Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Marla Tipping"'
Autor:
Nicole A. d’Almeida, Marla Tipping
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
Advancements in understanding the pathogenesis of C9orf72-associated frontotemporal dementia (C9orf72-FTD) have highlighted the role of repeat-associated non-ATG (RAN) translation and dipeptide repeat proteins (DPRs), with Drosophila melanogaster mod
Externí odkaz:
https://doaj.org/article/cc8b52c46ed4478b94645ee8f45d0e3a
Autor:
Simranjot Bawa, David S Brooks, Kathryn E Neville, Marla Tipping, Md Abdul Sagar, Joseph A Kollhoff, Geetanjali Chawla, Brian V Geisbrecht, Jason M Tennessen, Kevin W Eliceiri, Erika R Geisbrecht
Publikováno v:
eLife, Vol 9 (2020)
Cell growth and/or proliferation may require the reprogramming of metabolic pathways, whereby a switch from oxidative to glycolytic metabolism diverts glycolytic intermediates towards anabolic pathways. Herein, we identify a novel role for TRIM32 in
Externí odkaz:
https://doaj.org/article/b8f7ff5e057c440da2bb12f20db8fda5
Autor:
Jason M. Tennessen, David S. Brooks, Joseph A Kollhoff, Kathryn E. Neville, Geetanjali Chawla, Marla Tipping, Brian V. Geisbrecht, Kevin W. Eliceiri, Abdul Kader Sagar, Simranjot Bawa, Erika R. Geisbrecht
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
Cell growth and/or proliferation may require the reprogramming of metabolic pathways, whereby a switch from oxidative to glycolytic metabolism diverts glycolytic intermediates towards anabolic pathways. Herein, we identify a novel role for TRIM32 in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71163e4d476bd82f4924c1d24d959088
https://doi.org/10.7554/elife.52358
https://doi.org/10.7554/elife.52358
Autor:
Brian V. Geisbrecht, David S. Brooks, Kevin W. Eliceiri, Kathryn E. Neville, Abdul Kader Sagar, Marla Tipping, Simranjot Bawa, Erika R. Geisbrecht, Geetanjali Chawla, Joseph A Kollhoff, Jason M. Tennessen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a883009ee59d9373723be74618edfd1c
https://doi.org/10.7554/elife.52358.sa2
https://doi.org/10.7554/elife.52358.sa2
Publikováno v:
Cancer Research. 79:4368-4368
Isocitrate dehydrogenase (IDH) has gained much attention due its frequent mutation in acute myeloid leukemia (AML) and glioblastomas. This enzyme is responsible for converting isocitrate into α-ketoglutarate (α-KG); when this gene is mutated it fur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6df3ea21fd4bf322f720cbaf5e27cac8
https://doi.org/10.1158/1538-7445.am2019-4368
https://doi.org/10.1158/1538-7445.am2019-4368
Publikováno v:
Journal of visualized experiments : JoVE. (138)
This protocol describes a method for measuring the metabolism in Drosophila melanogaster larval and adult brains. Quantifying metabolism in whole organs provides a tissue-level understanding of energy utilization that cannot be captured when analyzin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bfc4807376ff8574d5d17a6e5a1b81b3
https://pubmed.ncbi.nlm.nih.gov/30148485
https://pubmed.ncbi.nlm.nih.gov/30148485
Autor:
Marla Tipping, Carole L.C. Poon, Lucas G. Dent, Kieran F. Harvey, Xiaomeng Zhang, Joffrey L. Degoutin, Alexey Veraksa
Publikováno v:
Current Biology. 25:124-130
Summary The Salvador-Warts-Hippo (Hippo) pathway is a conserved regulator of organ size and is deregulated in human cancers [1]. In epithelial tissues, the Hippo pathway is regulated by fundamental cell biological properties, such as polarity and adh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea04accebc8db455ef5f894772bd83e6
https://doi.org/10.1016/j.cub.2014.11.041
https://doi.org/10.1016/j.cub.2014.11.041
Autor:
John F. Mills, James S. Waters, Mia Klekos, Marla Tipping, Steven E. Weicksel, Timothy L. Bosse, Kathryn E. Neville
Background Many neuronal and glial diseases have been associated with changes in metabolism. Therefore, metabolic reprogramming has become an important area of research to better understand disease at the cellular level, as well as to identify target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5430a64dfa286af6a7e218d62ef3dc16
https://europepmc.org/articles/PMC5840572/
https://europepmc.org/articles/PMC5840572/
Publikováno v:
Molecular Cancer Therapeutics. 17:B018-B018
Metabolic reprogramming has been detected in many diseases, including cancer. Recently, a small number of metabolic enzymes have been identified as driver mutations for various types of cancer. To better understand how these genes lead to cancer, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e9e86cd9be2c336c8c6c6aa5fc74af5
https://doi.org/10.1158/1535-7163.targ-17-b018
https://doi.org/10.1158/1535-7163.targ-17-b018
Autor:
Kathryn E. Neville, Richard Tartarini, Nicholas DiDuca, Meghan O'Connor, Joseph Stallone, Mira Magner, Marla Tipping, Julia Fabiano, Gabriela Chiaramida
Publikováno v:
Cancer Research. 77:1827-1827
Metabolic reprogramming is a common hallmark shared by nearly all proliferating cancer cells, and thus has emerged as an exciting new direction in cancer research. Many signaling pathways have been implicated in mechanisms leading to the shift of met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::058608368a69571f650ed7e62f67d0f8
https://doi.org/10.1158/1538-7445.am2017-1827
https://doi.org/10.1158/1538-7445.am2017-1827