Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Marlen Haderlein"'
Autor:
Marlen Haderlein, Jens von der Grün, Panagiotis Balermpas, Claus Rödel, Matthias G. Hautmann, Felix Steger, Christopher Bohr, Thomas Hehr, Carmen Stromberger, Volker Budach, Markus Schymalla, Rita Engenhart-Cabillic, Lukas Kocik, Hans Geinitz, Ursula Nestle, Gunter Klautke, Claudia Scherl, Christine Gall, Benjamin Frey, Philipp Schubert, Sabine Semrau, Oliver Ott, Marco Kesting, Heinrich Iro, Sarina K. Mueller, Rainer Fietkau
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundCurrent standard treatment concepts in head and neck squamous cell carcinoma (HNSCC) are based on former studies using 2D and 3D treatment plans. However, modern radiation techniques allow for a more precise and individual dose application.
Externí odkaz:
https://doaj.org/article/246b75ccd09e4ee1b097d2a041e4c169
Autor:
Leah-Sophie Winkler, Marlen Haderlein, Sabine Semrau, Florian Putz, Daniel Höfler, Sarina K. Müller, Heinrich Iro, Marco Kesting, Rainer Fietkau, Philipp Schubert
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
PurposeTreatment of patients with cancer of the head and neck region is in focus in a multitude of studies. Of these patients, one patient group, those aged 76 and more, is mostly underrepresented despite requiring thorough and well-reasoned treatmen
Externí odkaz:
https://doaj.org/article/85aac84226524b96a44e00314dbb6f4f
Autor:
Yixing Huang, Ahmed Gomaa, Sabine Semrau, Marlen Haderlein, Sebastian Lettmaier, Thomas Weissmann, Johanna Grigo, Hassen Ben Tkhayat, Benjamin Frey, Udo Gaipl, Luitpold Distel, Andreas Maier, Rainer Fietkau, Christoph Bert, Florian Putz
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
PurposeThe potential of large language models in medicine for education and decision-making purposes has been demonstrated as they have achieved decent scores on medical exams such as the United States Medical Licensing Exam (USMLE) and the MedQA exa
Externí odkaz:
https://doaj.org/article/8687ab256d584ad782853d71a787129e
Autor:
Adrian Holler, Iwona Cicha, Markus Eckstein, Marlen Haderlein, Marina Pöttler, Anja Rappl, Heinrich Iro, Christoph Alexiou
Publikováno v:
Cancer Medicine, Vol 11, Iss 24, Pp 4743-4755 (2022)
Abstract Background Extramedullary plasmacytoma (EMP) is a solitary tumor consisting of neoplastic plasma cells, with very little to no bone marrow involvement. EMPs are usually located in the head and neck region, but can also occur along the digest
Externí odkaz:
https://doaj.org/article/24f55930fe8d47d1a66ae26100b98e3e
Autor:
Luisa Maria Griewing, Claudia Schweizer, Philipp Schubert, Sandra Rutzner, Markus Eckstein, Benjamin Frey, Marlen Haderlein, Thomas Weissmann, Sabine Semrau, Antoniu-Oreste Gostian, Sarina K. Müller, Maximilian Traxdorf, Heinrich Iro, Jian-Guo Zhou, Udo S. Gaipl, Rainer Fietkau, Markus Hecht
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-10 (2021)
Abstract Background Immune checkpoint inhibitors (ICI) have become standard treatment in different tumor entities. However, safe treatment with ICI targeting the PD-1/PD-L1 axis requires early detection of immune-related adverse events (irAE). There
Externí odkaz:
https://doaj.org/article/588a19908b4c4c22ab7e82c0c6069723
Autor:
Thomas Weissmann, Daniel Höfler, Markus Hecht, Sabine Semrau, Marlen Haderlein, Irina Filimonova, Benjamin Frey, Christoph Bert, Sebastian Lettmaier, Konstantinos Mantsopoulos, Heinrich Iro, Rainer Fietkau, Florian Putz
Publikováno v:
Radiation Oncology, Vol 16, Iss 1, Pp 1-10 (2021)
Abstract Background There is a large lack of evidence for optimal treatment in oligometastatic head and neck cancer and it is especially unclear which patients benefit from radical local treatment of all tumour sites. Methods 40 patients with newly d
Externí odkaz:
https://doaj.org/article/9c6bedc4b6ed4478a4d62c8c68a04e2a
Autor:
Sören Schnellhardt, Johannes Hirneth, Maike Büttner-Herold, Christoph Daniel, Marlen Haderlein, Arndt Hartmann, Rainer Fietkau, Luitpold Distel
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Tumour-infiltrating FoxP3+ regulatory T cells have been identified as both positive and negative prognostic factors in colorectal cancer (CRC) and rectal cancer (RC). In this study we investigated whether immune phenotypes, defined by CD8+ cytotoxic
Externí odkaz:
https://doaj.org/article/160b89a80530479caad81ca805bbe9ce
Autor:
Theresa Mayo, Marlen Haderlein, Barbara Schuster, Anna Wiesmüller, Christian Hummel, Maximilian Bachl, Manfred Schmidt, Rainer Fietkau, Luitpold Distel
Publikováno v:
Radiation Oncology, Vol 15, Iss 1, Pp 1-9 (2019)
Abstract Background Individual radiosensitivity is influencing the outcome of radiation therapy. A general ex vivo testing is very work-intensive. It is of interest to see if a significant prediction concerning the sensitivity can be made by in vivo
Externí odkaz:
https://doaj.org/article/c6c067ce19fa492fa7117b81e75fbea5
Autor:
Marlen Haderlein, Claudia Scherl, Sabine Semrau, Sebastian Lettmaier, Markus Hecht, Florian Putz, Heinrich Iro, Abbas Agaimy, Rainer Fietkau
Publikováno v:
Radiation Oncology, Vol 14, Iss 1, Pp 1-10 (2019)
Abstract Background The aim was to evaluate the outcome, especially locoregional control of patients with locally advanced salivary gland carcinoma (SGC) with perineural spread (Pn1) and/or positive resection margins (R1/2) after postoperative photon
Externí odkaz:
https://doaj.org/article/749adbbb1e114a9bacab53d8f22b7f9e
Autor:
Florian Haller, Matthias Bieg, Rainer Will, Cindy Körner, Dieter Weichenhan, Alexander Bott, Naveed Ishaque, Pavlo Lutsik, Evgeny A. Moskalev, Sarina K. Mueller, Marion Bähr, Angelika Woerner, Birgit Kaiser, Claudia Scherl, Marlen Haderlein, Kortine Kleinheinz, Rainer Fietkau, Heinrich Iro, Roland Eils, Arndt Hartmann, Christoph Plass, Stefan Wiemann, Abbas Agaimy
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Acinic cell carcinoma (AciCC) is a rare salivary gland carcinoma that is poorly understood. Here the authors perform genomic, transcriptomic and epigenomic profiling of AciCC and find highly recurrent and specific rearrangements [t(4;9)(q13;q31)], wh
Externí odkaz:
https://doaj.org/article/727b2361a8284964b7ca75f696b31bab