Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Marlene, Oeffinger"'
Autor:
Pudchalaluck Panichnantakul, Lisbeth C. Aguilar, Evan Daynard, Mackenzie Guest, Colten Peters, Jackie Vogel, Marlene Oeffinger
Publikováno v:
Cell Reports, Vol 43, Iss 9, Pp 114738- (2024)
Summary: The highly repetitive and transcriptionally active ribosomal DNA (rDNA) genes are exceedingly susceptible to genotoxic stress. Induction of DNA double-strand breaks (DSBs) in rDNA repeats is associated with ataxia-telangiectasia-mutated (ATM
Externí odkaz:
https://doaj.org/article/ac9d1089b05a4acc9376bfd75ca23e5d
Autor:
Marlene Oeffinger
Publikováno v:
RNA Biology, Vol 20, Iss 1, Pp 307-310 (2023)
Externí odkaz:
https://doaj.org/article/17071618aa8543fe9ca050a14c1bc490
Autor:
Christian Trahan, Marlene Oeffinger
Publikováno v:
RNA Biology, Vol 20, Iss 1, Pp 177-185 (2023)
For over 40 years, ribosomes were considered monolithic machines that translate the genetic code indiscriminately. However, over the past two decades, there have been a growing number of studies that suggest ribosomes to have a degree of compositiona
Externí odkaz:
https://doaj.org/article/a57b8ee107be45a59b1b692a59be128c
Autor:
Camille Laliberté, Bianca Bossé, Véronique Bourdeau, Luis I. Prieto, Genève Perron-Deshaies, Nhung Vuong-Robillard, Sebastian Igelmann, Lisbeth Carolina Aguilar, Marlene Oeffinger, Darren J. Baker, Luc DesGroseillers, Gerardo Ferbeyre
Publikováno v:
Biomedicines, Vol 12, Iss 5, p 1089 (2024)
Senescent cells, which accumulate with age, exhibit a pro-inflammatory senescence-associated secretory phenotype (SASP) that includes the secretion of cytokines, lipids, and extracellular vesicles (EVs). Here, we established an in vitro model of sene
Externí odkaz:
https://doaj.org/article/f5e4307220324bb7a2aa874149e20fc2
Publikováno v:
STAR Protocols, Vol 4, Iss 3, Pp 102359- (2023)
Summary: Two isoforms of the nuclear pore complex (NPC) have been identified in the yeast S. cerevisiae, which coexist at the periphery of the nucleus and differ by the presence or absence of a nuclear basket. Here, we present a protocol to isolate t
Externí odkaz:
https://doaj.org/article/efcaec0098ee4d748f13b1fe59c5a6e8
Autor:
Lidice González, Daniel Kolbin, Christian Trahan, Célia Jeronimo, François Robert, Marlene Oeffinger, Kerry Bloom, Stephen W. Michnick
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Partitioning of active gene loci to the nuclear envelope (NE) is a mechanism by which organisms increase the speed of adaptation and metabolic robustness to fluctuating resources in the environment. In the yeast Saccharomyces cerevisiae, ada
Externí odkaz:
https://doaj.org/article/b9f6de99cf354420860501f8caeb450d
Autor:
Marlene Oeffinger
Publikováno v:
RNA Biology, Vol 20, Iss 1, Pp 306-306 (2023)
Externí odkaz:
https://doaj.org/article/d114fce2ddbb496c87c0580f99c1e78a
Autor:
Anne Helness, Jennifer Fraszczak, Charles Joly-Beauparlant, Halil Bagci, Christian Trahan, Kaifee Arman, Peiman Shooshtarizadeh, Riyan Chen, Marina Ayoub, Jean-François Côté, Marlene Oeffinger, Arnaud Droit, Tarik Möröy
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
Helness et al. show that GFI1/CHD4 complexes critically regulate chromatin accessibility and histone modifications to regulate target genes affecting diverse cellular processes in neutrophils. Their results provide further insight into the molecular
Externí odkaz:
https://doaj.org/article/f4208fa66ce144baa1f83bed6e3a7a19
Autor:
Lidice González, Daniel Kolbin, Christian Trahan, Célia Jeronimo, François Robert, Marlene Oeffinger, Kerry Bloom, Stephen W. Michnick
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/c7da72d7274a41729449be7417a06dce
Autor:
Anne Helness, Jennifer Fraszczak, Charles Joly-Beauparlant, Halil Bagci, Christian Trahan, Kaifee Arman, Peiman Shooshtarizadeh, Riyan Chen, Marina Ayoub, Jean-François Côté, Marlene Oeffinger, Arnaud Droit, Tarik Möröy
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/0005a06cdadb487d9d99f9e5fdde562e