Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Marleen Van Troys"'
Autor:
Jianjiang Hu, Xavier Serra‐Picamal, Gert‐Jan Bakker, Marleen Van Troys, Sabina Winograd‐Katz, Nil Ege, Xiaowei Gong, Yuliia Didan, Inna Grosheva, Omer Polansky, Karima Bakkali, Evelien Van Hamme, Merijn van Erp, Manon Vullings, Felix Weiss, Jarama Clucas, Anna M Dowbaj, Erik Sahai, Christophe Ampe, Benjamin Geiger, Peter Friedl, Matteo Bottai, Staffan Strömblad
Publikováno v:
Molecular Systems Biology, Vol 19, Iss 6, Pp 1-15 (2023)
Abstract High‐content image‐based cell phenotyping provides fundamental insights into a broad variety of life science disciplines. Striving for accurate conclusions and meaningful impact demands high reproducibility standards, with particular rel
Externí odkaz:
https://doaj.org/article/732ee8bfa8294913a63eccb0f9aa6998
Autor:
Irene Kleinberger, Ellen Sanders, Katrien Staes, Marleen Van Troys, Shinji Hirano, Tino Hochepied, Kelly Lemeire, Liesbet Martens, Christophe Ampe, Frans van Roy
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-33 (2022)
Abstract Background Nonclustered mouse protocadherin genes (Pcdh) encode proteins with a typical single ectodomain and a cytoplasmic domain with conserved motifs completely different from those of classic cadherins. Alternative splice isoforms differ
Externí odkaz:
https://doaj.org/article/f67b0e732ff24d6cb6c18854c8488483
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 9, p 3093 (2020)
Mutations in actins have been linked to several developmental diseases. Their occurrence across different cancers has, however, not been investigated. Using the cBioPortal database we show that human actins are infrequently mutated in patient samples
Externí odkaz:
https://doaj.org/article/5b00fb8bb3f24a3e92c3890a9e823057
Autor:
Jianjiang Hu, Xavier Serra-Picamal, Gert-Jan Bakker, Marleen Van Troys, Sabina Winograd-katz, Nil Ege, Xiaowei Gong, Yuliia Didan, Inna Grosheva, Omer Polansky, Karima Bakkali, Evelien Van Hamme, Merijn Van Erp, Manon Vullings, Felix Weiss, Jarama Clucas, Anna M. Dowbaj, Erik Sahai, Christophe Ampe, Benjamin Geiger, Peter Friedl, Matteo Bottai, Staffan Strömblad
High-content image-based cell phenotyping provides fundamental insights in a broad variety of life science areas. Striving for accurate conclusions and meaningful impact demands high reproducibility standards, even more importantly with the advent of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13a169c6417efed2c58105be7f2b1482
https://doi.org/10.1101/2022.11.18.516878
https://doi.org/10.1101/2022.11.18.516878
Autor:
Stefano Sala, Marie Catillon, Ermin Hadzic, Elisabeth Schaffner-Reckinger, Marleen Van Troys, Christophe Ampe
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0177879 (2017)
The focal adhesion protein testin is a modular scaffold and tumour suppressor that consists of an N-terminal cysteine rich (CR) domain, a PET domain of unknown function and three C-terminal LIM domains. Testin has been proposed to have an open and a
Externí odkaz:
https://doaj.org/article/3965ee295970438499a204ec6d189f52
Autor:
Laia Miret-Casals, Willem Vannecke, Kurt Hoogewijs, Gianluca Arauz-Garofalo, Marina Gay, Mireia Díaz-Lobo, Marta Vilaseca, Christophe Ampe, Marleen Van Troys, Annemieke Madder
Publikováno v:
Chemical Communications. 57:6054-6057
We describe furan as a triggerable 'warhead' for site-specific cross-linking using the actin and thymosin β4 (Tβ4)-complex as model of a weak and dynamic protein-protein interaction (PPI) with known 3D structure and with application potential in di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78343ad618cc810ec9979f45ba1b5d7f
https://doi.org/10.1039/d1cc01731d
https://doi.org/10.1039/d1cc01731d
Autor:
Ermin Hadzic, Marie Catillon, Aliaksandr Halavatyi, Sandrine Medves, Marleen Van Troys, Michèle Moes, Michelle A Baird, Michael W Davidson, Elisabeth Schaffner-Reckinger, Christophe Ampe, Evelyne Friederich
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140511 (2015)
Focal adhesions are integrin-based structures that link the actin cytoskeleton and the extracellular matrix. They play an important role in various cellular functions such as cell signaling, cell motility and cell shape. To ensure and fine tune these
Externí odkaz:
https://doaj.org/article/b59aa682bbb84994a0288087983bc78a
Autor:
Krzysztof Kolmus, Marleen Van Troys, Karlien Van Wesemael, Christophe Ampe, Guy Haegeman, Jan Tavernier, Sarah Gerlo
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e90649 (2014)
The proinflammatory cytokine Tumour Necrosis Factor (TNF)-α is implicated in a variety of skeletal muscle pathologies. Here, we have investigated how in vitro cotreatment of skeletal muscle C2C12 cells with β-agonists modulates the TNF-α-induced i
Externí odkaz:
https://doaj.org/article/06c041c049a948dab8189874d137a6b9
Autor:
Mischa Moeller, Matthias Gunzer, Lea Bornemann, Karl-Heinz Jöckel, Lennart Martens, Noreen Pundt, Laura Witjes, Benedikt W. Pelzer, Katja Kruithoff, Christina Kohn, Arnd Nusch, Clara Bessen, Olga Just, Ulrich Germing, Rainer Haas, Saskia Schmitz, Christophe Ampe, Marleen Van Troys, Marc Schuster, Charlyn Sobczak, Andrea Kündgen
Publikováno v:
The Journal of Immunology. 201:3546-3557
Autonomous migration is a central characteristic of immune cells, and changes in this function have been correlated to the progression and severity of diseases. Hence, the identification of pathologically altered leukocyte migration patterns might be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d95106d497fbf43f7d743194c39cd407
https://doi.org/10.4049/jimmunol.1801071
https://doi.org/10.4049/jimmunol.1801071
Publikováno v:
Actin Cytoskeleton in Cancer Progression and Metastasis – Part C ISBN: 9780128241387
Actins form a strongly conserved family of proteins that are central to the functioning of the actin cytoskeleton partaking in natural processes such as cell division, adhesion, contraction and migration. These processes, however, also occur during t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4f774e2732a8669383c3296335802e3
https://doi.org/10.1016/bs.ircmb.2021.02.017
https://doi.org/10.1016/bs.ircmb.2021.02.017