Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Marleen H. M. E. van Stevendaal"'
Autor:
Wiggert J. Altenburg, N. Amy Yewdall, Daan F. M. Vervoort, Marleen H. M. E. van Stevendaal, Alexander F. Mason, Jan C. M. van Hest
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Mimicking the crowded cytosol of cells in synthetic cells has been a major limitation to the functionality. Here, the authors used the interaction between nickel, nitrilotriacetic acid and histidine tagged proteins to control loading of macromolecule
Externí odkaz:
https://doaj.org/article/2f279e085191415dabac0fab918c9cf7
Autor:
Floris J. van Dalen, Marleen H. M. E. van Stevendaal, Felix L. Fennemann, Martijn Verdoes, Olga Ilina
Publikováno v:
Molecules, Vol 24, Iss 1, p 9 (2018)
The tumour microenvironment (TME) is composed of extracellular matrix and non-mutated cells supporting tumour growth and development. Tumour-associated macrophages (TAMs) are among the most abundant immune cells in the TME and are responsible for the
Externí odkaz:
https://doaj.org/article/bbde0751d9804250a5e2ed630f69acad
Autor:
Bingbing Sun, Xiaoping Guo, Mei Feng, Shoupeng Cao, Haowen Yang, Hanglong Wu, Marleen H. M. E. van Stevendaal, Roy A. J. F. Oerlemans, Jinning Liang, Yiqiang Ouyang, Jan C. M. van Hest
Publikováno v:
Angewandte Chemie-International Edition, 61(38):e202208732. Wiley
Angewandte Chemie, 134(38):e202208732. Wiley-VCH Verlag
Angewandte Chemie, 134(38):e202208732. Wiley-VCH Verlag
Photodynamic therapy (PDT) is a highly promising therapeutic modality for cancer treatment. The development of stimuli-responsive photosensitizer nanomaterials overcomes certain limitations in clinical PDT. Herein, we report the rational design of a
Autor:
Marleen H. M. E. van Stevendaal, Jan C. M. van Hest, Robin Heiringhoff, Suzanne B. P. E. Timmermans, Daan F. M. Vervoort
Publikováno v:
Bioconjugate Chemistry, 32(5), 958-963. American Chemical Society
Bioconjugate Chemistry
Bioconjugate Chemistry
Protein cages hold much promise as carrier systems in nanomedicine, due to their well-defined size, cargo-loading capacity, and inherent biodegradability. In order to make them suitable for drug delivery, they have to be stable under physiological co
Autor:
Tsuyoshi Mashima, Marleen H. M. E. van Stevendaal, Femke R. A. Cornelissens, Alexander F. Mason, Bas J. H. M. Rosier, Wiggert J. Altenburg, Koji Oohora, Shota Hirayama, Takashi Hayashi, Jan C. M. van Hest, Luc Brunsveld
Publikováno v:
Angewandte Chemie-International Edition, 61(17):e202115041. Wiley
The regulation of protein uptake and secretion is crucial for (inter)cellular signaling. Mimicking these molecular events is essential when engineering synthetic cellular systems. A first step towards achieving this goal is obtaining control over the
Publikováno v:
ChemSystemsChem, 3(5):e2100009. Wiley-VCH Verlag
Bottom-up synthetic cells, where diverse non-living materials are combined in creative ways in order to construct increasingly life-like and adaptive systems, are fast approaching a level of function that will enable significant advances in solving s
Autor:
Marleen H. M. E. van Stevendaal, Pascal L.W. Welzen, David S. Williams, Loai K. E. A. Abdelmohsen, N. Amy Yewdall, Alexander F. Mason, Jan C. M. van Hest, Jingxin Shao
Publikováno v:
ACS Central Science, Vol 5, Iss 8, Pp 1360-1365 (2019)
ACS Central Science, 5(8), 1360-1365. American Chemical Society
ACS Central Science
ACS Central Science, 5(8), 1360-1365. American Chemical Society
ACS Central Science
A systemic feature of eukaryotic cells is the spatial organization of functional components through compartmentalization. Developing protocells with compartmentalized synthetic organelles is, therefore, a critical milestone toward emulating one of th
Autor:
Peter H.G.M. Willems, Jan A.M. Smeitink, Lisanne M.P.E. van Oppen, Werner J.H. Koopman, Roland Brock, Jan Pille, Christiaan Stuut, Jan C. M. van Hest, Marleen H. M. E. van Stevendaal, Lisa N. van der Vorm
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics, 137, 175-184. Elsevier
European Journal of Pharmaceutics and Biopharmaceutics, 137, 175-184
European Journal of Pharmaceutics and Biopharmaceutics, 137, pp. 175-184
European Journal of Pharmaceutics and Biopharmaceutics, 137, 175-184
European Journal of Pharmaceutics and Biopharmaceutics, 137, pp. 175-184
Contains fulltext : 202255.pdf (Publisher’s version ) (Closed access) Elastin-like polypeptide (ELP) nanoparticles are a versatile platform for targeted drug delivery. As for any type of nanocarrier system, an important challenge remains the abilit
Autor:
Jan C. M. van Hest, Laurynas Vasiukas, Alexander F. Mason, N. Amy Yewdall, Marleen H. M. E. van Stevendaal
Publikováno v:
ACS Applied Materials & Interfaces
Acs Applied Materials & Interfaces., 13, 7, pp. 7879-7889
Acs Applied Materials & Interfaces., 13, 7879-7889
ACS Applied Materials and Interfaces, 13(7), 7879-7889. American Chemical Society
Acs Applied Materials & Interfaces., 13, 7, pp. 7879-7889
Acs Applied Materials & Interfaces., 13, 7879-7889
ACS Applied Materials and Interfaces, 13(7), 7879-7889. American Chemical Society
Polymer-stabilized complex coacervate microdroplets have emerged as a robust platform for synthetic cell research. Their unique core-shell properties enable the sequestration of high concentrations of biologically relevant macromolecules and their su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::694704d14bd52ca89dd5598e66c54ae6
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/232247
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/232247
Autor:
Marleen H. M. E. van Stevendaal, Daan F. M. Vervoort, Jan C. M. van Hest, Alexander F. Mason, Wiggert J. Altenburg, N. Amy Yewdall
Publikováno v:
Nature Communications
Nature Communications, 11(1):6282. Nature Publishing Group
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Nature Communications, 11(1):6282. Nature Publishing Group
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
The cell cytosol is crowded with high concentrations of many different biomacromolecules, which is difficult to mimic in bottom-up synthetic cell research and limits the functionality of existing protocellular platforms. There is thus a clear need fo