8571068/
Publikováno v:
Journal of General Physiology. 153
Large-conductance Ca2+-activated K+ (BK) channels control a range of physiological functions, and their dysfunction is linked to human disease. We have found that the widely used drug loperamide (LOP) can inhibit activity of BK channels composed of e
Publikováno v:
Successful Drug Discovery
Publikováno v:
ACS Chemical Neuroscience. 10:3662-3670
Cone photoreceptor cyclic-nucleotide gated channels (CNG) are tetrameric proteins composed of subunits from CNGA3 and CNGB3. These channels transduce light information into electrical signals carried by both Na+ and Ca2+ ions. More than 100 mutations
Autor:
John Gordon, Rogelio Martinez, Dennis J. Colussi, Edward Melenski, Marlene A. Jacobson, Rong Fan, Yuxiao Liu, Wayne E. Childers, Magid Abou-Gharbia
Publikováno v:
Bioorg Med Chem Lett
Gaucher disease (GD) results from inherited mutations in the lysosomal enzyme β-glucocerobrosidase (GCase). Currently available treatment options for Type 1 GD are not efficacious for treating neuronopathic Type 2 and 3 GD due to their inability to
Autor:
Julia A. Thayer, Marlene A. Jacobson, Marta M. Lipinski, Ola Awad, Robert A. Brown, Antanina Voit, Ricardo A. Feldman, Manasa P Srikanth, Tami J. Kingsbury
Publikováno v:
Disease Models & Mechanisms, Vol 12, Iss 10 (2019)
Disease Models & Mechanisms
Disease Models & Mechanisms
Bi-allelic GBA1 mutations cause Gaucher's disease (GD), the most common lysosomal storage disorder. Neuronopathic manifestations in GD include neurodegeneration, which can be severe and rapidly progressive. GBA1 mutations are also the most frequent g
Autor:
Marlene Carno Jacobson
Publikováno v:
Current Opinion in Supportive & Palliative Care. 12:65-73
The head and neck cancer (HNC) survivorship experience is unique among cancer populations. This review seeks to explore the HNC survivor experience associated with altered upper aerodigestive tract (UADT) function using principles of survivorship.HNC