Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Marla Tipping"'
Autor:
Nicole A. d’Almeida, Marla Tipping
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
Advancements in understanding the pathogenesis of C9orf72-associated frontotemporal dementia (C9orf72-FTD) have highlighted the role of repeat-associated non-ATG (RAN) translation and dipeptide repeat proteins (DPRs), with Drosophila melanogaster mod
Externí odkaz:
https://doaj.org/article/cc8b52c46ed4478b94645ee8f45d0e3a
Autor:
Simranjot Bawa, David S Brooks, Kathryn E Neville, Marla Tipping, Md Abdul Sagar, Joseph A Kollhoff, Geetanjali Chawla, Brian V Geisbrecht, Jason M Tennessen, Kevin W Eliceiri, Erika R Geisbrecht
Publikováno v:
eLife, Vol 9 (2020)
Cell growth and/or proliferation may require the reprogramming of metabolic pathways, whereby a switch from oxidative to glycolytic metabolism diverts glycolytic intermediates towards anabolic pathways. Herein, we identify a novel role for TRIM32 in
Externí odkaz:
https://doaj.org/article/b8f7ff5e057c440da2bb12f20db8fda5
Autor:
Jason M. Tennessen, David S. Brooks, Joseph A Kollhoff, Kathryn E. Neville, Geetanjali Chawla, Marla Tipping, Brian V. Geisbrecht, Kevin W. Eliceiri, Abdul Kader Sagar, Simranjot Bawa, Erika R. Geisbrecht
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
Cell growth and/or proliferation may require the reprogramming of metabolic pathways, whereby a switch from oxidative to glycolytic metabolism diverts glycolytic intermediates towards anabolic pathways. Herein, we identify a novel role for TRIM32 in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71163e4d476bd82f4924c1d24d959088
https://doi.org/10.7554/elife.52358
https://doi.org/10.7554/elife.52358
Autor:
Brian V. Geisbrecht, David S. Brooks, Kevin W. Eliceiri, Kathryn E. Neville, Abdul Kader Sagar, Marla Tipping, Simranjot Bawa, Erika R. Geisbrecht, Geetanjali Chawla, Joseph A Kollhoff, Jason M. Tennessen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a883009ee59d9373723be74618edfd1c
https://doi.org/10.7554/elife.52358.sa2
https://doi.org/10.7554/elife.52358.sa2
Publikováno v:
Journal of visualized experiments : JoVE. (138)
This protocol describes a method for measuring the metabolism in Drosophila melanogaster larval and adult brains. Quantifying metabolism in whole organs provides a tissue-level understanding of energy utilization that cannot be captured when analyzin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bfc4807376ff8574d5d17a6e5a1b81b3
https://pubmed.ncbi.nlm.nih.gov/30148485
https://pubmed.ncbi.nlm.nih.gov/30148485
Autor:
Marla Tipping, Carole L.C. Poon, Lucas G. Dent, Kieran F. Harvey, Xiaomeng Zhang, Joffrey L. Degoutin, Alexey Veraksa
Publikováno v:
Current Biology. 25:124-130
Summary The Salvador-Warts-Hippo (Hippo) pathway is a conserved regulator of organ size and is deregulated in human cancers [1]. In epithelial tissues, the Hippo pathway is regulated by fundamental cell biological properties, such as polarity and adh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea04accebc8db455ef5f894772bd83e6
https://doi.org/10.1016/j.cub.2014.11.041
https://doi.org/10.1016/j.cub.2014.11.041
Autor:
John F. Mills, James S. Waters, Mia Klekos, Marla Tipping, Steven E. Weicksel, Timothy L. Bosse, Kathryn E. Neville
Background Many neuronal and glial diseases have been associated with changes in metabolism. Therefore, metabolic reprogramming has become an important area of research to better understand disease at the cellular level, as well as to identify target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5430a64dfa286af6a7e218d62ef3dc16
https://europepmc.org/articles/PMC5840572/
https://europepmc.org/articles/PMC5840572/
Publikováno v:
Cancer Research. 79:4368-4368
Isocitrate dehydrogenase (IDH) has gained much attention due its frequent mutation in acute myeloid leukemia (AML) and glioblastomas. This enzyme is responsible for converting isocitrate into α-ketoglutarate (α-KG); when this gene is mutated it fur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6df3ea21fd4bf322f720cbaf5e27cac8
https://doi.org/10.1158/1538-7445.am2019-4368
https://doi.org/10.1158/1538-7445.am2019-4368
Publikováno v:
Developmental Cell. 20(5):700-712
SummaryMammalian cancers depend on “multiple hits,” some of which promote growth and some of which block apoptosis. We screened for mutations that require a synergistic block in apoptosis to promote tissue overgrowth and identified myopic (mop),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0fe09cd13286505210b8e05ce60735c
Autor:
Alexey Veraksa, Yoosik Kim, Stanislav Y. Shvartsman, Phillip Kyriakakis, Marla Tipping, Mei Tong
Publikováno v:
The EMBO Journal. 29:3222-3235
β-Arrestins have been implicated in the regulation of multiple signalling pathways. However, their role in organism development is not well understood. In this study, we report a new in vivo function of the Drosophila β-arrestin Kurtz (Krz) in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cb9e313279dcc231376715ca09fc4bd
https://doi.org/10.1038/emboj.2010.202
https://doi.org/10.1038/emboj.2010.202