Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Marlen Hesse"'
Autor:
Christoph Arenz, Marlen Hesse
Publikováno v:
ChemBioChem. 17:304-307
Micro RNA (miRNA) research has evolved into an essential part of investigating gene regulation in which deregulation of numerous miRNAs is associated with various cellular dysfunction and diseases. Here, we describe a rapid and homogenous assay for A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3ca8fd497950d8ceba71469423ca8c6
https://doi.org/10.1002/cbic.201500537
https://doi.org/10.1002/cbic.201500537
Autor:
Marlen Hesse, Christoph Arenz
Publikováno v:
Expert opinion on therapeutic patents. 24(11)
Parkinson's disease (PD) requires novel means for early-stage recognition, enabling early therapeutic approaches. Since microRNAs (miRNAs) are important components of the gene regulatory networks in neurodegenerative diseases, there is huge effort to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aecdc65f696a81049b1bff4d183d3114
https://pubmed.ncbi.nlm.nih.gov/25307171
https://pubmed.ncbi.nlm.nih.gov/25307171
Autor:
Marlen, Hesse, Christoph, Arenz
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1095
Numerous studies describe alterations in the levels of specific microRNAs (miRNAs) that are associated with human pathologies. Some of these alterations may give rise to the development of novel diagnostic tools, while certain miRNAs additionally cou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c4be9550edb49704979c45067cd7af1b
https://pubmed.ncbi.nlm.nih.gov/24166300
https://pubmed.ncbi.nlm.nih.gov/24166300
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1095
Assaying Dicer-mediated miRNA maturation is a valuable tool not only for validating miRNA maturation itself but also for testing Dicer activity in cell lysate and for screening small molecules inhibiting miRNA maturation in a high-throughput format.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::58dadf4f248dd8a59ce69fc160b5f78a
https://pubmed.ncbi.nlm.nih.gov/24166305
https://pubmed.ncbi.nlm.nih.gov/24166305
Publikováno v:
Methods in Molecular Biology ISBN: 9781627037020
Assaying Dicer-mediated miRNA maturation is a valuable tool not only for validating miRNA maturation itself but also for testing Dicer activity in cell lysate and for screening small molecules inhibiting miRNA maturation in a high-throughput format.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27406f64337152430c42bbccf35dafca
https://doi.org/10.1007/978-1-62703-703-7_7
https://doi.org/10.1007/978-1-62703-703-7_7
Autor:
Marlen Hesse, Christoph Arenz
Publikováno v:
Methods in Molecular Biology ISBN: 9781627037020
Numerous studies describe alterations in the levels of specific microRNAs (miRNAs) that are associated with human pathologies. Some of these alterations may give rise to the development of novel diagnostic tools, while certain miRNAs additionally cou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0065c34d2371ee7118237bf0d8ebe79a
https://doi.org/10.1007/978-1-62703-703-7_2
https://doi.org/10.1007/978-1-62703-703-7_2
Publikováno v:
Chemical communications (Cambridge, England). 49(30)
The growing interest in single-molecule analysis of RNA calls for programmable enzymatic labeling strategies beyond the horizon of solid-phase synthesized RNAs. Herein we describe an easy and versatile chemo-enzymatic approach to label RNA at its ter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b71c7332b587ae9062c6760a9bb4f11
https://pubmed.ncbi.nlm.nih.gov/23476924
https://pubmed.ncbi.nlm.nih.gov/23476924
Autor:
Sandra Oster, Wladimir Balanzew, Khaled Radad, Marlen Hesse, Heinz Reichmann, Dieter Scheller, Gabriele Gille
Publikováno v:
European journal of pharmacology. 724
In Parkinson disease the degeneration of dopaminergic neurones is believed to lead to a disinhibition of the subthalamic nucleus thus increasing the firing rate of the glutamatergic excitatory projections to the substantia nigra. In consequence, exce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7af1f91f252cff216ff8754b4f7bf5ea
https://pubmed.ncbi.nlm.nih.gov/24365490
https://pubmed.ncbi.nlm.nih.gov/24365490
Autor:
Ana I. Rojo, Antonio Cuadrado, Marlen Hesse, Agnieszka Jazwa, Nadia G. Innamorato, Javier Fernández-Ruiz
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
Biblos-e Archivo. Repositorio Institucional de la UAM
Current therapies for motor symptoms of Parkinson's disease (PD) are based on dopamine replacement. However, the disease progression remains unaffected, because of continuous dopaminergic neuron loss. Since oxidative stress is actively involved in ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74da923da8ce2d2e6634cb8317363531
https://doi.org/10.1089/ars.2010.3731
https://doi.org/10.1089/ars.2010.3731
Autor:
Agnieszka Jazwa, Ana I. Rojo, Nadia G. Innamorato, Marlen Hesse, Javier Fernández-Ruiz, Antonio Cuadrado
Publikováno v:
Antioxidants & Redox Signaling; Jun2011, Vol. 14 Issue 12, p2347-2360, 14p