Zobrazeno 1 - 10
of 640
pro vyhledávání: '"Marla Dubinsky"'
Autor:
Vipul Jairath, Theresa Hunter Gibble, Richard Moses, Brittany Klooster, Leighann Litcher-Kelly, Marisa Walker, Madison C Bernstein, Kaelyn Rupinski, Megan McLafferty, Simon Travis, Marla Dubinsky
Publikováno v:
Journal of Patient-Reported Outcomes, Vol 8, Iss 1, Pp 1-13 (2024)
Abstract Objectives Bowel urgency is an impactful core symptom of ulcerative colitis (UC). Patient-reported outcome (PRO) questionnaires have been developed and used to assess the patient experience of this important symptom. The objective of this pa
Externí odkaz:
https://doaj.org/article/9d9149c1905549d09deb54d9ec716dc0
Autor:
Pablo Canales-Herrerias, Yolanda Garcia-Carmona, Joan Shang, Hadar Meringer, Debra S. Yee, Lin Radigan, Sofija Buta, Gustavo Martinez-Delgado, Michael Tankelevich, Drew Helmus, Marla Dubinsky, Annelie Everts-van der Mind, Thierry Dervieux, Dusan Bogunovic, Jean-Frederic Colombel, Jason M. Brenchley, Jeremiah Faith, Charlotte Cunningham-Rundles, Andrea Cerutti, Saurabh Mehandru
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 12 (2023)
Externí odkaz:
https://doaj.org/article/6c4e096e26384d1ab3d1fba19786baa0
Autor:
Roman Kosoy, Seunghee Kim-Schulze, Adeeb Rahman, Joshua R. Friedman, Ruiqi Huang, Lauren A. Peters, El-ad Amir, Jacqueline Perrigoue, Aleksandar Stojmirovic, Won-min Song, Hao Ke, Ryan Ungaro, Saurabh Mehandru, Judy Cho, Marla Dubinsky, Mark Curran, Carrie Brodmerkel, Eric E. Schadt, Bruce E. Sands, Jean-Frederic Colombel, Andrew Kasarskis, Carmen A. Argmann, Mayte Suárez-Fariñas
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 2, Pp 599-632 (2021)
Background: Inflammatory bowel disease (IBD) is a complex disease with variable presentation, progression, and response to therapies. Current disease classification is based on subjective clinical phenotypes. The peripheral blood immunophenome can re
Externí odkaz:
https://doaj.org/article/ce39650906404858884de64148570f38
Autor:
Vipul Jairath, Guangyong Zou, Niels Vande Casteele, Michelle Smith, Marla Dubinsky, Konstantinos Papamichael, Bruce Sands, John Valentine, Corey Siegel, Benjamin Cohen, Timothy Ritter, Adam Cheifetz
Publikováno v:
BMJ Open, Vol 12, Iss 4 (2022)
Introduction Preliminary data indicates that proactive therapeutic drug monitoring (TDM) is associated with better outcomes compared with empiric dose escalation and/or reactive TDM, and that pharmacokinetic (PK) modelling can improve the precision o
Externí odkaz:
https://doaj.org/article/161f703574cc44a98b68489ed44f9688
Autor:
Megan Clowse, Rebecca Fischer-Betz, Catherine Nelson-Piercy, Angela E. Scheuerle, Brigitte Stephan, Marla Dubinsky, Thomas Kumke, Rachna Kasliwal, Bernard Lauwerys, Frauke Förger
Publikováno v:
Therapeutic Advances in Musculoskeletal Disease, Vol 14 (2022)
Introduction: Chronic inflammatory diseases (CIDs), including rheumatic diseases and other inflammatory conditions, often affect women of reproductive age. Tumor necrosis factor inhibitors (TNFi) are widely used to treat CID, but there is limited inf
Externí odkaz:
https://doaj.org/article/e65b18e6d5e1489cb9a40567081e5652
Autor:
Xin Chen, Joanne Lai, Ying Song, Nan Yang, Sacha Gnjatic, Virginia Gillespie, William Hahn, Ezra Chefitz, Nanci Pittman, Jacqueline Jossen, Keith Benkov, Marla Dubinsky, Xiu-Min Li, David Dunkin
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Background: TNF-α has a major role in the pathogenesis of Crohn's disease (CD). In contrast, GM-CSF may be beneficial for its anti-inflammatory role in a subset of patients with CD with antibodies against GM-CSF as seen in prior trials of GM-CSF whi
Externí odkaz:
https://doaj.org/article/521a66f5222847e49080b9430e771b59
Publikováno v:
Qualitative Research in Medicine & Healthcare, Vol 4, Iss 2 (2020)
The Patient-Centered Medical Home model has gained popularity in primary care to provide early effective care to patients with chronic conditions. Prior research on specialty medical homes has been cross-sectional and focused on patient outcomes. The
Externí odkaz:
https://doaj.org/article/e5ff410aade24655838acbaac0753465
Autor:
Inga Peter, Ana Maldonado-Contreras, Caroline Eisele, Christine Frisard, Shauna Simpson, Nilendra Nair, Alexa Rendon, Kelly Hawkins, Caitlin Cawley, Anketse Debebe, Leonid Tarassishin, Sierra White, Marla Dubinsky, Joanne Stone, Jose C Clemente, Joao Sabino, Joana Torres, Jianzhong Hu, Jean-Frederic Columbel, Barbara Olendzki
Publikováno v:
Contemporary Clinical Trials Communications, Vol 18, Iss , Pp 100573- (2020)
Crohn's disease (CD), a type of inflammatory bowel disease (IBD), is a chronic condition of the gastrointestinal tract that is caused by the loss of mucosal tolerance towards the commensal bacteria resulting in inflammatory responses. It has long bee
Externí odkaz:
https://doaj.org/article/2a2b2ea8c9854e2195bf70b58b624dcd
Autor:
Jonathan P. Jacobs, Maryam Goudarzi, Namita Singh, Maomeng Tong, Ian H. McHardy, Paul Ruegger, Miro Asadourian, Bo-Hyun Moon, Allyson Ayson, James Borneman, Dermot P.B. McGovern, Albert J. Fornace, Jr., Jonathan Braun, Marla Dubinsky
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 2, Iss 6, Pp 750-766 (2016)
Background & Aims: Microbes may increase susceptibility to inflammatory bowel disease (IBD) by producing bioactive metabolites that affect immune activity and epithelial function. We undertook a family based study to identify microbial and metabolic
Externí odkaz:
https://doaj.org/article/5b85786fde5b4825a158fb3d16ff066c
Autor:
Eduardo J Contijoch, Graham J Britton, Chao Yang, Ilaria Mogno, Zhihua Li, Ruby Ng, Sean R Llewellyn, Sheela Hira, Crystal Johnson, Keren M Rabinowitz, Revital Barkan, Iris Dotan, Robert P Hirten, Shih-Chen Fu, Yuying Luo, Nancy Yang, Tramy Luong, Philippe R Labrias, Sergio Lira, Inga Peter, Ari Grinspan, Jose C Clemente, Roman Kosoy, Seunghee Kim-Schulze, Xiaochen Qin, Anabella Castillo, Amanda Hurley, Ashish Atreja, Jason Rogers, Farah Fasihuddin, Merjona Saliaj, Amy Nolan, Pamela Reyes-Mercedes, Carina Rodriguez, Sarah Aly, Kenneth Santa-Cruz, Lauren Peters, Mayte Suárez-Fariñas, Ruiqi Huang, Ke Hao, Jun Zhu, Bin Zhang, Bojan Losic, Haritz Irizar, Won-Min Song, Antonio Di Narzo, Wenhui Wang, Benjamin L Cohen, Christopher DiMaio, David Greenwald, Steven Itzkowitz, Aimee Lucas, James Marion, Elana Maser, Ryan Ungaro, Steven Naymagon, Joshua Novak, Brijen Shah, Thomas Ullman, Peter Rubin, James George, Peter Legnani, Shannon E Telesco, Joshua R Friedman, Carrie Brodmerkel, Scott Plevy, Judy H Cho, Jean-Frederic Colombel, Eric E Schadt, Carmen Argmann, Marla Dubinsky, Andrew Kasarskis, Bruce Sands, Jeremiah J Faith
Publikováno v:
eLife, Vol 8 (2019)
To identify factors that regulate gut microbiota density and the impact of varied microbiota density on health, we assayed this fundamental ecosystem property in fecal samples across mammals, human disease, and therapeutic interventions. Physiologic
Externí odkaz:
https://doaj.org/article/0030eccfbbf04caa9643ee26d5af44c0