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A fungal substrate mimicking molecule suppresses plant immunity via an inter-kingdom conserved motif
Autor:
Johana C. Misas Villamil, André N. Mueller, Fatih Demir, Ute Meyer, Bilal Ökmen, Jan Schulze Hüynck, Marlen Breuer, Helen Dauben, Joe Win, Pitter F. Huesgen, Gunther Doehlemann
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Pit2 is a secreted Ustilago maydis effector that contributes to corn smut disease by inhibiting papain-like cysteine proteases (PLCPs) in maize. Here Misas Villamil et al. show that Pit2 mimics PLCP substrates, and is cleaved to release a peptide tha
Externí odkaz:
https://doaj.org/article/495eae392b784d318ad6d240dd7dad05
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Scientific Reports
Scientific Reports
Caveolins are essential structural proteins driving the formation of caveolae, specialized invaginations of the plasma membrane. Loss of Caveolin-1 (Cav1) function in mice causes distinct neurological phenotypes leading to impaired motor control, how
A fungal substrate mimicking molecule suppresses plant immunity via an inter-kingdom conserved motif
Autor:
André N. Mueller, Ute Meyer, Jan Schulze Hüynck, Marlen Breuer, Johana C. Misas Villamil, Joe Win, Pitter F. Huesgen, Gunther Doehlemann, Bilal Ökmen, Helen Dauben, Fatih Demir
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Nature Communications
Nature Communications 10(1), 1576 (2019). doi:10.1038/s41467-019-09472-8
Nature Communications
Nature Communications 10(1), 1576 (2019). doi:10.1038/s41467-019-09472-8
Ustilago maydis is a biotrophic fungus causing corn smut disease in maize. The secreted effector protein Pit2 is an inhibitor of papain-like cysteine proteases (PLCPs) essential for virulence. Pit2 inhibitory function relies on a conserved 14 amino a
Autor:
Martina Podleschny, Ralf Jacob, Hanna Peradziryi, Hanna Berger, Annette Borchers, Marlen Breuer
Publikováno v:
Journal of cell science. 130(11)
Protein tyrosine kinase 7 (PTK7) is an evolutionarily conserved transmembrane receptor with important roles in embryonic development and disease. Originally identified as a gene upregulated in colon cancer, it was later shown to regulate planar cell
Publikováno v:
Scientific Reports. 10/5/2020, Vol. 10 Issue 1, pN.PAG-N.PAG. 1p.
Publikováno v:
American Journal of Medical Genetics. Part C: Seminars in Medical Genetics; Dec2017, Vol. 175 Issue 4, p478-486, 9p
Autor:
Misas Villamil, Johana C., Mueller, André N., Demir, Fatih, Meyer, Ute, Ökmen, Bilal, Schulze Hüynck, Jan, Breuer, Marlen, Dauben, Helen, Win, Joe, Huesgen, Pitter F., Doehlemann, Gunther
Publikováno v:
Nature Communications; 4/5/2019, Vol. 10 Issue 1, pN.PAG-N.PAG, 1p