Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Marleen Renders"'
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Insertions and deletions (indels) are known to affect function, biophysical properties and substrate specificity of enzymes, and they play a central role in evolution. Despite such clear significance, this class of mutation remains an undere
Externí odkaz:
https://doaj.org/article/c189ef69ca0b404eb475c4a61034aca1
Publikováno v:
Belgeo, Vol 4, Pp 297-314 (2001)
In a large number of countries, fundamental shifts are taking place in the balance of power between political parties or movements. In nearly all cases, the nature of political discourse underlying national politics has changed radically, the politic
Externí odkaz:
https://doaj.org/article/fcf2c3b339c741aaaf73c51a718e8ca1
Autor:
Marleen Renders
Can ‘traditional'leaders and institutions help to build more legitimate, accountable and effective governments in polities or ‘states'under (re)construction? This book investigates the case of “Somaliland”, the 20-year old non-recognized stat
Publikováno v:
Chembiochem
Directed evolution has been remarkably successful at expanding the chemical and functional boundaries of biology. That progress is heavily dependent on the robustness and flexibility of the available selection platforms, given the significant cost to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd079b684b1209b5e8d355cb08f71b00
https://pubmed.ncbi.nlm.nih.gov/32413179
https://pubmed.ncbi.nlm.nih.gov/32413179
Although directed evolution has been remarkably successful at expanding the chemical and functional boundaries of biology, it is limited by the robustness and flexibility of available selection platforms – traditionally designed around a single des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30ee964ac35feda74cc298e0218d6ee7
Autor:
Guy Schepers, Piet Herdewijn, Vitor B. Pinheiro, Mikhail Abramov, Marleen Renders, Jef Rozenski, Donaat Kestemont, Piotr Leonczak
Publikováno v:
Chemical Communications
Chemical Communications, 2018, 54 (49), pp.6408-6411. ⟨10.1039/c8cc02414f⟩
Chemical Communications, Royal Society of Chemistry, 2018, 54 (49), pp.6408-6411. ⟨10.1039/c8cc02414f⟩
Chemical Communications, 2018, 54 (49), pp.6408-6411. ⟨10.1039/c8cc02414f⟩
Chemical Communications, Royal Society of Chemistry, 2018, 54 (49), pp.6408-6411. ⟨10.1039/c8cc02414f⟩
T4 DNA ligase is capable of ligating 2'OMe-RNA duplexes, HNA, LNA and FANA mixed sequences in the presence of 10% w/v PEG8000 and 3 M betaine. The enzymatic joining of oligonucleotides containing multiple consecutive XNA nucleotides at the ligation s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20a087d9bbace9a78cebbcff683135f9
https://doi.org/10.1039/c8cc02414f
https://doi.org/10.1039/c8cc02414f
Autor:
Shrinivas G. Dumbre, Dominique Toye, Piet Herdewijn, Christopher Cozens, Vitor B. Pinheiro, Julie Vandenameele, Jean-Marie Frère, Marleen Renders, Mikhail Abramov, Donaat Kestemont, Eric Largy, Lia Margamuljana
Publikováno v:
Nucleic Acids Research
Six 1',5'-anhydrohexitol uridine triphosphates were synthesized with aromatic substitutions appended via a carboxamide linker to the 5-position of their bases. An improved method for obtaining such 5-substituted hexitol nucleosides and nucleotides is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::296d7ad43703f1852fb7d1d3cd11cb1c
https://pubmed.ncbi.nlm.nih.gov/30698800
https://pubmed.ncbi.nlm.nih.gov/30698800
Publikováno v:
CHEMICAL REVIEWS
This review focuses on 4'-hydroxymethyl- or nucleobase-transposed nucleosides, nucleotides, and nucleoside phosphonates, their stereoisomers, and their close analogues. The biological activities of all known 4'-hydroxymethyl- or nucleobase-transposed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1e8e1147436c635212683944cd71815
https://doi.org/10.1021/acs.chemrev.5b00545
https://doi.org/10.1021/acs.chemrev.5b00545
Insertions and deletions (indels) are known to affect function, biophysical properties and substrate specificity of enzymes, and they play a central role in evolution. Despite such clear significance, this class of mutation remains an underexploited
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cde5913bcda91c8b8f96b0c26c1c3ecc
Publikováno v:
Current Protocols in Chemical Biology. 11:e62
T4 DNA ligase in high concentrations of certain crowding agents and cosolutes catalyzes the synthesis of a series of backbone-modified oligonucleotides that are difficult to obtain chemically. Backbone-modified nucleic acids are often enzymatically a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aedba11e497abc51d9600f384cc53a3b
https://doi.org/10.1002/cpch.62
https://doi.org/10.1002/cpch.62